Results 81 to 90 of about 20,640 (292)
Sex‐specific white matter alterations in children exposed to high pregestational BMI
Obesity, Volume 33, Issue 6, Page 1113-1125, June 2025.Abstract Objective This study investigated whether exposure to high pregestational BMI (≥ 25 kg/m2) is associated with alterations in white matter microstructure in early childhood, explored sex‐specific effects, and examined associations with cognitive performance. Methods A total of 90 children from the Alberta Pregnancy Outcomes and Nutrition (APrON)
Samson Nivins +5 more
wiley +1 more source
A combination of nifedipine and octreotide treatment in an hyperinsulinemic hypoglycemic infant. [PDF]
, 2016 PublishedResearch Support, Non-U.S. Gov'tThis is the final version of the article. Available from Galenos Publishing via the DOI in this record.Hyperinsulinemic hypoglycemia (HH) is the commonest cause of persistent hypoglycemia in the neonatal and ...
Akcurin, S +5 more
core +1 more source
AACE Clinical Case Reports, 2022 Background/Objective: AKT2 is a serine/threonine kinase that plays a key role in regulating insulin signaling. The phenotype related to the gain-of-function alteration in the AKT2 gene (c.49G>A, p.Glu17Lys) has been described in 5 patients with clinical ...
Maria Fernanda Ochoa Molina, MD +4 more
doaj
Physiological Reports, Volume 13, Issue 12, June 2025.Abstract Age‐ and disease‐related metabolic responses to prolonged passive heat exposure are poorly understood. We evaluated serum irisin and betatrophin responses to 9 h of passive heat exposure (40°C, 9% relative humidity) in 19 young adults (19–31 years) and 37 older adults (61–78 years), including those with hypertension (HTN) and type 2 diabetes ...
Joel M. Garrett +7 more
wiley +1 more source
Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion [PDF]
, 2001 A female infant of nonconsanguineous Indian parents presented at 4 months with a hypoglycemic convulsion. Further episodes of hypoketotic hypoglycemia were associated with inappropriately elevated plasma insulin concentrations.
Aynsley-Green, A +9 more
core
Glutamate induces autophagy via the two-pore channels in neural cells [PDF]
, 2016 NAADP (nicotinic acid adenine dinucleotide phosphate) has been proposed as a second messenger for glutamate in neuronal and glial cells via the activation of the lysosomal Ca2+ channels TPC1 and TPC2.
+11 more
core +3 more sources
Pediatric Annals, 2017 Congenital hyperinsulinism is a rare disorder that commonly presents in the immediate postnatal period as persistent hypoglycemia. The condition is frequently resistant to medical therapies, and the genetic mutations implicated in the disorder can be predictive of response to therapy.
Elena, Minakova, Alison, Chu
openaire +3 more sources
Biomedicines, 2023 Polycystic ovary syndrome (PCOS) is the most frequent endocrinopathy during women’s reproductive age. PCOS is a heterogeneous disorder featuring specific cardiometabolic properties.
Dejana Rakic +12 more
doaj +1 more source
Journal of Inherited Metabolic Disease, Volume 48, Issue 3, May 2025.ABSTRACT Continuous glucose monitoring (CGM) is increasingly used although not officially registered for the management of people living with liver glycogen storage diseases (GSDs). The aims of this study were twofold: (a) to investigate the current experiences of healthcare providers (HCPs), patients, and caregivers using CGM to monitor glucose ...
Terry G. J. Derks +116 more
wiley +1 more source
Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys. [PDF]
, 2014 Polycystic ovary syndrome (PCOS) is prevalent in reproductive-aged women and confounded by metabolic morbidities, including insulin resistance and type 2 diabetes.
Abbott, David H +5 more
core +3 more sources