Results 161 to 170 of about 116,541 (302)

Chemical Exposures, DNA Methylation and Whole Blood DNA Damage in Pet Golden Retrievers

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine multicentric lymphoma (CL) is a common and typically fatal cancer among dogs. Although certain breeds have a higher incidence of CL, its environmental risk factors remain uncertain. Exposures to herbicides and volatile organic compounds (VOCs) associate with non‐Hodgkin lymphoma in people.
Ashleigh N. Tindle, Mark E. Berres, Lauren Baker, Zhuonan Wu, Brenna Swafford, Julia Labadie, Lauren A. Trepanier   +6 more
wiley   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

<i>NOS1</i> hypermethylation may participate in the colorectal cancer development and be associated with its prognosis. [PDF]

Epigenetics
Zhang Z, Yeerken A, Shao X, Qian S, Lin S, Gu S, Ying X, Li Z, Fei X, Yang J, Tang M, Wang J, Jin M, Chen K.   +13 more
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Early blood DNA methylation patterns associated with glycemic progression in a prospective Indian cohort. [PDF]

Clin Epigenetics
Satheesh G, Asokan AK, Vijayakumar G, Rajavelu A, Rao SN, Sivakumar KC, Jaleel A.   +6 more
europepmc   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

Global Research Trends in Gastric Cancer Epigenetics From 2005 to 2025. [PDF]

Cureus
Yuan D, Li Y, Yi H, Lei Y, Zhou Y.
europepmc   +1 more source

Genome‐wide analysis of DNA methyltransferases in a model extremophyte, Schrenkiella parvula: Transcriptional dynamics during development and under salt stress

Annals of Applied Biology, Volume 189, Issue 1, July 2026.
Classification of DMTs into 4 subfamilies: two METs, three CMTs, three DRMs, and one DNMT2. The cis‐elements are associated with stress‐response, hormonal regulation, light‐response, and development. RNA‐seq analysis revealed differential expression of DMTs under NaCl stress.
Seher Yolcu, Amin Mirshamsi Kakhki, Ahmad Jalilian, Emre Sevindik, Ismail Turkan   +4 more
wiley   +1 more source

DNA Methylation in Gastric Cancer and Preneoplastic Lesions: Emerging Insights and Future Directions. [PDF]

Cancers (Basel)
Ceccon C, Maddalena G, Angerilli V, Nappo F, Gasparello J, Sabbadin M, Toffolatti L, Bergamo F, Fassan M, Lonardi S.   +9 more
europepmc   +1 more source