Results 181 to 190 of about 70,734 (243)

Epigenetics: the master switch of nasopharyngeal carcinoma invasion and metastasis. [PDF]

Front Immunol
Chen H, Wu Y, Zhang K, Chen Z, Xu H, Xie C, Lin C, Pan X.   +7 more
europepmc   +1 more source

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy, Usamah Sayed, Zarina Nasirova, Quvonch Tursunov, Omer Qutaiba B. Allela, Lara Asim Kzar, Rajashree Panigrahi, Neeraj Bainsal   +7 more
wiley   +1 more source

Functional roles and clinical potential of SOX1 in cancer as a biomarker and therapeutic target. [PDF]

Discov Oncol
Zhou X, Wang J, Yang F, Gao Y, Hou C.
europepmc   +1 more source

Venetoclax for elderly patients with acute myeloid leukaemia unfit for intensive chemotherapy: Prospects, resistance mechanisms and management strategies

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Resistance to venetoclax has become a critical bottleneck limiting its long‐term clinical benefits. A thorough understanding of the underlying resistance mechanisms and the development of novel strategies to overcome resistance are central to improving survival outcomes in elderly AML patients. Abstract To date, the treatment of acute myeloid leukaemia
Jinlin Zhang, Jile Liu, Mohan Zhao, Xiaoyu Zhang, Linlin Liu, Mengnan Li, Changze Cao, Rui Zhang, Mingfeng Zhao   +8 more
wiley   +1 more source

Epigenetics of Genes Displaying High and Preferential Expression in Myoblasts. [PDF]

Epigenomes
Ehrlich KC, Lacey M, Pradhan S, Ehrlich M.   +3 more
europepmc   +1 more source

Iron‐Sulfur Cluster Targeting: A Novel Perspective for Treating Alcohol‐Related Lipid Metabolic Diseases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Alcohol metabolism induces structural instability of iron‐sulfur clusters through ROS‐mediated oxidative damage and direct covalent modification of acetaldehyde. The iron‐sulfur cluster deficiency drives metabolic reprogramming by inactivating aconitase, accumulating succinate, and impairing tRNA thiolation, thereby promoting hepatic steatosis ...
Li Xu, Zhenyang Xu, Chenli Su, Yanqian Zhao, Linjing Qiang, Xiayong Jing, Yuxiang Sun   +6 more
wiley   +1 more source

Correction: SPAG6 hypermethylation silences a novel tumor suppressor and inhibits renal cell carcinoma progression via PI3K/AKT/mTOR pathway. [PDF]

PLoS One
Wu T, Ji X, Yun Y, Wang X, Gan Y, Fan Y, Zhang Q.   +6 more
europepmc   +1 more source

Metabolic Syndrome: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 9, September 2026.
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley   +1 more source

Homologous recombination pathway alterations in basal-like breast cancer. [PDF]

Front Oncol
Aho S, Guyot B, Maguer-Satta V.
europepmc   +1 more source

METTL14‐Mediated N6‐Methyladenosine Exacerbates Acute Lung Injury via USP30/NCOA4‐Dependent Ferroptosis

MedComm, Volume 7, Issue 9, September 2026.
METTL14‐mediated N6‐methyladenosine aggravates ischemia/reperfusion‐induced acute lung injury by enhancing YTHDF1‐dependent USP30 expression. USP30 stabilizes NCOA4 through deubiquitination, thereby promoting ferritinophagy, iron accumulation, lipid peroxidation, and ferroptosis in lung epithelial cells.
Aming Sang, Qiongyue Zhang, Xianwu Zhou, Xiaohua Wang, Jin Wang, Xuemin Song, Li Li, Ling Li, Xinyi Li   +8 more
wiley   +1 more source