Results 181 to 190 of about 116,541 (302)

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang, Qitai Chen, YuJie Yu, Yi Zang, Rujia Zheng, Zhe Zhang, Shuaijun Lu, Li Zhou   +7 more
wiley   +1 more source

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer. [PDF]

Oncol Lett
Nakamura M, Hagiwara T, Yamada K, Igari T, Fukumura Y, Saiura A, Takemura N, Kokudo N, Kawamura YI.   +8 more
europepmc   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source

The molecular mechanisms and potential therapeutic implications of the crosstalk between DNA methylation and metabolic reprogramming in thyroid cancer. [PDF]

Cell Death Discov
Zhang T, Han H, Zhang Y, Zhang T, Ma L, Yang Z, Zhao YX.   +6 more
europepmc   +1 more source

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Epigenetics of Genes Displaying High and Preferential Expression in Myoblasts. [PDF]

Epigenomes
Ehrlich KC, Lacey M, Pradhan S, Ehrlich M.   +3 more
europepmc   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan, Mukesh Rathore, Dinesh Kumar Saini, Ayushi Singh, Naeela Qureshi, Nikita Aggarwal, Mahpara Bashir, Mehnaz Shakeel, Vikas Gupta, Sundeep Kumar, Rajeev Kumar Varshney, Reyazul Rouf Mir   +11 more
wiley   +1 more source

Correction: SPAG6 hypermethylation silences a novel tumor suppressor and inhibits renal cell carcinoma progression via PI3K/AKT/mTOR pathway. [PDF]

PLoS One
Wu T, Ji X, Yun Y, Wang X, Gan Y, Fan Y, Zhang Q.   +6 more
europepmc   +1 more source

SOX1/PAX1 Methylation for Triage of HPV‐Positive Women in Cervical Cancer Screening: A Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 7, Page 1431-1440, June 2026.
ABSTRACT Objective To establish a better triage strategy using SOX1/PAX1 methylation detection for high‐risk HPV (hrHPV)‐positive women than cytology. Design A cohort study. Setting Population‐based cervical cancer (CC) screening cohort. Population A total of 5684 women were enrolled.
Hongyu Xie, Junyan Li, Huiru Huang, Ansong Emmanuel, Hui Wang, Weiguo Lu, Xiao Li   +6 more
wiley   +1 more source

A Case of IDH-Mutant Astrocytoma Harboring an IDH2 R172_H173delinsSN Variant. [PDF]

Neuropathology
Auen T, Chen J, Shonka N, Cathcart S.
europepmc   +1 more source