Results 171 to 180 of about 116,541 (302)

Epigenetics of Malignant Melanoma: Mechanisms, Diagnostic Approaches and Therapeutic Applications. [PDF]

Oncol Res
Hong SG, Murphy GF, Lian CG.
europepmc   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu, Yanjiao Huang, Chenyue Hu, Wenli Ding, Zhenwei Pu, Qiang Li, Zhiliang Xu   +6 more
wiley   +1 more source

The Role of DNA Methylation in Osteosarcoma Pathogenesis and Therapy. [PDF]

Onco Targets Ther
Zhou X, Li B, Tao P.
europepmc   +1 more source

Interpreting pathways to discover cancer driver genes with Moonlight [PDF]

, 2020
al., et, Bailey, Matthew H., Colaprico, Antonio   +2 more
core   +1 more source

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

Molecular mechanisms and therapeutic strategies: DNA methylation in pancreatic cancer. [PDF]

Cancer Biol Ther
Liu J, Xie J, Ding Y.
europepmc   +1 more source

DRAM1‐defined autophagy‐JAK‐STAT‐Tregs axis drives immunosuppression and predicts immunotherapy response in pan‐cancer

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Tumour‐intrinsic DRAM1, induced by DNA damage and IFN‐γ, activates an autophagy/JAK‐STAT axis that recruits Tregs, causing CD8+ T cell exhaustion and establishing a self‐sustaining, immunotherapy‐resistant “cold” tumour microenvironment. Abstract Background DNA damage‐regulated autophagy modulator 1 (DRAM1) is a lysosomal protein involved in autophagy ...
Jinchun Wu, Hailing Yang, Jingjing Cao, Min Yang, Wanqiao Cao, Yonglei Liu, Yunfeng Cheng, Fanli Hua   +7 more
wiley   +1 more source

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene. [PDF]

Oncol Rep
Wang X, Chen E, Yang X, Wang Y, Quan Z, Wu X, Luo C.   +6 more
europepmc   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Epigenetics: the master switch of nasopharyngeal carcinoma invasion and metastasis. [PDF]

Front Immunol
Chen H, Wu Y, Zhang K, Chen Z, Xu H, Xie C, Lin C, Pan X.   +7 more
europepmc   +1 more source