Results 41 to 50 of about 4,810 (156)

Inducing Oxalobacter formigenes Colonization Reduces Urinary Oxalate in Healthy Adults

Kidney International Reports
Introduction: Oxalate-degrading intestinal bacteria, including the oxalate-degrading specialist, Oxalobacter formigenes (O formigenes), have the potential to reduce urinary oxalate excretion in humans, and thus limit the risk of calcium oxalate kidney ...
Sonia Fargue, Mangesh Suryavanshi, Kyle D. Wood, Joseph J. Crivelli, Robert A. Oster, Dean G. Assimos, Aaron Miller, John Knight   +7 more
doaj   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, Volume 22, Issue 16, 17 March 2026.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Does instrumentation and irrigation configuration affect intrarenal pressure during PCNL?

BJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives To measure the effects of varying configurations of nephroscope sheath, irrigation, instruments, and suction on intrarenal pressure (IRP) during percutaneous nephrolithotomy (PCNL). Materials and Methods Kidney and ureter 3D printed models from a deidentified patient's CT scan were placed in a plaster and foam mould, simulating the ...
Evan Seibly, Ali Albaghli, Kyu Park, Elizabeth A. Baldwin, Ala'a Farkouh, Katya Hanessian, Nicole Mack, Cliff De Guzman, Toby Clark, Matthew Buell, Rose Leu, Kanha Shete, Sikai Song, Akin S. Amasyali, Zham Okhunov, D. Duane Baldwin   +15 more
wiley   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Sodium thiosulfate ameliorates oxidative stress and preserves renal function in hyperoxaluric rats. [PDF]

PLoS ONE, 2015
BACKGROUND: Hyperoxaluria causes crystal deposition in the kidney, which leads to oxidative stress and to injury and damage of the renal epithelium. Sodium thiosulfate (STS, Na2S2O3) is an anti-oxidant, which has been used in human medicine for decades ...
Rakesh K Bijarnia, Matthias Bachtler, Prakash G Chandak, Harry van Goor, Andreas Pasch   +4 more
doaj   +1 more source

Protective Effects of Quercetin on Oxidative Stress-Induced Tubular Epithelial Damage in the Experimental Rat Hyperoxaluria Model

Medicina, 2021
Background and Objectives: The most common kidney stones are calcium stones and calcium oxalate (CaOx) stones are the most common type of calcium stones. Hyperoxaluria is an essential risk factor for the formation of these stones.
Ahmet Guzel, Sedat Yunusoglu, Mustafa Calapoglu, Ibrahim Aydın Candan, Ibrahim Onaran, Meral Oncu, Osman Ergun, Taylan Oksay   +7 more
doaj   +1 more source

Computerized tomography‐derived body composition metrics are associated with 24‐h urine lithogenic parameters

BJUI Compass, Volume 7, Issue 1, January 2026.
Abstract Background The relationship between body composition and lithogenic urine parameters remains poorly defined. This study aimed to evaluate associations between computerized tomography (CT)‐derived body composition metrics and 24‐h urine findings. Methods Stone‐forming patients in our Nephrolithiasis Database who underwent 24‐h urine testing and
Reza Lahiji, Lorenzo Storino Ramacciotti, Ernie Morton, Edouard H. Nicaise, Adam Braunschweig, Gregory Palmateer, Benjamin Schmeusser, Dattatraya Patil, Maxwell Richardson, Frank Glover, Ethan Kearns, Aaron Lay, Mohammad Hajiha, Viraj A. Master, Kenneth Ogan   +14 more
wiley   +1 more source

Electroanalytical Overview: The Electroanalytical Detection of Oxalate

Sensors and Actuators Reports, 2023
The sensing of oxalate within urine has been recognised as one of the most important determinations in the investigation of patients with hyperoxaluria.
Robert D. Crapnell, Prashanth S. Adarakatti, Craig E. Banks   +2 more
doaj   +1 more source

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT A substantial proportion of fresh fruit undergoes processing, resulting in underutilized fruit by‑products (FBPs) that are rich in dietary fiber and bioactive compounds. Recent FBP valorization trends demonstrate that fermentation significantly enhances microbiological, nutritional, and sensory attributes, yielding value‑added food supplements.
Abouzar Ghasemi, Salwa Karboune, Denis Groleau, Ismail Fliss   +3 more
wiley   +1 more source

A case of failure to thrive secondary to primary hyperoxaluria type 1

Radiology Case Reports, 2020
Primary hyperoxaluria type 1 is a rare genetic condition characterized by oxalate deposition in the kidneys. We report findings of an 8-month old female presenting with failure to thrive, poor oral intake, and kidney stones resulting in the diagnosis of ...
Rachel Stern, MD, Vicky Kuo, MD, Sarah Rogal, MD, MPH, Carly Barron, MD, Raidour Ahmed, MD, Bernard Goldwasser, MD   +5 more
doaj   +1 more source