Results 111 to 120 of about 129,353 (325)

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

Advanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv, Yu Cao, Yuhan Wang, Yunhao Wu, Yingying Zhang, Kuanghao Ye, Xian Qiu, Qingfang Sun, Liuguan Bian, Halimureti Paerhati, Valerie Voon, Shikun Zhan, Bomin Sun   +12 more
wiley   +1 more source

Intermolecular Nuclear Spin Hyperpolarization Transfer via Cross‐Relaxation Triggers RASER of Solute Molecules

Angewandte Chemie, EarlyView.
Radiofrequency amplification by stimulated emission of radiation (RASER) of solutes was achieved via parahydrogen‐induced polarization (PHIP) and polarization transfer from the produced hyperpolarization donors to solutes via the intermolecular nuclear Overhauser effect (NOE).
Ivan A. Trofimov, Anna P. Yi, Oleg G. Salnikov, Andrey N. Pravdivtsev, Henri de Maissin, Eduard Y. Chekmenev, Jan‐Bernd Hövener, Andreas B. Schmidt, Igor V. Koptyug   +8 more
wiley   +2 more sources

Cardiac pH-Imaging With Hyperpolarized MRI

Frontiers in Cardiovascular Medicine, 2020
Regardless of the importance of acid-base disturbances in cardiac disease, there are currently no methods for clinical detection of pH in the heart. Several magnetic resonance imaging techniques hold translational promise and may enable in-vivo mapping ...
Nikolaj Bøgh, Esben Søvsø Szocska Hansen, Christian Østergaard Mariager, Lotte Bonde Bertelsen, Steffen Ringgaard, Christoffer Laustsen   +5 more
doaj   +1 more source

Decay of nuclear hyperpolarization in silicon microparticles [PDF]

, 2011
We investigate the low-field relaxation of nuclear hyperpolarization in undoped and highly doped silicon microparticles at room temperature following removal from high field.
A. Abragam, A. Abragam, C. M. Marcus, C. Ramanathan, M. C. Cassidy, M. Lee, N. T. Bagraev, N. T. Bagraev, N. T. Bagraev, N. T. Bagraev   +9 more
core   +3 more sources

Hyperpolarized MR – What’s up Doc? [PDF]

Journal of Magnetic Resonance, 2019
Hyperpolarized MR by dissolution Dynamic Nuclear Polarization (dDNP) appeared on the scene in 2003. Since then, it has been translated to the clinic and several sites are now conducting human studies. This has happened at record pace despite all its complexities. The method has reached a pivotal point, and the coming years will be critical in realizing
openaire   +3 more sources

Pierceable, Water‐Resistant, and Transparent Nanofilm Electrodes Comprising Carbon Nanotubes for Long‐Term Monitoring of Plant Electrophysiology

Advanced Science, EarlyView.
Ultra‐flexible electrodes composed of single‐walled carbon nanotubes on a polymeric substrate exhibit excellent transparency, water resistance, and conformability to hairy surfaces. These non‐invasive nanofilms are easily pierced by trichomes, overcoming the structural barriers in plant electrophysiology.
Yusuke Hori, Tatsuhiro Horii, Shinji Masuda, Toshinori Fujie   +3 more
wiley   +1 more source

Hyperpolarization of Nitrile Compounds Using Signal Amplification by Reversible Exchange

Molecules, 2020
Signal Amplification by Reversible Exchange (SABRE), a hyperpolarization technique, has been harnessed as a powerful tool to achieve useful hyperpolarized materials by polarization transfer from parahydrogen.
Sarah Kim, Sein Min, Heelim Chae, Hye Jin Jeong, Sung Keon Namgoong, Sangwon Oh, Keunhong Jeong   +6 more
doaj   +1 more source

Periodic solutions and refractory periods in the soliton theory for nerves and the locust femoral nerve

, 2010
Close to melting transitions it is possible to propagate solitary electromechanical pulses which reflect many of the experimental features of the nerve pulse including mechanical dislocations and reversible heat production.
Abbott, Andersen, Andrei Ludu, Andrew D. Jackson, Coillot, Cole, Ebel, Edgar Villagran Vargas, Eichmann, Evans, FitzHugh, Halstenberg, Halstenberg, Heimburg, Heimburg, Heimburg, Heimburg, Heimburg, Heimburg, Heitler, Hodgkin, Hodgkin, Howarth, Howarth, Hustert, Iwasa, Iwasa, Kaufmann, Kobatake, Lautrup, Mitaku, Mücke, Nagumo, Peter Gumrich, Reinhold Hustert, Remoissenet, Ritchie, Ruiz-Sanz, Schrader, Tasaki, Tasaki, Tasaki, Tasaki, Tasaki, Thomas Heimburg, Wilke, Wilke   +46 more
core   +1 more source

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

Advanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková, Jan Švec, Marie Jakešová, Jiří Ehlich, Imrich Gablech, Eric Daniel Głowacki   +5 more
wiley   +1 more source

Assessing Therapeutic Efficacy in Real-time by Hyperpolarized Magnetic Resonance Metabolic Imaging

Cells, 2019
Precisely measuring tumor-associated alterations in metabolism clinically will enable the efficient assessment of therapeutic responses. Advances in imaging technologies can exploit the differences in cancer-associated cell metabolism as compared to ...
Prasanta Dutta, Travis C. Salzillo, Shivanand Pudakalakatti, Seth T. Gammon, Benny A. Kaipparettu, Florencia McAllister, Shawn Wagner, Daniel E. Frigo, Christopher J. Logothetis, Niki M. Zacharias, Pratip K. Bhattacharya   +10 more
doaj   +1 more source