Results 121 to 130 of about 61,022 (308)

Longitudinal 1H and 129Xe Lung MRI in Patients With Post‐COVID Residual Lung Abnormalities

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background It is unclear how lung function may recover in patients with residual lung abnormalities (RLAs) following COVID‐19 pneumonia. Purpose To evaluate lung function trends over time in patients with RLAs following hospitalization due to COVID‐19. Study Type Prospective, multicenter longitudinal cohort study.
Laura C. Saunders, Guilhem J. Collier, Laurie J. Smith, Ho‐Fung Chan, Paul J. C. Hughes, Scarlett Strickland, Lotta Gustafsson, Thomas Newman, Megan Plowright, Zoë Gabriel, Lily M. Pearce, James T. Grist, Kher Lik Ng, Arthur Harrison, Charlotte E. Bolton, Jody Bray, Helen Marshall, Graham Norquay, Alberto M. Biancardi, Jimmy E. Ball, Neil J. Stewart, Kevin M. Johnson, Andrew J. Swift, Smitha Rajaram, John Blaikley, Stefan Stanel, Paul J. Collini, Gary H. Mills, Rod Lawson, Jonathan Brooke, Amanda T. Goodwin, Iain D. Stewart, Ling‐Pei Ho, Joseph Jacob, Thomas Meersmann, Galina E. Pavlovskaya, Fergus Gleeson, Ian P. Hall, Gisli Jenkins, Jim M. Wild, A. A. Roger Thompson, on behalf of the UK‐ILD consortium   +41 more
wiley   +1 more source

Over 50 % 1H and 13C Polarization for Generating Hyperpolarized Metabolites—A para‐Hydrogen Approach

ChemistryOpen, 2018
para‐Hydrogen‐induced polarization (PHIP) is a method to rapidly generate hyperpolarized compounds, enhancing the signal of nuclear magnetic resonance (NMR) experiments by several thousand‐fold.
Dr. Sergey Korchak, Dr. Salvatore Mamone, Dr. Stefan Glöggler   +2 more
doaj   +1 more source

Enabling Quantitative Benchtop 13C NMR Spectroscopy in Fast Continuous Flow

Magnetic Resonance in Chemistry, EarlyView.
Paramagnetic relaxation enhancement (PRE) accelerates polarization buildup in continuous‐flow benchtop 13$$ {}^{13} $$C NMR spectroscopy by the use of an immobilized PRE agent. By combining PRE with PENDANT polarization transfer, weak 13$$ {}^{13} $$C signals are enhanced even at high flow rates, enabling robust quantitative analysis of solvent ...
Sarah Mross, Hans Hasse, Kerstin Münnemann   +2 more
wiley   +1 more source

A Static Phantom for Harmonization of Hyperpolarized [1–13C]Pyruvate Metabolic Magnetic Resonance Imaging

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and characterize a static, reusable 13C phantom designed to assess and support the harmonization of MRI setups used for hyperpolarized (HP) [1‐13C]pyruvate imaging. Methods The phantom was designed as a 200‐mm‐diameter polycarbonate sphere filled with 8M natural abundance urea and incorporating distinct modules for assessing
Kristina P. Jacobsen, Ingeborg S. Skre, Rie B. Olin, Mathilde H. Lerche   +3 more
wiley   +1 more source

Atlas of Brain Glucose Metabolism Using Deuterium Metabolic Imaging at 3 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Deuterium metabolic imaging (DMI) offers noninvasive magnetic resonance imaging (MRI)–based assessment of metabolism in vivo, making it a relevant paraclinical tool for diseases with neurological metabolic alterations. This study aimed to establish a normative reference atlas of brain glucose metabolism accounting for age and sex ...
Kamilla K. Trosborg, Nichlas V. Christensen, Malene Aastrup, Nikolaj Bøgh, Janne K. Mortensen, Hanne Gottrup, Per Borghammer, Mattias H. Kristensen, Esben S. S. Hansen, Sofie H. Christensen, Jack J. Miller, Rolf F. Schulte, Michael Vaeggemose, Lotte B. Bertelsen, Christoffer Laustsen   +14 more
wiley   +1 more source

SAMBADENA Hyperpolarization of 13C‐Succinate in an MRI: Singlet‐Triplet Mixing Causes Polarization Loss

ChemistryOpen, 2019
The signal enhancement provided by the hyperpolarization of nuclear spins of biological molecules is a highly promising technique for diagnostic imaging.
Stephan Berner, Andreas B. Schmidt, Mirko Zimmermann, Dr. Andrey N. Pravdivtsev, Dr. Stefan Glöggler, Prof. Dr. Dr. h.c. Jürgen Hennig, PD Dr. Dominik von Elverfeldt, Prof. Dr. Jan‐Bernd Hövener   +7 more
doaj   +1 more source

Efficient Parahydrogen Induced 13C Hyperpolarization on a Microfluidic Device

We show the direct production and detection of 13C-hyperpolarized fumarate by parahydrogen-induced polarization (PHIP) in a microfluidic Lab-on-a-Chip (LoC) device and achieve 8.5% 13C polarization.
Marcel, Utz, Laurynas, Dagys, Malcolm, Levitt, Sylwia, Barker   +3 more
core   +1 more source

TRH-induced membrane hyperpolarization in rat clonal anterior pituitary cells

, 1985
Thyrotropin-releasing hormone (TRH) induces biphasic membrane potential changes, a transient hyperpolarization followed by a prolonged enhancement of the generation of action potentials in the clonal GH3 pituitary cell.
S. Ozawa
core   +1 more source

Rapid Hyperpolarization and Purification of the Metabolite Fumarate in Aqueous Solution

, 2020
Hyperpolarized fumarate is a promising agent for carbon-13 magnetic resonance metabolic imaging of cellular necrosis. Molecular imaging applications require nuclear hyperpolarization to attain sufficient signal strength.
Kerstin, Münnemann, Francesca, Reineri, Gerd, Buntkowsky, John W., Blanchard, Silvio, Aime, Danila, Barskiy, Eleonora, Cavallari, Stephan, Knecht, Peter, Blümler, Dmitry, Budker, Erik, van Dyke, James, Eills, Malcolm H., Levitt, Laurynas, Dagys, Maksim, Tsukanov, Bea, Bliemel, Alexander, Pines   +16 more
core   +1 more source

A Modified Balanced Steady State Free Precession Sequence for Overhauser Magnetic Resonance Imaging

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Low‐ and ultralow‐field magnetic resonance imaging (ULF MRI) have inherently low signal‐to‐noise ratio (SNR) by design. Overhauser dynamic nuclear polarization (ODNP) stands out as an effective solution for continuous signal enhancement.
Kai Buckenmaier, Friedemann Bullinger, Georgiy Alekseevich Solomakha, Marcel Schneider, Jörn Engelmann, Philipp Pohlmann, Pavel Povolni, Laura Kuebler, André Ferreira Martins, Klaus Scheffler   +9 more
wiley   +1 more source