Results 111 to 120 of about 61,022 (308)

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

open access: yesEpilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson   +2 more
wiley   +1 more source

Hyperpolarized Renal Magnetic Resonance Imaging: Potential and Pitfalls

open access: yesFrontiers in Physiology, 2016
The introduction of dissolution dynamic nuclear polarization (d-DNP) technology has enabled a new paradigm for renal imaging investigations. It allows standard magnetic resonance imaging complementary renal metabolic and functional fingerprints within ...
Christoffer eLaustsen
doaj   +1 more source

Lack of Bradykinin-lnduced Smooth Muscle Cell Hyperpolarization despite Heterocellular Dye Coupling and Endothelial Cell Hyperpolarization in Porcine Ciliary Artery

open access: yes, 1997
In porcine coronary artery, bradykinin-induced endothelium-dependent vasodilatations are associated with simultaneous endothelium as well as endothelium-dependent smooth muscle cell (SMC) hyperpolarizations.
Beny, Jean-Louis   +2 more
core   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Viscosity effects on optically generated electron and nuclear spin hyperpolarization

open access: yes, 2020
Spin hyperpolarization can dramatically increase signal intensities in magnetic resonance experiments, providing either improved bulk sensitivity or additional spectroscopic detail through selective enhancements.
Cheney, Daniel   +3 more
core   +1 more source

Bio‐inspired artificial retina with receptive fields for in‐sensor multiply‐and‐accumulate operations

open access: yesInfoMat, EarlyView.
We developed a bio‐inspired artificial retina in which curved artificial receptive fields composed of perovskite photoconductors perform multiply‐and‐accumulate operations through in‐sensor computing. This architecture simultaneously realized the structural efficiency of human eyes (compact single‐lens imaging system) and functional advantages of ...
Jisang Ha   +8 more
wiley   +1 more source

Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver   +11 more
wiley   +1 more source

Ultrasensitive 129Xe Magnetic Resonance Imaging: From Clinical Monitoring to Molecular Sensing

open access: yesAdvanced Science
Magnetic resonance imaging (MRI) is a cornerstone technology in clinical diagnostics and in vivo research, offering unparalleled visualization capabilities.
Yuqi Yang   +7 more
doaj   +1 more source

Solvent effects in hyperpolarization of 15N nuclei in [15N3]metronidazole and [15N3]nimorazole antibiotics via SABRE-SHEATH

open access: yes
Metronidazole and nimorazole are antibiotics of a nitroimidazole group originally designed for acting on anaerobic bacteria. These antibiotics may be potentially utilized as hypoxia radiosensitizers for the treatment of cancerous tumors ...
Anna P., Yi   +5 more
core   +1 more source

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