Results 11 to 20 of about 129,353 (325)

Parahydrogen‐Based Hyperpolarization for Biomedicine

Angewandte Chemie International Edition, 2018
AbstractMagnetic resonance (MR) is one of the most versatile and useful physical effects used for human imaging, chemical analysis, and the elucidation of molecular structures. However, its full potential is rarely used, because only a small fraction of the nuclear spin ensemble is polarized, that is, aligned with the applied static magnetic field ...
Jan‐Bernd Hövener, Andrey N. Pravdivtsev, Bryce Kidd, C. Russell Bowers, Stefan Glöggler, Kirill V. Kovtunov, Markus Plaumann, Rachel Katz‐Brull, Kai Buckenmaier, Alexej Jerschow, Francesca Reineri, Thomas Theis, Roman V. Shchepin, Shawn Wagner, Pratip Bhattacharya, Niki M. Zacharias, Eduard Y. Chekmenev   +16 more
openaire   +7 more sources

NMR Hyperpolarization Techniques of Gases [PDF]

Chemistry – A European Journal, 2016
AbstractInvited for the cover of this issue is a group of researchers coordinated by E. Y. Chekmenev from Vanderbilt University. The image depicts hyperpolarized Xe‐129 and parahydrogen gases and their MRI applications. Read the full text of the article at 10.1002/chem.201603884.
Danila A. Barskiy, Aaron M. Coffey, Panayiotis Nikolaou, Dmitry M. Mikhaylov, Boyd M. Goodson, Rosa T. Branca, George J. Lu, Mikhail G. Shapiro, Ville‐Veikko Telkki, Vladimir V. Zhivonitko, Igor V. Koptyug, Oleg G. Salnikov, Kirill V. Kovtunov, Valerii I. Bukhtiyarov, Matthew S. Rosen, Michael J. Barlow, Shahideh Safavi, Ian P. Hall, Leif Schröder, Eduard Y. Chekmenev   +19 more
openaire   +7 more sources

Optogenetic Hyperpolarization of Cardiomyocytes Terminates Ventricular Arrhythmia

Frontiers in Physiology, 2019
Cardiac defibrillation to terminate lethal ventricular arrhythmia (VA) is currently performed by applying high energy electrical shocks. In cardiac tissue, electrical shocks induce simultaneously de- and hyperpolarized areas and only depolarized areas ...
Maximilian Funken, Maximilian Funken, Daniela Malan, Philipp Sasse, Tobias Bruegmann, Tobias Bruegmann, Tobias Bruegmann, Tobias Bruegmann   +7 more
doaj   +2 more sources

Hyperpolarization Methods for MRS [PDF]

, 2015
© 2015 John Wiley & Sons, Ltd. This article covers the fundamental principles and practice of NMR hyperpolarization techniques, which are proving useful for in vivo magnetic resonance spectroscopy (MRS) studies of metabolism in animal models, and clinical trials with hyper-enhanced sensitivity.
Goodson, Boyd M., Whiting, Nicholas, Coffey, Aaron M., Nikolaou, Panayiotis, Shi, Fan, Gust, Brogan M., Gemeinhardt, Max E., Shchepin, Roman V., Skinner, Jason G., Birchall, Jonathan R., Barlow, Michael J., Chekmenev, Eduard Y.   +11 more
openaire   +2 more sources

Spin Hyperpolarization in Modern Magnetic Resonance

Chemical Reviews, 2023
Magnetic resonance techniques are successfully utilized in a broad range of scientific disciplines and in various practical applications, with medical magnetic resonance imaging being the most widely known example. Currently, both fundamental and applied
James Eills, D. Budker, S. Cavagnero, E. Chekmenev, S. Elliott, S. Jannin, A. Lesage, Jörg Matysik, T. Meersmann, T. Prisner, J. Reimer, Hanming Yang, I. Koptyug   +12 more
semanticscholar   +1 more source

Enhanced Optical 13C Hyperpolarization in Diamond Treated by High-Temperature Rapid Thermal Annealing [PDF]

, 2020
Methods of optical dynamic nuclear polarization open the door to the replenishable hyperpolarization of nuclear spins, boosting their nuclear magnetic resonance/imaging signatures by orders of magnitude.
Aguilar, A, Ajoy, A, Druga, E, Gierth, M, Krespach, V, Le, S, Lv, X, Meriles, CA, Nirodi, R, Nunn, N, Pines, A, Raghavan, P, Reimer, JA, Shames, AI, Shen, M, Shenderova, O, Torelli, M, Zaitsev, A, Zhao, R   +18 more
core   +1 more source

RNA interference reveals the escape response mechanism of Paramecium to mechanical stimulation

Biophysics and Physicobiology, 2023
In Paramecium, a mechanical stimulus applied to the posterior portion of the cell causes a transient increase in membrane permeability to potassium ions, transiently rendering the membrane in a hyperpolarized state.
Manabu Hori, Takashi Tominaga, Masaki Ishida, Mutsumi Kawano   +3 more
doaj   +1 more source

Optical Dynamic Nuclear Polarization of ¹³C Spins in Diamond at a Low Field with Multi-Tone Microwave Irradiation

Molecules, 2022
Majority of dynamic nuclear polarization (DNP) experiments have been requiring helium cryogenics and strong magnetic fields for a high degree of nuclear polarization. In this work, we instead demonstrate an optical hyperpolarization of naturally abundant
Vladimir V. Kavtanyuk, Hyun Joon Lee, Sangwon Oh, Keunhong Jeong, Jeong Hyun Shim   +4 more
doaj   +1 more source

Pilot Quality-Assurance Study of a Third-Generation Batch-Mode Clinical-Scale Automated Xenon-129 Hyperpolarizer

Molecules, 2022
We present a pilot quality assurance (QA) study of a clinical-scale, automated, third-generation (GEN-3) 129Xe hyperpolarizer employing batch-mode spin-exchange optical pumping (SEOP) with high-Xe densities (50% natural abundance Xe and 50% N2 in ~2.6 ...
Jonathan R. Birchall, Md Raduanul H. Chowdhury, Panayiotis Nikolaou, Yuri A. Chekmenev, Anton Shcherbakov, Michael J. Barlow, Boyd M. Goodson, Eduard Y. Chekmenev   +7 more
doaj   +1 more source

Signaling Roleplay between Ion Channels during Mammalian Sperm Capacitation

Biomedicines, 2023
In order to accomplish their primary goal, mammalian spermatozoa must undergo a series of physiological, biochemical, and functional changes crucial for the acquisition of fertilization ability.
Filip Benko, Dana Urminská, Michal Ďuračka, Eva Tvrdá   +3 more
doaj   +1 more source