Results 31 to 40 of about 88,078 (299)
Hyperpolarized NMR Probes for Biological Assays
Sensors, 2014 During the last decade, the development of nuclear spin polarization enhanced (hyperpolarized) molecular probes has opened up new opportunities for studying the inner workings of living cells in real time.
Sebastian Meier +3 more
doaj +1 more source
Adenosine, ‘pertussis-sensitive’ G-proteins, and K+ conductance in central mammalian neurones under energy deprivation [PDF]
, 1989 There is a striking similarity between the effects of adenosine and of hypoxia or glucose depletion on membrane potential and conductance of hippocampal neurones in tissue slices of rat brain.
A. Spuler +15 more
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Vasodilation by Hyperpolarization [PDF]
Hypertension, 2006 Clinical assessment of human vascular endothelial function in vivo involves use of specific antagonists such as l-N G monomethyl arginine (l-NMMA) and cyclooxygenase inhibition to establish the contribution of NO and prostaglandins, respectively, to either resting vascular tone, agonist-stimulated vasodilation, or physiological and metabolic ...
Arshed A. Quyyumi, Muhiddin Ozkor
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Hyperpolarization and the endothelium
Current Opinion in Physiology, 2023 The ability of vascular endothelial cells to generate and conduct membrane hyperpolarization is a critical integrative mechanism controlling local blood flow and systemic blood pressure. This mechanism is particularly apparent in the microcirculation.
Garland, CJ, Dora, KA
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Frontiers in Oncology, 2020 Nuclear Magnetic Resonance allows the non-invasive detection and quantitation of metabolites to be carried out in cells and tissues. This means that that metabolic changes can be revealed without the need for sample processing and the destruction of the ...
Eleonora Cavallari +5 more
doaj +1 more source
Essential role of CFTR in PKA-dependent phosphorylation, alkalinization, and hyperpolarization during human dperm capacitation [PDF]
, 2017 Mammalian sperm require to spend a limited period of time in the female reproductive tract to become competent to fertilize in a process called capacitation.
Austin +63 more
core +1 more source
NMR Hyperpolarization Techniques of Gases [PDF]
Chemistry – A European Journal, 2016 AbstractInvited for the cover of this issue is a group of researchers coordinated by E. Y. Chekmenev from Vanderbilt University. The image depicts hyperpolarized Xe‐129 and parahydrogen gases and their MRI applications. Read the full text of the article at 10.1002/chem.201603884.
Danila A. Barskiy +19 more
openaire +5 more sources
Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State
Metabolites, 2021 Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accomplished
Mukundan Ragavan +3 more
doaj +1 more source
Room temperature "optical nanodiamond hyperpolarizer": Physics, design, and operation. [PDF]
, 2020 Dynamic Nuclear Polarization (DNP) is a powerful suite of techniques that deliver multifold signal enhancements in nuclear magnetic resonance (NMR) and MRI.
Aguilar, A +14 more
core
Effects of cromakalim (BRL 34915) on potassium conductances in CA3 neurons of the guinea-pig hippocampus in vitro [PDF]
, 1989 The action of the potassium channel activator, cromakalim (BRL 34915), on membrane potential, input resistance and current-voltage-relationship of CA3 neurons in a slice preparation of the guinea-pig hippocampus was investigated by means of intracellular
Alzheimer, Christian +2 more
core +1 more source