Results 51 to 60 of about 61,022 (308)
Relayed Hyperpolarization for Zero-Field Nuclear Magnetic Resonance
, 2022 Zero- to ultralow-field nuclear magnetic resonance (ZULF NMR) is a rapidly developing form of spectroscopy that drastically reduces the size and expense of portable devices with NMR capabilities. However, signal acquisition still requires a mechanism for
Yinan, Hu +6 more
core +1 more source
Advanced Science, 2023 Amino acids (AAs) and ammonia are metabolic markers essential for nitrogen metabolism and cell regulation in both plants and humans. NMR provides interesting opportunities to investigate these metabolic pathways, yet lacks sensitivity, especially in case
Ewoud Vaneeckhaute +4 more
doaj +1 more source
Simple device for dissolution and sample transfer for applications in spin-hyperpolarization
, 2018 Rapid dissolution and transfer of samples are crucial steps in hyperpolarization methods such as dissolution dynamic nuclear polarization (dDNP) and quantum-rotor-induced polarization (QRIP).
Jannik Knoche (6008336) +4 more
core +1 more source
Interfacing Liquid State Hyperpolarization Methods with NMR Instrumentation
Journal of Magnetic Resonance Open, 2022 Advances in liquid state hyperpolarization methods have enabled new applications of high-resolution NMR spectroscopy. Utilizing strong signal enhancements from hyperpolarization allows performing NMR spectroscopy at low concentration, or with high time ...
Pierce Pham +3 more
doaj +1 more source
Synthetic Studies Toward ［1-13C］Pyruvate
Journal of Isotopes, 2023 Magnetic resonance imaging (MRI) is limited in clinical application due to its low sensitivity. Hyperpolarization technology overcomes this limitation by enhancing molecular MRI signal.
QING Jing;JIA Xuelei;CHEN Kai;DAI Desheng;LI Guowei
doaj +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Journal of Biological Dynamics, 2021 The dynamic mechanism of a whole-cell model containing electrical signalling and two-compartment Ca $ ^{2+} $ signalling in gonadotrophs is investigated.
Xiaowen Xiong, Yanqiu Li, Dongmei Zheng
doaj +1 more source
, 2023 Carbon-13 hyperpolarized pyruvate is about to become the next-generation contrast agent for molecular magnetic resonance imaging of cancer and other diseases.
Laurynas, Dagys +10 more
core +1 more source
Toward C13 hyperpolarized biomarkers produced by thermal mixing with hyperpolarized X129e [PDF]
The Journal of Chemical Physics, 2009 The C13 NMR signal of acetic acid 1-C13-AcH is enhanced by polarization transfer from hyperpolarized X129e using a thermal mixing procedure. 1-C13-AcH acid and hyperpolarized X129e are mixed as gases to disperse X129e in the acetic acid. The mixture is frozen with liquid N2 at 0.5 T.
Natalia, Lisitza +5 more
openaire +2 more sources
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source