Results 41 to 50 of about 61,022 (308)
NMR Hyperpolarization Techniques of Gases [PDF]
AbstractInvited for the cover of this issue is a group of researchers coordinated by E. Y. Chekmenev from Vanderbilt University. The image depicts hyperpolarized Xe‐129 and parahydrogen gases and their MRI applications. Read the full text of the article at 10.1002/chem.201603884.
Danila A. Barskiy +19 more
openaire +5 more sources
Hyperpolarized NMR Probes for Biological Assays
During the last decade, the development of nuclear spin polarization enhanced (hyperpolarized) molecular probes has opened up new opportunities for studying the inner workings of living cells in real time.
Sebastian Meier +3 more
doaj +1 more source
Nuclear Magnetic Resonance allows the non-invasive detection and quantitation of metabolites to be carried out in cells and tissues. This means that that metabolic changes can be revealed without the need for sample processing and the destruction of the ...
Eleonora Cavallari +5 more
doaj +1 more source
Photo-SABRE: hyperpolarization of cis-trans photoswitchable molecules by parahydrogen
Over the past decade, azobenzene-based molecular photoswitches have emerged as promising control devices in a range of fields, including chemistry, biology, materials science, physics, energy storage and pharmacology.
Vitaly, Kozinenko +2 more
core +1 more source
Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State
Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accomplished
Mukundan Ragavan +3 more
doaj +1 more source
Vasodilation by Hyperpolarization [PDF]
Clinical assessment of human vascular endothelial function in vivo involves use of specific antagonists such as l-N G monomethyl arginine (l-NMMA) and cyclooxygenase inhibition to establish the contribution of NO and prostaglandins, respectively, to either resting vascular tone, agonist-stimulated vasodilation, or physiological and metabolic ...
Arshed A. Quyyumi, Muhiddin Ozkor
openaire +1 more source
Hyperpolarizing DNA Nucleobases via NMR Signal Amplification by Reversible Exchange
The present work investigates the potential for enhancing the NMR signals of DNA nucleobases by parahydrogen-based hyperpolarization. Signal amplification by reversible exchange (SABRE) and SABRE in Shield Enables Alignment Transfer to Heteronuclei ...
Bryce E. Kidd +10 more
doaj +1 more source
Activity-dependent excitability changes in normal and demyelinated rat spinal root axons [PDF]
Myelinated nerve fibres with a reduced safety factor for conduction due to demyelination are easily blocked by trains of impulses. To find out why, in vivo recordings from rat ventral root fibres demyelinated with diphtheria toxin have been supplemented ...
H Bostock +3 more
core +1 more source
Singlet-contrast magnetic resonance imaging: unlocking hyperpolarization with metabolism
Hyperpolarization-enhanced magnetic resonance imaging can be used to study biomolecular processes in the body, but typically requires nuclei such as 13C, 15N, or 129Xe due to their long spin‑polarization lifetimes and the absence of a proton‑background ...
Francesca, Reineri +13 more
core +1 more source
Developing hyperpolarized metabolic contrast agents at high field dDNP for large animal research
Dissolution Dynamic Nuclear Polarization (dDNP) polarizers have achieved high field strengths and large sample volumes. These advancements necessitate new formulations of hyperpolarized metabolic contrast agents (HMCAs) to enable large animal studies ...
Ditte B. Christensen +4 more
doaj +1 more source

