Results 41 to 50 of about 88,078 (299)

Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]

, 2001
The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Ulrich, van Hemmen, J. Leo
core   +5 more sources

Hyperpolarizing DNA Nucleobases via NMR Signal Amplification by Reversible Exchange

Molecules, 2023
The present work investigates the potential for enhancing the NMR signals of DNA nucleobases by parahydrogen-based hyperpolarization. Signal amplification by reversible exchange (SABRE) and SABRE in Shield Enables Alignment Transfer to Heteronuclei ...
Bryce E. Kidd, Max E. Gemeinhardt, Jamil A. Mashni, Jonathan L. Gesiorski, Liana B. Bales, Miranda N. Limbach, Roman V. Shchepin, Kirill V. Kovtunov, Igor V. Koptyug, Eduard Y. Chekmenev, Boyd M. Goodson   +10 more
doaj   +1 more source

Neural mechanisms of social learning in the female mouse [PDF]

, 2017
Social interactions are often powerful drivers of learning. In female mice, mating creates a long-lasting sensory memory for the pheromones of the stud male that alters neuroendocrine responses to his chemosignals for many weeks.
Abraham, Abraham, Arnson, Bakker, Barkai, Barth, Ben-Shaul, Brennan, Brennan, Brennan, Brennan, Brennan, Brennan, Bruce, Burns-Cusato, Caligioni, Castro, Chamero, Clancy, Daoudal, Desai, Dietz, Dulac, Dulac, Fan, Guenthner, Halem, Harvey, Hendrickson, Hull, Hurst, Ichikawa, Isaacson, Kaba, Kaba, Kendrick, Keverne, Kimchi, Lee, Li, Lin, Luo, Lévy, Mak, Margrie, Matsuoka, Matsuoka, Matsuoka, Meeks, Mozzachiodi, Nolan, Nolan, Preston, Reijmers, Reijmers, Ross, Rosser, Sakurai, Shepherd, Shingo, Shpak, Shpak, Stackman, Stowers, Ström, Tachikawa, Takahashi, Tirindelli, Tolokh, Turrigiano, Wallace, Wang, Wang, Wang, Wu, Yassin, Yiu, Young, Zhang, Zhou   +79 more
core   +1 more source

Hyperfine structure and nuclear hyperpolarization observed in the bound exciton luminescence of Bi donors in natural Si [PDF]

, 2010
As the deepest group V donor in Si, Bi has by far the largest hyperfine interaction, and also a large I=9/2 nuclear spin. At zero field this splits the donor ground state into states having total spin 5 and 4, which are fully resolved in the ...
Abrosimov, N. V., Noetzel, N., Riemann, H., Saeedi, K., Sekiguchi, T., Steger, M., Thewalt, M. L. W.   +6 more
core   +1 more source

Signaling from blood vessels to CNS axons through nitric oxide [PDF]

, 2006
Brain function is usually perceived as being performed by neurons with the support of glial cells, the network of blood vessels situated nearby serving simply to provide nutrient and to dispose of metabolic waste.
Bartus, K, Dooldeniya, C, Garthwaite, G, Garthwaite, J, Goodwin, D, Kollb-Sielecka, M, Malcolm, D   +6 more
core   +1 more source

Developing hyperpolarized metabolic contrast agents at high field dDNP for large animal research

Journal of Magnetic Resonance Open
Dissolution Dynamic Nuclear Polarization (dDNP) polarizers have achieved high field strengths and large sample volumes. These advancements necessitate new formulations of hyperpolarized metabolic contrast agents (HMCAs) to enable large animal studies ...
Ditte B. Christensen, Ingeborg S. Skre, Jan Henrik Ardenkjær-Larsen, Magnus Karlsson, Mathilde H. Lerche   +4 more
doaj   +1 more source

Amphiphilic blockers punch through a mutant CLC-0 pore. [PDF]

, 2009
Intracellularly applied amphiphilic molecules, such as p-chlorophenoxy acetate (CPA) and octanoate, block various pore-open mutants of CLC-0. The voltage-dependent block of a particular pore-open mutant, E166G, was found to be multiphasic. In symmetrical
Chen, Tsung-Yu, Zhang, Xiao-Dong
core   +2 more sources

Hyperpolarization Methods for MRS [PDF]

, 2015
© 2015 John Wiley & Sons, Ltd. This article covers the fundamental principles and practice of NMR hyperpolarization techniques, which are proving useful for in vivo magnetic resonance spectroscopy (MRS) studies of metabolism in animal models, and clinical trials with hyper-enhanced sensitivity.
Goodson, Boyd M., Whiting, Nicholas, Coffey, Aaron M., Nikolaou, Panayiotis, Shi, Fan, Gust, Brogan M., Gemeinhardt, Max E., Shchepin, Roman V., Skinner, Jason G., Birchall, Jonathan R., Barlow, Michael J., Chekmenev, Eduard Y.   +11 more
openaire   +1 more source

Reversible Parahydrogen Induced Hyperpolarization of 15N in Unmodified Amino Acids Unraveled at High Magnetic Field

Advanced Science, 2023
Amino acids (AAs) and ammonia are metabolic markers essential for nitrogen metabolism and cell regulation in both plants and humans. NMR provides interesting opportunities to investigate these metabolic pathways, yet lacks sensitivity, especially in case
Ewoud Vaneeckhaute, Jean‐Max Tyburn, James G. Kempf, Johan A. Martens, Eric Breynaert   +4 more
doaj   +1 more source

Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres [PDF]

, 1989
The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as K+ channel openers, on the electrical activity of human skeletal muscle.
Grafe, Peter, Lehmann-Horn, Frank, Spuler, A.   +2 more
core   +1 more source