Results 41 to 50 of about 61,022 (308)

NMR Hyperpolarization Techniques of Gases [PDF]

open access: yesChemistry – A European Journal, 2016
AbstractInvited for the cover of this issue is a group of researchers coordinated by E. Y. Chekmenev from Vanderbilt University. The image depicts hyperpolarized Xe‐129 and parahydrogen gases and their MRI applications. Read the full text of the article at 10.1002/chem.201603884.
Danila A. Barskiy   +19 more
openaire   +5 more sources

Hyperpolarized NMR Probes for Biological Assays

open access: yesSensors, 2014
During the last decade, the development of nuclear spin polarization enhanced (hyperpolarized) molecular probes has opened up new opportunities for studying the inner workings of living cells in real time.
Sebastian Meier   +3 more
doaj   +1 more source

In-vitro NMR Studies of Prostate Tumor Cell Metabolism by Means of Hyperpolarized [1-13C]Pyruvate Obtained Using the PHIP-SAH Method

open access: yesFrontiers in Oncology, 2020
Nuclear Magnetic Resonance allows the non-invasive detection and quantitation of metabolites to be carried out in cells and tissues. This means that that metabolic changes can be revealed without the need for sample processing and the destruction of the ...
Eleonora Cavallari   +5 more
doaj   +1 more source

Photo-SABRE: hyperpolarization of cis-trans photoswitchable molecules by parahydrogen

open access: yes, 2023
Over the past decade, azobenzene-based molecular photoswitches have emerged as promising control devices in a range of fields, including chemistry, biology, materials science, physics, energy storage and pharmacology.
Vitaly, Kozinenko   +2 more
core   +1 more source

Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State

open access: yesMetabolites, 2021
Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accomplished
Mukundan Ragavan   +3 more
doaj   +1 more source

Vasodilation by Hyperpolarization [PDF]

open access: yesHypertension, 2006
Clinical assessment of human vascular endothelial function in vivo involves use of specific antagonists such as l-N G monomethyl arginine (l-NMMA) and cyclooxygenase inhibition to establish the contribution of NO and prostaglandins, respectively, to either resting vascular tone, agonist-stimulated vasodilation, or physiological and metabolic ...
Arshed A. Quyyumi, Muhiddin Ozkor
openaire   +1 more source

Hyperpolarizing DNA Nucleobases via NMR Signal Amplification by Reversible Exchange

open access: yesMolecules, 2023
The present work investigates the potential for enhancing the NMR signals of DNA nucleobases by parahydrogen-based hyperpolarization. Signal amplification by reversible exchange (SABRE) and SABRE in Shield Enables Alignment Transfer to Heteronuclei ...
Bryce E. Kidd   +10 more
doaj   +1 more source

Activity-dependent excitability changes in normal and demyelinated rat spinal root axons [PDF]

open access: yes, 1985
Myelinated nerve fibres with a reduced safety factor for conduction due to demyelination are easily blocked by trains of impulses. To find out why, in vivo recordings from rat ventral root fibres demyelinated with diphtheria toxin have been supplemented ...
H Bostock   +3 more
core   +1 more source

Singlet-contrast magnetic resonance imaging: unlocking hyperpolarization with metabolism

open access: yes, 2020
Hyperpolarization-enhanced magnetic resonance imaging can be used to study biomolecular processes in the body, but typically requires nuclei such as 13C, 15N, or 129Xe due to their long spin‑polarization lifetimes and the absence of a proton‑background ...
Francesca, Reineri   +13 more
core   +1 more source

Developing hyperpolarized metabolic contrast agents at high field dDNP for large animal research

open access: yesJournal of Magnetic Resonance Open
Dissolution Dynamic Nuclear Polarization (dDNP) polarizers have achieved high field strengths and large sample volumes. These advancements necessitate new formulations of hyperpolarized metabolic contrast agents (HMCAs) to enable large animal studies ...
Ditte B. Christensen   +4 more
doaj   +1 more source

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