Results 21 to 30 of about 88,078 (299)
Mapping of Absolute Host Concentration and Exchange Kinetics of Xenon Hyper-CEST MRI Agents
Pharmaceuticals, 2021 Xenon magnetic resonance imaging (MRI) provides excellent sensitivity through the combination of spin hyperpolarization and chemical exchange saturation transfer (CEST).
Martin Kunth +2 more
doaj +1 more source
Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity. [PDF]
, 2017 Membrane potential controls the response of the M2 muscarinic receptor to its ligands. Membrane hyperpolarization increases response to the full agonist acetylcholine (ACh) while decreasing response to the partial agonist pilocarpine.
Chen, I-Shan +2 more
core +1 more source
Imaging Sequences for Hyperpolarized Solids
Molecules, 2020 Hyperpolarization is one of the approaches to enhance Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) signal by increasing the population difference between the nuclear spin states.
Xudong Lv +7 more
doaj +1 more source
Molecules, 2022 Accurate knowledge of the rubidium (Rb) vapor density, [Rb], is necessary to correctly model the spin dynamics of 129Xe-Rb spin-exchange optical pumping (SEOP).
James E. Ball +2 more
doaj +1 more source
Cells, 2022 GABA (gamma-aminobutyric acid) receptors represent the major inhibitory receptors in the nervous system and their inhibitory effects are mediated by the influx of chloride ions that tends to hyperpolarize the resting membrane potential.
Sager Nawafleh +6 more
doaj +1 more source
Applied Sciences, 2021 Irreversible electroporation (IRE) has gained attention for ablation owing to fewer side effects and fast recovery. However, a high current from the applied high voltage can cause muscle contraction. Adding cationic molecules has been introduced to lower
Hong Bae Kim, Seung Jeong, Ku Youn Baik
doaj +1 more source
The chloride channel cystic fibrosis transmembrane conductance regulator (CFTR) controls cellular quiescence by hyperpolarizing the cell membrane during diapause in the crustacean Artemia [PDF]
, 2019 Cellular quiescence, a reversible state in which growth, proliferation, and other cellular activities are arrested, is important for self-renewal, differentiation, development, regeneration, and stress resistance.
Bossier, Peter +10 more
core +1 more source
Hyperpolarized Nanodiamond Surfaces [PDF]
Journal of the American Chemical Society, 2016 The widespread use of nanodiamond as a biomedical platform for drug-delivery, imaging, and sub-cellular tracking applications stems from their non-toxicity and unique quantum mechanical properties. Here, we extend this functionality to the domain of magnetic resonance, by demonstrating that the intrinsic electron spins on the nanodiamond surface can be
Ewa Rej +3 more
openaire +3 more sources
Changes in intracellular ion activities induced by adrenaline in human and rat skeletal muscle [PDF]
, 1988 To study the stimulating effect of adrenaline (ADR) on active Na+/K+ transport we used double-barrelled ion-sensitive micro-electrodes to measure the activities of extracellular K+ (aKe) and intracellular Na+ (aNai) in isolated preparations of rat soleus
A Chinet +29 more
core +1 more source
Metabolites, 2023 Efficient 13C hyperpolarization of ketoisocaproate is demonstrated in natural isotopic abundance and [1-13C]enriched forms via SABRE-SHEATH (Signal Amplification By Reversible Exchange in SHield Enables Alignment Transfer to Heteronuclei).
Isaiah Adelabu +9 more
doaj +1 more source