Results 11 to 20 of about 51,213 (265)
Hyperpolarized para-Ethanol [PDF]
The Journal of Physical Chemistry B, 2015 We show that an imbalance between the populations of singlet (S) and triplet (T) states in pairs of magnetically equivalent spins can be generated by dissolution dynamic nudear polarization: In partly deuterated ethanol ((CD3CH2OD)-C-13), this T/S imbalance can be transferred by cross-relaxation to observable, enhanced signals of protons and coupled C ...
Mammoli, Daniele +6 more
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RNA interference reveals the escape response mechanism of Paramecium to mechanical stimulation
Biophysics and Physicobiology, 2023 In Paramecium, a mechanical stimulus applied to the posterior portion of the cell causes a transient increase in membrane permeability to potassium ions, transiently rendering the membrane in a hyperpolarized state.
Manabu Hori +3 more
doaj +1 more source
Molecules, 2022 Majority of dynamic nuclear polarization (DNP) experiments have been requiring helium cryogenics and strong magnetic fields for a high degree of nuclear polarization. In this work, we instead demonstrate an optical hyperpolarization of naturally abundant
Vladimir V. Kavtanyuk +4 more
doaj +1 more source
Molecules, 2022 We present a pilot quality assurance (QA) study of a clinical-scale, automated, third-generation (GEN-3) 129Xe hyperpolarizer employing batch-mode spin-exchange optical pumping (SEOP) with high-Xe densities (50% natural abundance Xe and 50% N2 in ~2.6 ...
Jonathan R. Birchall +7 more
doaj +1 more source
Signaling Roleplay between Ion Channels during Mammalian Sperm Capacitation
Biomedicines, 2023 In order to accomplish their primary goal, mammalian spermatozoa must undergo a series of physiological, biochemical, and functional changes crucial for the acquisition of fertilization ability.
Filip Benko +3 more
doaj +1 more source
Micro-Slab Coil Design for Hyperpolarized Metabolic Flux Analysis in Multiple Samples
Bioengineering, 2022 Abnormal metabolism is a hallmark of cancer cells. Accumulating evidence suggests that metabolic changes are likely to occur before other cellular responses in cancer cells upon drug treatment.
Geonhui Lee +7 more
doaj +1 more source
Hyperpolarized NMR metabolomics
Current Opinion in Chemical Biology, 2023 Hyperpolarized NMR is a promising approach to address the sensitivity limits of conventional NMR metabolomics approaches, which currently fails to detect minute metabolite concentrations in biological samples. This review describes how tremendous signal enhancement offered by dissolution-dynamic nuclear polarization and parahydrogen-based techniques ...
Ribay, Victor +4 more
openaire +3 more sources
Hyperpolarized Views on the Roles of the Hyperpolarization-Activated Channels in Neuronal Excitability [PDF]
Epilepsy Currents, 2010 Upregulated H-Current in Hyperexcitable CA1 Dendrites after Febrile Seizures. Dyhrfjeld-Johnsen J, Morgan RJ, Csaba Foldy, Soltesz I., Front Cell Neurosci. 2008;2:2. doi:10.3389/neuro.03.002.2008. Somatic recordings from CA1 pyramidal cells indicated a persistent upregulation of the h-current ( I h
Noam, Yoav, Baram, Tallie Z
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Frontiers in Cell and Developmental Biology, 2022 When mammalian spermatozoa are released in the female reproductive tract, they are incapable of fertilizing the oocyte. They need a prolonged exposure to the alkaline medium of the female genital tract before their flagellum gets hyperactivated and the ...
Bertrand de Prelle +2 more
doaj +1 more source
Hyperpolarized MR Imaging: Neurologic Applications of Hyperpolarized Metabolism [PDF]
American Journal of Neuroradiology, 2009 Hyperpolarization is the general term for a method of enhancing the spin-polarization difference of populations of nuclei in a magnetic field. No less than 5 distinct techniques (dynamic nuclear polarization [DNP]; parahydrogen-induced polarization-parahydrogen and synthesis allow dramatically enhanced nuclear alignment [PHIP-PASADENA]; xenon/helium ...
B D, Ross +4 more
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