Results 11 to 20 of about 61,022 (308)

Electrical Pacing of Cardiac Tissue Including Potassium Inward Rectification. [PDF]

open access: yesPLoS ONE, 2015
In this study cardiac tissue is stimulated electrically through a small unipolar electrode. Numerical simulations predict that around an electrode are adjacent regions of depolarization and hyperpolarization.
Suran Galappaththige, Bradley J Roth
doaj   +1 more source

Non-Invasive Analysis of Human Liver Metabolism by Magnetic Resonance Spectroscopy

open access: yesMetabolites, 2021
The liver is a key node of whole-body nutrient and fuel metabolism and is also the principal site for detoxification of xenobiotic compounds. As such, hepatic metabolite concentrations and/or turnover rates inform on the status of both hepatic and ...
John G. Jones
doaj   +1 more source

Magnetic Resonance Imaging and Spectroscopy Methods to Study Hepatic Glucose Metabolism and Their Applications in the Healthy and Diabetic Liver

open access: yesMetabolites, 2022
The liver plays an important role in whole-body glucose homeostasis by taking up glucose from and releasing glucose into the blood circulation. In the postprandial state, excess glucose in the blood circulation is stored in hepatocytes as glycogen.
Ayhan Gursan, Jeanine J. Prompers
doaj   +1 more source

RNA interference reveals the escape response mechanism of Paramecium to mechanical stimulation

open access: yesBiophysics and Physicobiology, 2023
In Paramecium, a mechanical stimulus applied to the posterior portion of the cell causes a transient increase in membrane permeability to potassium ions, transiently rendering the membrane in a hyperpolarized state.
Manabu Hori   +3 more
doaj   +1 more source

Optical Dynamic Nuclear Polarization of 13C Spins in Diamond at a Low Field with Multi-Tone Microwave Irradiation

open access: yesMolecules, 2022
Majority of dynamic nuclear polarization (DNP) experiments have been requiring helium cryogenics and strong magnetic fields for a high degree of nuclear polarization. In this work, we instead demonstrate an optical hyperpolarization of naturally abundant
Vladimir V. Kavtanyuk   +4 more
doaj   +1 more source

Pilot Quality-Assurance Study of a Third-Generation Batch-Mode Clinical-Scale Automated Xenon-129 Hyperpolarizer

open access: yesMolecules, 2022
We present a pilot quality assurance (QA) study of a clinical-scale, automated, third-generation (GEN-3) 129Xe hyperpolarizer employing batch-mode spin-exchange optical pumping (SEOP) with high-Xe densities (50% natural abundance Xe and 50% N2 in ~2.6 ...
Jonathan R. Birchall   +7 more
doaj   +1 more source

Signaling Roleplay between Ion Channels during Mammalian Sperm Capacitation

open access: yesBiomedicines, 2023
In order to accomplish their primary goal, mammalian spermatozoa must undergo a series of physiological, biochemical, and functional changes crucial for the acquisition of fertilization ability.
Filip Benko   +3 more
doaj   +1 more source

Spin Hyperpolarization in Modern Magnetic Resonance

open access: yes, 2022
Magnetic resonance techniques are successfully utilized in a broad range of scientific disciplines and in a number of practical applications, with medical MRI being the most widely-known example. Currently, both fundamental and applied magnetic resonance
Jeffrey A., Reimer   +12 more
core   +1 more source

Micro-Slab Coil Design for Hyperpolarized Metabolic Flux Analysis in Multiple Samples

open access: yesBioengineering, 2022
Abnormal metabolism is a hallmark of cancer cells. Accumulating evidence suggests that metabolic changes are likely to occur before other cellular responses in cancer cells upon drug treatment.
Geonhui Lee   +7 more
doaj   +1 more source

Hyperpolarized para-Ethanol [PDF]

open access: yesThe Journal of Physical Chemistry B, 2015
We show that an imbalance between the populations of singlet (S) and triplet (T) states in pairs of magnetically equivalent spins can be generated by dissolution dynamic nudear polarization: In partly deuterated ethanol ((CD3CH2OD)-C-13), this T/S imbalance can be transferred by cross-relaxation to observable, enhanced signals of protons and coupled C ...
Mammoli, Daniele   +6 more
openaire   +4 more sources

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