Results 31 to 40 of about 129,353 (325)

Capillary K+-sensing initiates retrograde hyperpolarization to locally increase cerebral blood flow

Nature Neuroscience, 2017
Blood flow into the brain is dynamically regulated to satisfy the changing metabolic requirements of neurons, but how this is accomplished has remained unclear. Here we demonstrate a central role for capillary endothelial cells in sensing neural activity
T. Longden, Fabrice Dabertrand, M. Koide, Albert L. Gonzales, N. Tykocki, J. Brayden, David Hill-Eubanks, M. Nelson   +7 more
semanticscholar   +1 more source

Orientation-independent room temperature optical 13C hyperpolarization in powdered diamond [PDF]

Science Advances, 2018
Shining light on diamond particles makes them MRI-“bright,” opening avenues for room temperature hyperpolarized liquids. Dynamic nuclear polarization via contact with electronic spins has emerged as an attractive route to enhance the sensitivity of ...
A. Ajoy, Kristina S. Liu, R. Nazaryan, X. Lv, P. Zangara, B. Safvati, Guoqing Wang, D. Arnold, Grace Li, A. Lin, P. Raghavan, E. Druga, S. Dhomkar, D. Pagliero, J. Reimer, D. Suter, C. Meriles, A. Pines   +17 more
semanticscholar   +1 more source

Changes of intracellular sodium and potassium ion concentrations in frog spinal motoneurons induced by repetitive synaptic stimulation [PDF]

, 1982
A post-tetanic membrane hyperpolarization following repetitive neuronal activity is a commonly observed phenomenon in the isolated frog spinal cord as well as in neurons of other nervous tissues.
Baker, Baylor, Bu¨hrle, Coles, Cordingley, Czeh, Davidoff, G. ten Bruggencate, Grafe, Gu¨ggi, Heinemann, Hofmeier, J. Rimpel, Krnjevic, Kuno, Kuramoto, Lux, M.M. Reddy, Mori, Nakajima, Nicholson, Nicoll, O'Doherty, P. Grafe, Ritchie, Smith, Sonnhof, Sonnhof, Sonnhof, Steiner, Sykova, Tang, Thomas, Vern   +33 more
core   +1 more source

Imaging Sequences for Hyperpolarized Solids

Molecules, 2020
Hyperpolarization is one of the approaches to enhance Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) signal by increasing the population difference between the nuclear spin states.
Xudong Lv, Jeffrey Walton, Emanuel Druga, Raffi Nazaryan, Haiyan Mao, Alexander Pines, Ashok Ajoy, Jeffrey Reimer   +7 more
doaj   +1 more source

Investigating Rubidium Density and Temperature Distributions in a High-Throughput ¹²⁹Xe-Rb Spin-Exchange Optical Pumping Polarizer

Molecules, 2022
Accurate knowledge of the rubidium (Rb) vapor density, [Rb], is necessary to correctly model the spin dynamics of 129Xe-Rb spin-exchange optical pumping (SEOP).
James E. Ball, Jim M. Wild, Graham Norquay   +2 more
doaj   +1 more source

Voltage Sensor Movements during Hyperpolarization in the HCN Channel.

Cell, 2019
The hyperpolarization-activated cyclic nucleotide-gated (HCN) channel is a voltage-gated cation channel that mediates neuronal and cardiac pacemaker activity. The HCN channel exhibits reversed voltage dependence, meaning it closes with depolarization and
Chia-Hsueh Lee, R. MacKinnon
semanticscholar   +1 more source

GABA Receptors Can Depolarize the Neuronal Membrane Potential via Quantum Tunneling of Chloride Ions: A Quantum Mathematical Study

Cells, 2022
GABA (gamma-aminobutyric acid) receptors represent the major inhibitory receptors in the nervous system and their inhibitory effects are mediated by the influx of chloride ions that tends to hyperpolarize the resting membrane potential.
Sager Nawafleh, Abdallah Barjas Qaswal, Aiman Suleiman, Obada Alali, Fuad Mohammed Zayed, Mohammad Abu Orabi Al-Adwan, Mo’ath Bani Ali   +6 more
doaj   +1 more source

Opioids excite dopamine neurons by hyperpolarization of local interneurons

Journal of Neuroscience, 1992
Increased activity of dopamine-containing neurons in the ventral tegmental area is necessary for the reinforcing effects of opioids and other abused drugs.
S. Johnson, R. North
semanticscholar   +1 more source

Preconditioning with Near-Infrared Irradiation to Enhance the Irreversible Electroporation Efficiency in HeLa Cells

Applied Sciences, 2021
Irreversible electroporation (IRE) has gained attention for ablation owing to fewer side effects and fast recovery. However, a high current from the applied high voltage can cause muscle contraction. Adding cationic molecules has been introduced to lower
Hong Bae Kim, Seung Jeong, Ku Youn Baik
doaj   +1 more source

Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]

, 2001
The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Ulrich, van Hemmen, J. Leo
core   +5 more sources