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Age Differences in Pet Sensitization by Pet Ownership [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2021
Objectives The association between pet sensitization and pet ownership remains unclear. Therefore, we aimed to elucidate the association between pet sensitization and pet ownership by age.
Jun Yeon Won   +3 more
doaj   +1 more source

Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19

open access: yesScientific Reports, 2022
COVID-19 can cause acute respiratory distress syndrome, leading to death in many individuals. Evidence of a deleterious role of the innate immune system is accumulating, but the precise mechanisms involved remain unclear.
Marine Peyneau   +12 more
doaj   +1 more source

The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity

open access: yesFrontiers in Immunology, 2021
The immunomodulatory effects of regulatory T cells (Tregs) and co-signaling receptors have gained much attention, as they help balance immunogenic and immunotolerant responses that may be disrupted in autoimmune and infectious diseases.
Yun-Shiuan Olivia Hsu   +43 more
doaj   +1 more source

Update on pathobiology in Stevens-Johnson syndrome and toxic epidermal necrolysis

open access: yesDermatologica Sinica, 2013
Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) are rare but life-threatening severe cutaneous adverse reactions (SCARs), which are mainly induced by a variety of drugs. Once considered to be unpredictable, significant progress has been
Shih-Chi Su, Wen-Hung Chung
doaj   +1 more source

Cytotoxic Proteins and Therapeutic Targets in Severe Cutaneous Adverse Reactions

open access: yesToxins, 2014
Severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN), are rare but life-threatening conditions induced mainly by a variety of drugs.
Shih-Chi Su, Wen-Hung Chung
doaj   +1 more source

Severe edema of the eyes and lips as rare side effects of eye ointment for protection of eyes under general anesthesia -A case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
Patients undergoing non-ocular surgery under general anesthesia may suffer from ocular complications because of the loss of protective reflexes. Simple taping of the eyelids closed, the instillation of ointments into the conjunctival sac, and the use of ...
Sang-Jin Park, In-Seong Kim
doaj   +1 more source

Acute generalized exanthematous pustulosis: A retrospective study of 51 cases in Taiwan

open access: yesDermatologica Sinica, 2014
Background/Objective: Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction characterized by fever and numerous sterile non-follicular pustules.
Yung-Yi Lee, Wen-Hung Chung
doaj   +1 more source

Rituximab Hypersensitivity: From Clinical Presentation to Management

open access: yesFrontiers in Pharmacology, 2020
Rituximab is a chimeric monoclonal antibody (mAb) against CD20 molecule which is expressed on human B cells. It has been used for the treatment of various lymphoid malignancies, lymphoproliferative diseases, and rheumatologic disorders.
Ghada E. Fouda, Sevim Bavbek
doaj   +1 more source

Converter Phenotype: A New Profile That Is Not Exclusive to Taxanes

open access: yesFrontiers in Allergy, 2022
Introduction: Phenotype I hypersensitivity reactions are the most commonly reported drug reactions; however, precision medicine has made it possible to characterize new phenotypes. A recent communication proposed the existence of a “converter phenotype,”
Teodorikez Wilfox Jimenez-Rodriguez   +13 more
doaj   +1 more source

Comparative evaluation of use of diode laser and electrode with and without two dentinal tubule occluding agents in the management of dentinal hypersensitivity: An experimental in vitro study

open access: yesJournal of Indian Society of Periodontology, 2020
Background: The present study aims to assess area of open dentinal tubules by use of diode laser and electrode alone and in combination with hydroxyapatite powder and strontium chloride powder by using the scanning electron microscope (SEM).
Chitra Laxmikant Patil   +1 more
doaj   +1 more source

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