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An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity

open access: yesJournal of Immunology Research, 2018
Drug hypersensitivity may manifest ranging from milder skin reactions (e.g., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced ...
Chun-Bing Chen   +6 more
doaj   +2 more sources

Hypersensitiveness [PDF]

open access: bronzeProceedings of the Royal Society of Medicine, 1912
E. W. Goodall
openalex   +3 more sources

Cough hypersensitivity and chronic cough

open access: yesNature Reviews Disease Primers, 2022
Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat because many pulmonary and extrapulmonary conditions can present with chronic cough, and cough can also be present without any identifiable underlying cause ...
K. Chung   +8 more
semanticscholar   +1 more source

PAINFUL ANTERIOR KNEE SCHWANNOMA: A CASE REPORT [PDF]

open access: yesJournal of IMAB, 2023
Tumors of the peripheral nervous system are classified according to the specific origin of cell differentiation. Schwannomas (neurilemmomas) are benign nerve sheath tumors slowly growing, often solitary, arising from the nerves' Schwann cells that are ...
Stoyan Ivanov, Dimitar Trizlov
doaj   +1 more source

Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19

open access: yesScientific Reports, 2022
COVID-19 can cause acute respiratory distress syndrome, leading to death in many individuals. Evidence of a deleterious role of the innate immune system is accumulating, but the precise mechanisms involved remain unclear.
Marine Peyneau   +12 more
doaj   +1 more source

Hypersensitivity in teeth affected by molar-incisor hypomineralization (MIH)

open access: yesScientific Reports, 2021
Tooth hypersensitivity is a common symptom in patients with molar-incisor hypomineralization (MIH). Therefore, this clinical study aimed to assess potential associations between patient- and tooth-related variables and the intensity of hypersensitivity ...
T. Linner   +5 more
semanticscholar   +1 more source

The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity

open access: yesFrontiers in Immunology, 2021
The immunomodulatory effects of regulatory T cells (Tregs) and co-signaling receptors have gained much attention, as they help balance immunogenic and immunotolerant responses that may be disrupted in autoimmune and infectious diseases.
Yun-Shiuan Olivia Hsu   +43 more
doaj   +1 more source

Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

open access: yesFrontiers in Pharmacology, 2022
Vancomycin is a commonly used antibiotic; however, it can cause life-threatening severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS).
Chuang-Wei Wang   +42 more
doaj   +1 more source

Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2020
Immediate and nonimmediate hypersensitivity reactions to iodinated contrast media (ICM) have been reported to occur in a frequency of about 0.5%‐3% of patients receiving nonionic ICM.
Marta E. Torres   +13 more
semanticscholar   +1 more source

Hypersensitivity pneumonitis [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2006
Hypersensitivity pneumonitis (HP) is a pulmonary disease with symptoms of dyspnea and cough resulting from the inhalation of an antigen to which the subject has been previously sensitized. The incidence of HP is unknown. A population-based study estimated the annual incidence of interstitial lung diseases as 30:100,000 and HP accounted for less than 2%
Cormier Yvon, Lacasse Yves
openaire   +3 more sources

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