Results 151 to 160 of about 3,251 (194)

Temporal Changes in the Contribution of Chronic Disease to Maternal Mortality in the United States

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Increases in maternal age, obesity and other factors have led to an increase in hypertension, diabetes, and other chronic diseases among pregnant women. However, the impact of chronic diseases on maternal mortality has not been adequately studied.
Yasser Sabr   +3 more
wiley   +1 more source

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

open access: yesExperimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee   +8 more
wiley   +1 more source

Advances in the treatment of hepatocellular carcinoma: An overview of the current and evolving therapeutic landscape for clinicians

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is the sixth most common malignancy and the third leading cause of cancer‐related death worldwide. Contemporary advances in systemic and locoregional therapies have led to changes in peer‐reviewed guidelines regarding systemic therapy as well as the possibility of downstaging disease that may enable some patients
Dimitrios Moris   +12 more
wiley   +1 more source

Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 7, July 2025.
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song   +9 more
wiley   +1 more source

The interplay between heart failure and chronic kidney disease

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 7, Page 3568-3582, July 2025.
Abstract Chronic kidney disease (CKD) and heart failure (HF) are two globally prevalent, independent, long‐term conditions, which often coexist in an individual and display a bidirectional yet interconnected relationship. The presence of CKD often leads to the development of HF and vice versa, which propagates the worsening of each disease, reflecting ...
Anuradha Lala   +2 more
wiley   +1 more source

Hepatic Phenotype in NBAS‐Associated Disease: Clinical Course, Prognostic Factors and Outcome in 230 Patients

open access: yesLiver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background and Aims Since described in 2015, NBAS‐associated disease has emerged as an important cause of acute liver failure (ALF) in children. We analysed the variable expression, genotype–phenotype association, outcome and prognostic factors of the hepatic involvement.
Bianca Peters   +32 more
wiley   +1 more source

Clinical Utility of Non‐Invasive Tests for Liver Fibrosis in People Living With Alpha‐1 Antitrypsin Deficiency

open access: yesLiver International, Volume 45, Issue 7, July 2025.
ABSTRACT Severe alpha‐1 antitrypsin deficiency (AATD) is a rare genetic condition characterised by low systemic levels of alpha‐1 antitrypsin due to its retention in the liver. Consequently, it predisposes individuals to the development of chronic obstructive pulmonary disease and liver cirrhosis.
Joost Boeckmans   +4 more
wiley   +1 more source

Remote patient monitoring for managing acute COVID‐19, and mortality and hospital use in Sydney, New South Wales, 2021–22: a retrospective observational cohort study

open access: yesMedical Journal of Australia, Volume 222, Issue 11, Page 550-557, June 2025.
Abstract Objectives To evaluate the influence of remote patient monitoring (RPM) for managing people with acute coronavirus disease 2019 (COVID‐19) on 28‐day mortality and hospital use in Australia. Study design Retrospective observational cohort study; analysis of deterministically linked NSW Notifiable Conditions Information Management System and ...
Myong Gyu Kim   +14 more
wiley   +1 more source

Topics of Interest in Women With Myeloproliferative Neoplasms

open access: yesAmerican Journal of Hematology, Volume 100, Issue S4, Page 74-87, June 2025.
Women with MPN: life‐cycle phases, specific risks, and influencing factors. ABSTRACT Overview Sex and gender have emerged as central modifiers of disease biology, phenotype, and clinical outcomes in myeloproliferative neoplasms (MPNs). This review will uniquely highlight issues affecting women with MPN and articulate their relevant determinants ...
Natasha Szuber   +2 more
wiley   +1 more source

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