Influence of image segmentation on one-dimensional fluid dynamics predictions in the mouse pulmonary arteries [PDF]
, 2019 Computational fluid dynamics (CFD) models are emerging as tools for assisting in diagnostic assessment of cardiovascular disease. Recent advances in image segmentation has made subject-specific modelling of the cardiovascular system a feasible task, which is particularly important in the case of pulmonary hypertension (PH), which requires a combination
arxiv +1 more source
Pulmonary hypertension, pulmonary embolism and COVID-19: A district general hospital experience from the UK. [PDF]
J R Coll Physicians Edinb, 2023 Mahdi N +6 more
europepmc +1 more source
Scientific ReportsTargeted vasopeptide therapies have significantly advanced the management of pulmonary arterial hypertension (PAH). However, due to insufficient preclinical evidence regarding the involvement of the endothelin-1 (ET-1) pathway in chronic thromboembolic ...
Benchenouf Feriel +16 more
doaj +1 more source
International Journal of Cardiology Congenital Heart Disease, 2022 Impaired ventilatory responses during exercise significantly contribute to breathlessness in patients with pulmonary arterial hypertension (PAH). Breathing reserve (BR) at peak exercise during cardiopulmonary exercise testing (CPET), a measure of the ...
Chinthaka B. Samaranayake +8 more
doaj
Case report: Rescue treatment with add-on selexipag in a preterm infant with suprasystemic pulmonary hypertension, pulmonary capillary hemangiomatosis, and isolated pulmonary vein stenosis. [PDF]
Front Cardiovasc Med, 2022 Hasan H +5 more
europepmc +1 more source
The medium-term consequences of a COVID-19 lockdown on lifestyle among Spanish older people with hypertension, pulmonary disease, cardiovascular disease, musculoskeletal disease, depression, and cancer. [PDF]
Epidemiol Health, 2022 Rodríguez-Gómez I +13 more
europepmc +1 more source
HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension
Scientific Reports, 2017 Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with limited therapeutic options. Although exposed to stressful conditions, pulmonary artery (PA) smooth muscle cells (PASMCs) exhibit a “cancer-like” pro-proliferative and anti ...
Olivier Boucherat +13 more
doaj +1 more source
AI-Enabled Accurate Non-Invasive Assessment of Pulmonary Hypertension Progression via Multi-Modal Echocardiography [PDF]
arXivEchocardiographers can detect pulmonary hypertension using Doppler echocardiography; however, accurately assessing its progression often proves challenging. Right heart catheterization (RHC), the gold standard for precise evaluation, is invasive and unsuitable for routine use, limiting its practicality for timely diagnosis and monitoring of pulmonary ...
arxiv
MCMC methods for inference in a mathematical model of pulmonary circulation [PDF]
arXiv, 2018 This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics under normal physiological and pathological conditions.
arxiv
Pulmonary Circulation, 2019 Atrial septal defect (ASD) is one of the most frequent congenital heart diseases (CHD). Up to 10% of adults with an ASD develop pulmonary arterial hypertension (PAH, PAH-CHD) in their lifetime.
Christopher Hohmann +5 more
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