Results 21 to 30 of about 923 (49)

Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses

Frontiers in Oncology, 2020
Moderate hyperthermia at temperatures between 40 and 44°C is a multifaceted therapeutic modality. It is a potent radiosensitizer, interacts favorably with a host of chemotherapeutic agents, and, in combination with radiotherapy, enforces immunomodulation
Niloy R. Datta, H. Petra Kok, Hans Crezee, Udo S. Gaipl, Stephan Bodis   +4 more
doaj   +1 more source

Mild hyperthermia enhances sensitivity of gastric cancer cells to chemotherapy through reactive oxygen species–induced autophagic death

Tumor Biology, 2017
Mild hyperthermia enhances anti-cancer effects of chemotherapy, but the precise biochemical mechanisms involved are not clear. This study was carried out to investigate whether mild hyperthermia sensitizes gastric cancer cells to chemotherapy through ...
Ming-Chen Ba, Hui Long, Shu-Zhong Cui, Yuan-Feng Gong, Zhao-Fei Yan, Shuai Wang, Yin-Bing Wu   +6 more
doaj   +1 more source

The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride

Frontiers in Molecular Neuroscience, 2022
Methamphetamine (METH) abuse causes irreversible damage to the central nervous system and leads to psychiatric symptoms including depression. Notably, METH-induced hyperthermia is a crucial factor in the development of these symptoms, as it aggravates ...
Xintao Wang, Xintao Wang, Xintao Wang, Bonan Tong, Bonan Tong, Bonan Tong, Rongji Hui, Rongji Hui, Rongji Hui, Congcong Hou, Congcong Hou, Congcong Hou, Zilu Zhang, Ludi Zhang, Ludi Zhang, Ludi Zhang, Bing Xie, Bing Xie, Bing Xie, Zhiyu Ni, Bin Cong, Bin Cong, Bin Cong, Chunling Ma, Chunling Ma, Chunling Ma, Di Wen, Di Wen, Di Wen   +28 more
doaj   +1 more source

Histone deacetylase inhibitors sensitize lung cancer cells to hyperthermia: involvement of Ku70/SirT-1 in thermo-protection.

PLoS ONE, 2014
This study describes the sensitization mechanism to thermal stress by histone deacetylase inhibitors (HDACIs) in lung cancer cells and shows that Ku70, based on its acetylation status, mediates the protection of lung cancer from hyperthermia (42.5°C, 1-6
Mohamed K Hassan, Hidemichi Watari, Alaa-Eldin Salah-Eldin, Ahmed S Sultan, Zainab Mohamed, Yoichiro Fujioka, Yusuke Ohba, Noriaki Sakuragi   +7 more
doaj   +1 more source

Suppressive effects of a transient receptor potential melastatin 8 (TRPM8) agonist on hyperthermia-induced febrile seizures in infant mice

Frontiers in Pharmacology, 2023
Background: Febrile seizures (FSs) are the most frequent type of seizures in infancy and childhood. Epileptiform discharges (EDs) on electroencephalogram at the time of first FS recurrence can increase the risk of epilepsy development.
Hiroshi Moriyama, Sadahiro Nomura, Sadahiro Nomura, Hirochika Imoto, Hirochika Imoto, Fumiaki Oka, Yuichi Maruta, Naomasa Mori, Natsumi Fujii, Michiyasu Suzuki, Hideyuki Ishihara   +10 more
doaj   +1 more source

Inducible protective processes in animal systems XV: Hyperthermia enhances the Ethyl methanesulfonate induced adaptive response in meiotic cells of grasshopper Poecilocerus pictus

Egyptian Journal of Medical Human Genetics, 2016
Purpose: To understand the role of hyperthermia in adaptive response, Ethyl methanesulfonate (EMS) an anticarcinogenic agent, adapted meiotic cells of Poecilocerus pictus was used.
R. Venu, H.P. Gurushankara, B.B.D. Khalandar, V. Vasudev   +3 more
doaj   +1 more source

Decrease in MAP3Ks expression enhances the cell death caused by hyperthermia

International Journal of Hyperthermia, 2022
Purpose Hyperthermia is a promising anticancer treatment modality. However, the molecular mechanism underlying the thermal sensitivity of tumor cells is largely unknown.
Atsushi Enomoto, Takemichi Fukasawa, Hiroshi Terunuma, Keiichi Nakagawa, Ayumi Yoshizaki, Shinichi Sato, Kiyoshi Miyagawa   +6 more
doaj   +1 more source

Enhancing Gastric Cancer Therapeutic Efficacy through Synergistic Cotreatment of Linderae Radix and Hyperthermia in AGS Cells

Biomedicines, 2023
Gastric cancer remains a global health threat, particularly in Asian countries. Current treatment methods include surgery, chemotherapy, and radiation therapy.
Chae-Ryeong Ahn, Seung-Ho Baek
doaj   +1 more source

Graphene Oxide Nanosheets for Localized Hyperthermia—Physicochemical Characterization, Biocompatibility, and Induction of Tumor Cell Death

Cells, 2020
Background: The main goals of cancer treatment are not only to eradicate the tumor itself but also to elicit a specific immune response that overcomes the resistance of tumor cells against chemo- and radiotherapies. Hyperthermia was demonstrated to chemo-
Malgorzata J. Podolska, Alexandre Barras, Christoph Alexiou, Benjamin Frey, Udo Gaipl, Rabah Boukherroub, Sabine Szunerits, Christina Janko, Luis E. Muñoz   +8 more
doaj   +1 more source

Ponciri Fructus Immatarus Sensitizes the Apoptotic Effect of Hyperthermia Treatment in AGS Gastric Cancer Cells through ROS-Dependent HSP Suppression

Biomedicines, 2023
Gastric cancer has been associated with a high incidence and mortality, accompanied by a poor prognosis. Given the limited therapeutic options to treat gastric cancer, alternative treatments need to be urgently developed.
Chae Ryeong Ahn, Hyo In Kim, Jai-Eun Kim, In Jin Ha, Kwang Seok Ahn, Jinbong Park, Young Woo Kim, Seung Ho Baek   +7 more
doaj   +1 more source