Results 11 to 20 of about 166,449 (252)
Korean Journal of Anesthesiology, 2012 Malignant hyperthermia (MH) is an uncommon, life-threatening pharmacogenetic disorder of the skeletal muscle. It presents as a hypermetabolic response in susceptible individuals to potent volatile anesthetics with/without depolarizing muscle relaxants; in rare cases, to stress from exertion or heat stress. Susceptibility to malignant hyperthermia (MHS)
Bandschapp, O., Girard, T.
+10 more sources
World Journal of Biology Pharmacy and Health Sciences, 2023 There is scientific support for the concept of a temperature set point that is, maintenance of an optimal temperature for the metabolic processes that life depends on Nervous activity in the preoptic-anterior hypothalamus of the brain triggers heat losing (sweating, etc.) or heat generating (shivering and muscle contraction, etc.) activities through ...
G. Ushakiran +4 more
openaire +1 more source
Orphanet Journal of Rare Diseases, 2007 Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, in humans, to stresses such as vigorous exercise and heat.
Pollock Neil +4 more
openaire +3 more sources
Evidence for Two Modes of Synergistic Induction of Apoptosis by Mapatumumab and Oxaliplatin in Combination with Hyperthermia in Human Colon Cancer Cells [PDF]
, 2013 Colorectal cancer is the third leading cause of cancer-related mortality in the world-- the main cause of death from colorectal cancer is hepatic metastases, which can be treated with isolated hepatic perfusion (IHP).
A Jemal +52 more
core +6 more sources
Effect of hyperthermia on prognosis after acute ischemic stroke [PDF]
, 2009 <p><b>Background and Purpose:</b> Experimental studies have shown that hyperthermia is a determinant of poor outcome after ischemic stroke.
Kamruzzaman, A. +4 more
core +1 more source
Cell line-specific efficacy of thermoradiotherapy in human and canine cancer cells in vitro [PDF]
, 2019 Objective Aims were to investigate sensitivity of various human and canine cancer cell lines to hyperthermia and the influence of particular treatment conditions, and to analyze the DNA-damage response and mode of cell death in cell line radiosensitized
Nytko, Katarzina J. +4 more
core +2 more sources
Hyperthermia combined with chemotherapy - Biological rationale, clinical application, and treatment results [PDF]
, 1999 There is substantial evidence from preclinical data that the antitumor cytotoxicity of selected chemotherapeutic agents either alone or combined with radiation can be enhanced by appropriate heat exposure (40-44 degrees C) of cells or tumor tissues ...
Issels, Rolf-Dieter
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Potentiation of the abscopal effect by modulated electro-hyperthermia in locally advanced cervical cancer patients [PDF]
, 2020 Background: A Phase III randomized controlled trial investigating the addition of modulated electro-hyperthermia (mEHT) to chemoradiotherapy for locally advanced cervical cancer patients is being conducted in South Africa (Human Research Ethics Committee
Ayeni, Olusegun +4 more
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Predictive value of SAR based quality indicators for head and neck hyperthermia treatment quality
International Journal of Hyperthermia, 2019 Purpose: Hyperthermia treatment quality determines treatment effectiveness as shown by the clinically derived thermal-dose effect relations. SAR based optimization factors are used as possible surrogate for temperature, since they are not affected by ...
Gennaro G. Bellizzi +5 more
doaj +1 more source
Hyperthermia treatment of tumors by mesenchymal stem cell-delivered superparamagnetic iron oxide nanoparticles. [PDF]
, 2015 Magnetic hyperthermia - a potential cancer treatment in which superparamagnetic iron oxide nanoparticles (SPIONs) are made to resonantly respond to an alternating magnetic field (AMF) and thereby produce heat - is of significant current interest. We have
Janes, SM +7 more
core +2 more sources