Results 31 to 40 of about 172,058 (341)

Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer - Preliminary results [PDF]

, 2003
Background: The local recurrence rate of colorectal cancer has been significantly reduced due to the use of combined radiochemotherapy. Despite this improvement regarding locally advanced tumour recurrences, the treatment strategy for pre-treated ...
Abdel-Rahman, Sultan, Dühmke, Eckhart, Ertl-Wagner, Birgit, Issels, Rolf-Dieter, Krych, M., Pachmann, S., Schaffer, Moshe, Schaffer, Pamela Manuela   +7 more
core   +1 more source

Profile of malignant hyperthermia susceptibility reports confirmed with muscular contracture test in Brazil [PDF]

Revista Brasileira de Anestesiologia
Background and objectives: Malignant hyperthermia is an autosomal dominant hypermetabolic pharmacogenetic syndrome, with a mortality rate of 10%–20%, which is triggered by the use of halogenated inhaled anesthetics or muscle relaxant succinylcholine. The
Helga Cristina Almeida da Silva, Gisele Ferreira, Gislene Rodrigues, Joilson Moura dos Santos, Pamela Vieira Andrade, Alexandre Hortense, Marcelo Vaz Perez, José Luiz Gomes do Amaral   +7 more
doaj   +3 more sources

Multipotent mesenchymal stromal cells are sensitive to thermic stress – potential implications for therapeutic hyperthermia

International Journal of Hyperthermia, 2020
Purpose Hyperthermia demonstrated clinical efficacy in multimodal cancer treatment. Multipotent mesenchymal stromal cells (MSCs) as part of the tumor-supporting stroma modulate tumor response and tissue regeneration after hyperthermia.
Alexander Rühle, Andreas Thomsen, Rainer Saffrich, Maren Voglstätter, Birgit Bieber, Tanja Sprave, Patrick Wuchter, Peter Vaupel, Peter E. Huber, Anca-Ligia Grosu, Nils H. Nicolay   +10 more
doaj   +1 more source

A Rare Case of Drug Interaction Presenting as Perioperative Hyperthermia in a Patient Presenting for Neurosurgery

Journal of Neuroanaesthesiology and Critical Care, 2022
Perioperative hyperthermia has many differential diagnoses. This case report describes the rare causation of perioperative hyperthermia in a patient presenting for epilepsy surgery.
Sapna Suresh, Ajay P. Hrishi, Manikandan Sethuraman   +2 more
doaj   +1 more source

The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis. [PDF]

PLoS ONE, 2013
A combination of hyperthermia with radiotherapy and chemotherapy for various solid tumors has been practiced clinically. However, hyperthermic therapy has side effects, such as thrombocytopenia.
Zhicheng Wang, Feng Cai, Xiaoyu Chen, Meihong Luo, Lingling Hu, Yuan Lu   +5 more
doaj   +1 more source

Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans : lost in translation [PDF]

, 2013
We greatly appreciate the comments offered by Drs Rolle, Takematsu, and Hoffman and the opportunity to put our work into a wider perspective. We share the view that our work does not reflect the clinical situation but rather provides a proof of mechanism
Boehrer, Brunt, Dafters, Docherty, Grunau, Henry, Hysek, Hysek, Hysek, Hysek, Hysek, Liechti, Liechti, Martin, Mills, Mithoefer, Morefield, Oehen, Parrott, Ramoska, Rietjens, Rogers, Rusyniak, Schutte, Sprague, Sprague, Williams   +26 more
core   +1 more source

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

Advanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid, Aishik Chakraborty, Wei Luo, Juhi Bora, John Joseph Kelly, John Andrew Ronald, Arghya Paul   +6 more
wiley   +1 more source

Application of magnetically induced hyperthermia on the model protozoan Crithidia fasciculata as a potential therapy against parasitic infections

, 2012
Magnetic hyperthermia is currently an EU-approved clinical therapy against tumor cells that uses magnetic nanoparticles under a time varying magnetic field (TVMF).
Asín, L., Goya, G. F., Grazú, V., Ibarra, M. R., Marquina, C., Moros, M., Silber, A. M., Torres, T. E.   +7 more
core   +1 more source

Hybrid Microdiscs for Magnetically Induced Non‐Cytotoxic Thermal Actuation and Programmable Biomolecule Delivery

Advanced Functional Materials, EarlyView.
Hybrid magnetic microdiscs with customizable size and composition are engineered through refined photolithography and LbL assembly. Embedded Fe3O4 nanoparticles enable localized, non‐cytotoxic heating, while protein cargos can be incorporated in tunable quantities.
Daniela Iglesias‐Rojas, Danny Villanueva, Jon Mentxaka‐Salgado, Nerea Lete, Ane Olazagoitia‐Garmendia, Eduardo Fernández, Iñaki Orue, Alfredo García‐Arribas, Maria Luisa Fdez‐Gubieda, Ainara Castellanos‐Rubio, Robert Morel, Bernard Dieny, Maite Insausti, Idoia Castellanos‐Rubio   +13 more
wiley   +1 more source

Acute postoperative sepsis mimicking symptomology suspicious for malignant hyperthermia: case report [PDF]

Revista Brasileira de Anestesiologia, 2020
Background: Sepsis is a life-threatening organ dysfunction with non-specific clinical features that can mimic other clinical conditions with hyper metabolic state such as malignant hyperthermia.
Vendhan Ramanujam, Christopher R. Hoffman, Kevin Russo, Michael S. Green   +3 more
doaj   +3 more sources