Results 51 to 60 of about 32,848 (294)

Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer [PDF]

, 2019
Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics ...
Ceelen, Wim, De Clercq, Kaat, De Wever, Olivier, Descamps, Benedicte, Hoorens, Anne, Vermeulen, An, Vervaet, Chris, Xie, Feifan   +7 more
core   +2 more sources

Current Trends in Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Peritoneal Disease from Appendiceal and Colorectal Malignancies

Journal of Clinical Medicine, 2022
Peritoneal carcinomatosis (PC) is a poor prognostic factor for all malignancies. This extent of metastatic disease progression remains difficult to treat with systemic therapies due to poor peritoneal vascularization resulting in limited drug delivery ...
Megan M Harper, Joseph J Kim, P. Pandalai   +2 more
semanticscholar   +1 more source

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source

Complications and Mortality Rate of Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy: Italian Peritoneal Surface Malignancies Oncoteam Results Analysis

Cancers, 2022
Simple Summary Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy has been introduced in order to improve outcomes for selected patients with peritoneal surface malignancies.
F. Carboni, M. Valle, M. Vaira, P. Sammartino, O. Federici, M. Robella, M. Deraco, M. Framarini, A. Macrì, C. Sassaroli, P. Lippolis, A. di Giorgio, D. Biacchi, Lorena Martín-Román, I. Sperduti, D. Baratti   +15 more
semanticscholar   +1 more source

Peritoneal carcinomatosis [PDF]

, 2013
Several gastrointestinal and gynecological malignancies have the potential to disseminate and grow in the peritoneal cavity. The occurrence of peritoneal carcinomatosis (PC) has been shown to significantly decrease overall survival in patients with liver
Ansaloni L, BAIOCCHI, Gian Luca, Catena F., Coccolini F, Ghermandi C, GHEZA, Federico, GIULINI, Stefano Maria, Iusco D, Lotti M, Melotti R, Virzì S   +10 more
core   +1 more source

Survival prediction by Bayesian network modeling for pseudomyxoma peritonei after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy

Cancer Medicine, 2022
To establish a survival prognostic model for pseudomyxoma peritonei (PMP) treated with cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) based on Bayesian network (BN).
Xin Zhao, Xin-Bao Li, Yulin Lin, R. Ma, Ying Zhang, Dazhao Xu, Yan Li   +6 more
semanticscholar   +1 more source

Intraperitoneal chemotherapy for gastric cancer with peritoneal carcinomatosis: is HIPEC the only answer? [PDF]

, 2014
Gastric cancer with peritoneal carcinomatosis is notorious for its dismal prognosis. While the pathophysiology of peritoneal dissemination is still controversial, the rapid downhill course is universal.
Kwong, DLW, Lam, KO, Law, BTT, Law, SYK
core   +1 more source

Peritoneal carcinosis of ovarian origin [PDF]

, 2010
Epithelial ovarian cancer (EOC) is the second most common genital malignancy in women and is the most lethal gynecological malignancy, with an estimated five-year survival rate of 39%.
Fagotti, A, Fanfani, F, Gallotta, V, Naldini, A, ROMANO, Federico, Rossitto, C, Scambia, G., Vigliotta, M   +7 more
core   +2 more sources

Albumin-based cancer therapeutics for intraperitoneal drug delivery : a review [PDF]

, 2020
Albumin is a remarkable carrier protein with multiple cellular receptor and ligand binding sites, which are able to bind and transport numerous endogenous and exogenous compounds.
Al Rawahi T, Carlier C, Daugirdas JT, Dedrick RL, Fan R, Flessner MF, Goodman MD, Hartung G, Kragh-Hansen U., Lotze MT, Maltas E, Oseledchyk A, Sjobring U, Sun C, Zhao D   +14 more
core   +2 more sources

Perioperative anaesthetic management in cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC): a retrospective analysis in a single tertiary care cancer centre

Pleura and Peritoneum, 2022
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with increased morbidity and mortality. We retrospectively analysed the perioperative anesthetic management in patients undergoing HIPEC surgery.
Gupta Raghav, Gupta Nishkarsh, Sirohiya Prashant, Pandit Anuja, Ratre Brajesh Kumar, Vig Saurabh, Bhan Swati, Singh Ram, Kumar Balbir, Bhopale Shweta, Mishra Seema, Garg Rakesh, Bharati Sachidanand Jee, Kumar Vinod, Deo Suryanarayana, Bhatnagar Sushma   +15 more
doaj   +1 more source