Results 1 to 10 of about 125,918 (262)
Frontiers in Pharmacology, 2018 Hypertrophic scars formed after burns remain a challenge in clinical practice. Development of effective scar therapies relies on validated animal models that mimic human hypertrophic scars. A consistent porcine full-thickness burn hypertrophic scar model
Xingwang Deng +12 more
exaly +4 more sources
Update on Hypertrophic Scar Treatment
Clinics, 2014 Scar formation is a consequence of the wound healing process that occurs when body tissues are damaged by a physical injury. Hypertrophic scars and keloids are pathological scars resulting from abnormal responses to trauma and can be itchy and painful, causing serious functional and cosmetic disability.
Jayme Adriano Farina Junior
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Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2021 Introduction: Keloid and hypertrophic scar are pathological scars resulting from excessive accumulation of collagen in wound healing process. Data about profiles of keloid and hypertrophic scar are rarely found in Indonesia. Therefore, it is necessary to
Fania Ayu Wardani +2 more
doaj +2 more sources
Distinct diversity of skin cell populations of rhinophyma and hypertrophic scar illustrated by scRNA-seq [PDF]
Frontiers in ImmunologyIntroductionThe clinical manifestations and presentation of rhinophyma closely resemble those of hypertrophic scar tissue, both presenting as firm, fibrotic growths. Despite this phenotypic similarity, a critical divergence is observed following surgical
Qiannan Li +9 more
doaj +2 more sources
The Korean Journal of Gastroenterology, 2022 Background/Aims: Anastomotic stricture at the esophagus and the conduit anastomosis site after the surgical resection of esophageal cancer is relatively common.
Yong Won Seong +6 more
doaj +2 more sources
Effects of Botulinum Toxin Type A on Collagen Deposition in Hypertrophic Scars
Molecules, 2012 A recent study reported that Botulinum toxin type A (BTXA) could inhibit the growth of hypertrophic scars and improve their appearance. However, the mechanism of BTXA’s action on hypertrophic scars is still unknown.
Zhibo Xiao
exaly +3 more sources
Causal correlation between inflammatory cytokines and hypertrophic scar based on two-sample Mendelian randomization [PDF]
Journal of Genetic Engineering and BiotechnologyHypertrophic scars result from the abnormal proliferation of fibroblasts and the accumulation of collagen after skin injury. In this process, inflammatory cytokines act as crucial regulators. The large − scale release of inflammatory cytokines aberrantly
Lujia Mao +5 more
doaj +2 more sources
Effects of Apremilast on Induced Hypertrophic Scar of Rabbits [PDF]
Archives of Razi Institute, 2021 The present study aimed to assess the effect of Apremilast on experimentally induced hypertrophic scars in rabbits. A total of 40 healthy male New Zealand White rabbits between 6 and 12 months of age were assigned to four groups (n=10).
D Nidhal Ghazy, A Rahmah Abu- Raghif
doaj +1 more source
Differences in Hypertrophic Scar Fibroblasts according to Scar Severity: Expression of Transforming Growth Factor beta1 at the mRNA and Protein Levels [PDF]
Archives of Aesthetic Plastic Surgery, 2015 Background Hypertrophic scars result from excessive collagen deposition and increased transforming growth factor beta-1 (TGF-beta1) levels. We hypothesized that the expression of TGF-beta1 mRNA and protein would increase with the clinical severity of ...
Se Young Kim +3 more
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Medicina, 2023 Background and Objectives: The prevalence of hypertrophic scarring after a burn is approximately 70%. Despite advances in burn management, there is currently no gold standard treatment to reduce or prevent its occurrence.
Alejandro Joglar +5 more
doaj +1 more source