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Exploring the mechanism underlying hyperuricemia using comprehensive research on multi-omics
Scientific Reports, 2023 Hyperuricemia involves multiple complex metabolisms, but no study has conducted a comprehensive analysis using human blood and urine metabolomics for hyperuricemia. Serum and urine samples from 10 patients with hyperuricemia and 5 controls were collected
Hengrui Liu +5 more
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HYPERURICEMIA IN MYXEDEMA* [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1960 ABSTRACT Serum uric acid levels were determined in 28 myxedematous patients and compared to the levels in 7 hyperthyroid patients and 33 normal subjects. Urinary urate excretions were also measured in 18 patients and 24-hour uric acid excretion rates determined in 16.
Robert D. Leeper +3 more
openalex +4 more sources
Journal of Translational Medicine, 2023 Background The prevalence of hyperuricemia, gout, and heart failure (HF) is on the rise, and these conditions often share similar risk factors. The present study aimed to evaluate the relationship among hyperuricemia, gout, HF, and all-cause mortality ...
Yingdong Han +7 more
doaj +2 more sources
Frontiers in Endocrinology, 2022 Background and aimsMetabolic dysfunction-associated fatty liver disease (MAFLD) is a newly emerged term that is suggested to better reflect the pathogenesis of nonalcoholic fatty liver disease (NAFLD); however, the association between hyperuricemia and ...
Chengzhang Yang +27 more
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Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016–2019 [PDF]
The Korean Journal of Internal MedicineBackground/Aims Hyperuricemia plays an essential role in the gout. Despite the clinical significance of hyperuricemia, a direct relationship between oral health and hyperuricemia has not been established.
Junyong Park +4 more
doaj +2 more sources
Prevalence of and trends in hyperuricemia by race and ethnicity among US adolescents, 1999–2018 [PDF]
Arthritis Research & TherapyPurpose Our objective was to ascertain the most recent prevalence and trends of hyperuricemia among adolescents, stratified by sex and race/ethnicity subgroups, as well as to investigate potential risk factors associated with hyperuricemia in US ...
Kaifeng Guo +7 more
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Hyperuricemia and Associated Factors in Adult Cardiac Patients in Western Oromia, Ethiopia [PDF]
Nutrition and Metabolic InsightsBackground: Individuals who have hyperuricemia are at increased risk of cardiovascular diseases due to factors such as endothelial dysfunction, insulin resistance, and increased production of oxygen-free radicals.
Bedasa Addisu +5 more
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Frontiers in Genetics, 2021 Circular RNAs (circRNAs) are non-coding RNAs (ncRNAs) with a single-stranded covalently closed-loop structure, and their abnormal expression may participate in the pathogenesis of various human diseases.
Fei Dai +11 more
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Frontiers in Pharmacology, 2021 Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders.
Quan-Bo Zhang +18 more
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Interrelationships between hyperuricemia, metabolic syndrome and chronic kidney disease in patients with diabetes mellitus [PDF]
Archives of the Balkan Medical Union, 2020 Introduction. Hyperuricemia is a strong predictor of an altered metabolic status. There are complex interrelationships between hyperuricemia, type 2 diabetes mellitus (T2DM), metabolic syndrome (MS) and chronic kidney disease (CKD).
Adriana BAIDOG +7 more
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