Results 1 to 10 of about 47,286 (245)

Expression Profile and Potential Function of Circular RNAs in Peripheral Blood Mononuclear Cells in Male Patients With Primary Gout

open access: yesFrontiers in Genetics, 2021
Circular RNAs (circRNAs) are non-coding RNAs (ncRNAs) with a single-stranded covalently closed-loop structure, and their abnormal expression may participate in the pathogenesis of various human diseases.
Fei Dai   +11 more
doaj   +1 more source

Interrelationships between hyperuricemia, metabolic syndrome and chronic kidney disease in patients with diabetes mellitus [PDF]

open access: yesArchives of the Balkan Medical Union, 2020
Introduction. Hyperuricemia is a strong predictor of an altered metabolic status. There are complex interrelationships between hyperuricemia, type 2 diabetes mellitus (T2DM), metabolic syndrome (MS) and chronic kidney disease (CKD).
Adriana BAIDOG   +7 more
doaj   +1 more source

MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome

open access: yesFrontiers in Pharmacology, 2021
Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders.
Quan-Bo Zhang   +18 more
doaj   +1 more source

The treatment of hyperuricemia [PDF]

open access: yesInternational Journal of Cardiology, 2016
Hyperuricemia has long been established as the major etiologic factor in gout. Alongside with an inflammatory state triggered by urate crystal deposition in the joints, hyperuricemia displayed additional pathophysiological consequences leading to tissue inflammation mainly in the vascular wall.
Gliozzi, Micaela   +3 more
openaire   +4 more sources

Research Progress in the Regulation of Gut Microbiota on Diet-Induced Hyperuricemia

open access: yesShipin gongye ke-ji, 2022
Hyperuricemia is a metabolic disease with excessively high level of uric acid in blood. It is triggered by the disorder of purine metabolism and/or uric acid excretion in human, and the purine-rich and fructose-rich diets and purine was confirmed to ...
Yingping MENG   +3 more
doaj   +1 more source

Exploring the mechanism underlying hyperuricemia using comprehensive research on multi-omics

open access: yesScientific Reports, 2023
Hyperuricemia involves multiple complex metabolisms, but no study has conducted a comprehensive analysis using human blood and urine metabolomics for hyperuricemia. Serum and urine samples from 10 patients with hyperuricemia and 5 controls were collected
Hengrui Liu   +5 more
doaj   +1 more source

Association and Interaction between Heavy Metals and Hyperuricemia in a Taiwanese Population

open access: yesDiagnostics, 2023
The prevalence of hyperuricemia in Taiwan is high, and hyperuricemia has been associated with a risk of developing several diseases. Although the traditional risk factors for hyperuricemia are well known, the relationship between heavy metals and ...
Lu-Heng Lu   +7 more
doaj   +1 more source

Joint association of hyperuricemia and chronic kidney disease with mortality in patients with chronic heart failure

open access: yesFrontiers in Endocrinology, 2023
BackgroundThe joint association of hyperuricemia and chronic kidney disease (CKD) with mortality in patients with chronic heart failure (CHF) is not conclusive.MethodsThis retrospective cohort study was conducted in Chinese People's Liberation Army ...
Chi Wang   +14 more
doaj   +1 more source

Pilot study: asymptomatic hyperuricemia patients with obesity and nonalcoholic fatty liver disease have increased risk of double contour sign [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2020
Background/Aims Double contour sign (DCS) is a representative ultrasonographic finding in gout. DCS is evidence of monosodium urate deposit in gouty arthritis and has been identified in some patients with asymptomatic hyperuricemia. However, the specific
Hong Ki Min   +2 more
doaj   +1 more source

Increased Overall Heart Rate Irregularity Risk by Hyperuricemia in the General Population: Results from the Korean National Health and Nutrition Examination Survey

open access: yesMedicina, 2020
Background and objectives: Hyperuricemia is one of the well-known cardiovascular risk factors. There is a growing interest in the association between hyperuricemia and arrhythmia.
Yeonghee Eun   +9 more
doaj   +1 more source

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