Results 1 to 10 of about 31,399 (259)
ABSTRACT Serum uric acid levels were determined in 28 myxedematous patients and compared to the levels in 7 hyperthyroid patients and 33 normal subjects. Urinary urate excretions were also measured in 18 patients and 24-hour uric acid excretion rates determined in 16.
Robert D. Leeper+3 more
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The treatment of hyperuricemia [PDF]
Hyperuricemia has long been established as the major etiologic factor in gout. Alongside with an inflammatory state triggered by urate crystal deposition in the joints, hyperuricemia displayed additional pathophysiological consequences leading to tissue inflammation mainly in the vascular wall.
Gliozzi, Micaela+3 more
openaire +4 more sources
Hyperuricemia induces endothelial dysfunction
Takahiko Nakagawa+2 more
exaly +2 more sources
Hyperuricemia and risk of stroke: A systematic review and meta‐analysis [PDF]
James P Guevara, Hyon K Choi
exaly +2 more sources
Hyperuricemia and hypertension
Rapicka Dorota, Fabian-Danielewska Anna. Hyperuricemia and hypertension. Journal of Education, Health and Sport. 2019;9(7):233-239. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3269865 http://ojs.ukw.edu.pl/index.php/johs/article/view/7124 https://pbn.nauka.gov.pl/sedno-webapp/works/917534 The journal has had 7 points in ...
Dorota Rapicka, Anna Fabian-Danielewska
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Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc+12 more
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Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio+9 more
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Antiepileptic drugs reduce serum uric acid [PDF]
Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab+7 more
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The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
George, Jacob, Struthers, Allan
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Gouty arthritis of the spine in a renal transplant patient : a clinical case report: an unusual presentation of a common disease [PDF]
Axial gout is a well-documented but uncommon manifestation of gout. Its mimicking nature and the impracticality of axial joint aspiration might considerably delay its diagnosis.
Dhaese, Sofie+4 more
core +1 more source