Results 161 to 170 of about 228,932 (402)

Integration of Clinical Criteria into the Training of Deep Models: Application to Glucose Prediction for Diabetic People [PDF]

arXiv, 2020
Standard objective functions used during the training of neural-network-based predictive models do not consider clinical criteria, leading to models that are not necessarily clinically acceptable. In this study, we look at this problem from the perspective of the forecasting of future glucose values for diabetic people.
arxiv  

A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]

, 2011
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi, David Dawson, Donald Rao, Francesco DeMayo, John Nemunaitis, Kelly Stehling, Marie-Claude Gingras, Michael Norman, Nancy Templeton, Neil Senzer, Richard Gibbs, Shi-He Liu, William Fisher, Zhaohui Wang   +13 more
core   +1 more source

Hypoglycemia in the hospital

Journal of Community Hospital Internal Medicine Perspectives, 2011
Hypoglycemia is a common adverse event affecting hospitalized patients with diabetes. This paper reviews the data regarding optimization of glucose in hospitalized patients, discusses the scope and significance of hypoglycemia in the hospital, and makes recommendations on how to reduce the risk of this serious adverse event.
openaire   +5 more sources

Development and Validation of a Tool to Identify Patients With Type 2 Diabetes at High Risk of Hypoglycemia-Related Emergency Department or Hospital Use

JAMA Internal Medicine, 2017
Importance Hypoglycemia-related emergency department (ED) or hospital use among patients with type 2 diabetes (T2D) is clinically significant and possibly preventable.
A. Karter, E. M. Warton, K. Lipska, J. Ralston, H. Moffet, Geoffrey G. Jackson, E. Huang, Donald R. Miller   +7 more
semanticscholar   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao, Marie Mostue Naume, Brenda C. M. de Winter, Thomas Krag, Sissel Sundell Haslund‐Krog, Karoline Lolk Revsbech, John Vissing, Helle Holst, Morten Hylander Møller, Tessa Munkeboe Hornsyld, Morten Dunø, Christina Engel Hoei‐Hansen, Alfred Peter Born, Per Bo Jensen, Mette Cathrine Ørngreen   +14 more
wiley   +1 more source

Hypoglycemia Event Rates: A Comparison Between Real-World Data and Randomized Controlled Trial Populations in Insulin-Treated Diabetes

Diabetes Therapy, 2016
IntroductionHypoglycemia is the most common adverse effect of diabetes therapy, particularly insulin treatment. Hypoglycemia is associated with considerable clinical and economic burden, and may be under-reported.
L. Elliott, C. Fidler, A. Ditchfield, Trine Stissing   +3 more
semanticscholar   +1 more source

Best fit framework synthesis of qualitative studies on factors associated with medication nonadherence in people with type 2 diabetes using the COM‐B model

British Journal of Clinical Pharmacology, EarlyView.
This review aimed to synthesize factors associated with medication nonadherence among people with type 2 diabetes (PwT2D), using the Capability, Opportunity, Motivation and Behaviour (COM‐B) model as the a priori model. Studies published between January 2014 and April 2024 were searched on five databases.
Vivien Teo, John Weinman, Kai Zhen Yap
wiley   +1 more source

Glycemic Variability Before And After Hypoglycemia Across Different Timeframes In Type 1 Diabetes With And Without Automated Insulin Delivery [PDF]

arXiv
Managing Type 1 diabetes (T1D) aims to optimize glucose levels within the target range while minimizing hyperglycemia and hypoglycemia. Exercise presents additional challenges due to complex effects on glucose dynamics. Despite advancements in diabetes technology, significant gaps remain in understanding the relationship between exercise, glycemic ...
arxiv  

Monitoring of diabetic dogs [PDF]

, 2012
Diabetes mellitus is one of the most common endocrine disorders in the dog. Although diagnostics are relatively straightforward, treatment and especially adequate long-term monitoring are challenging.
Daminet, Sylvie, Smets, Pascale, Van de Maele, Isabel, Vandenabeele, Sophie, Willems, Annelies   +4 more
core  

TOLBUTAMIDE HYPOGLYCEMIA IN ACUTELY DEPANCREATIZED DOGS*† [PDF]

, 1959
Martin Kurtz, Charles M. Holtzman, Edward Meilman   +2 more
openalex   +1 more source