The association between adult-type hypolactasia and symptoms of functional dyspepsia [PDF]
Genetics and Molecular Biology, 2018 Functional dyspepsia and lactose intolerance (adult-type hypolactasia, ATH) are common conditions that may coexist or even be confounded. Their clinical presentation can be similar, however, lactose intolerance does not form part of the diagnostic ...
André Castagna Wortmann +12 more
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The incidence of adult type hypolactasia in patients with irritable bowel syndrome [PDF]
Gastroenterology Review, 2023 The incidence of lactose intolerance in irritable bowel syndrome (IBS) varies in the literature (27-72%). Primary adult lactase deficiency (adult type hypolactasia) is the most common type of primary enzyme deficiency. Complaints related to lactose intolerance may overlap with the symptoms of IBS.To assess the prevalence of primary hypolactasia in ...
Danuta Domżał-Magrowska +2 more
doaj +6 more sources
Frequency of LCT -13910C>T single nucleotide polymorphism associated with adult-type hypolactasia/lactase persistence among Brazilians of different ethnic groups [PDF]
Nutrition Journal, 2009 Background Adult-type hypolactasia, the physiological decline of lactase some time after weaning, was previously associated with the LCT -13910C>T polymorphism worldwide except in Africa.
Silva Joyce MK +5 more
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Comparison of Quick Lactose Intolerance Test in duodenal biopsies of dyspeptic patients with single nucleotide polymorphism LCT-13910C>T associated with primary hypolactasia/lactase-persistence [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar +3 more
doaj +3 more sources
Improvement in Lactose Tolerance in Hypolactasic Subjects Consuming Ice Creams with High or Low Concentrations of Bifidobacterium bifidum 900791 [PDF]
Foods, 2021 Although Bifidobacterium bifidum expresses lactase activity, no clinical trials have determined its impact on lactose-intolerant subjects. This study evaluated whether acute and chronic ingestion of ice creams containing B.
Gabriela Aguilera +3 more
doaj +2 more sources
LCT-22018G>A single nucleotide polymorphism is a better predictor of adult-type hypolactasia/lactase persistence in Japanese-Brazilians than LCT-13910C>T [PDF]
Clinics, 2010 Rejane Mattar +3 more
doaj +7 more sources
Diagnosis of adult-type hypolactasia/lactase persistence: genotyping of single nucleotide polymorphism (SNP C/T-13910) is not consistent with breath test in Colombian Caribbean population [PDF]
Arquivos de Gastroenterologia, 2012 CONTEXT: Genotyping of single nucleotide polymorphism (SNP C/T-13910) located upstream of the lactase gene is used to determine adult-type hypolactasia/lactase persistence in North-European Caucasian subjects.
Evelyn Mendoza Torres +3 more
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Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia [PDF]
Brazilian Journal of Medical and Biological Research, 2007 The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910.
A.C. Bulhões +5 more
doaj +2 more sources
Genetic aspects of lactase deficiency in indigenous populations of Siberia [PDF]
Вавиловский журнал генетики и селекцииThe ability to metabolize lactose in adulthood is associated with the persistence of lactase enzyme activity. In European populations, lactase persistence is determined mainly by the presence of the rs4988235-T variant in the MCM6 gene, which increases ...
B. A. Malyarchuk
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ORAL ADMINISTRATION OF EXOGENOUS LACTASE IN TABLETS FOR PATIENTS DIAGNOSED WITH LACTOSE INTOLERANCE DUE TO PRIMARY HYPOLACTASIA [PDF]
Arquivos de Gastroenterologia, 2016 Background Primary hypolactasia is a common condition where a reduced lactase activity in the intestinal mucosa is present. The presence of abdominal symptoms due to poor absorption of lactose, which are present in some cases, is a characteristic of ...
Carlos Fernando de Magalhães FRANCESCONI +7 more
doaj +2 more sources