Morphological method for the diagnosis of human adult type hypolactasia. [PDF]
Gut, 1994 The primary adult type hypolactasia is the most common form of genetically determined disaccharidase deficiency. This study examined a large and homogeneous population of the south of Italy: surgical biopsy specimens of proximal jejunum from 178 adult subjects have been assayed for disaccharidase activities; the expression of lactase protein and ...
Luigi Maiuri +7 more
openalex +6 more sources
Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population
Annals of Human Biology, 2022 Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase
Stefan Németh +5 more
doaj +1 more source
The role of a combined probiotic in the treatment of lactase deficiency
Терапевтический архив, 2021 Aim. To study the effectiveness of the combined probiotic Bifiform and the enzyme lactase in the treatment of secondary lactase deficiency (SLD). Materials and methods.
Irina N. Ruchkina, Nina A. Fadeeva
doaj +1 more source
Polymorphism of the genetic determinants of bone mineral metabolism in various groups of the Komi people [PDF]
Вестник археологии, антропологии и этнографии, 2021 The subject of the study is autochthonous population of the Northern and Middle Cis-Urals: Komi-Permyaks, Komi (Zyryans), and Komi-Izhems. The aim of the study is to compare the population frequencies of the LCT (rs4988235) and VDR (FokI rs2228570 and ...
Kozlov A.I.
doaj +1 more source
A worldwide correlation of lactase persistence phenotype and genotypes [PDF]
, 2010 Background: The ability of adult humans to digest the milk sugar lactose - lactase persistence - is a dominant Mendelian trait that has been a subject of extensive genetic, medical and evolutionary research.
Ingram, C.J.E. +4 more
core +3 more sources
Lactose intolerance: Causes, effects, diagnosis and symptom control [PDF]
, 2013 Lactose intolerance is a very common complaint which leads to a number of distressing gut symptoms in those affected. It can be quite easy to control by reducing milk consumption, and possibly by adding lactase to the diet. However, clinicians should be
Coutts, A. M.
core +1 more source
The FASEB Journal, Volume 34, Issue 3, Page 3983-3995, March 2020., 2020 Abstract Background and aims: Intestinal adaptation in short bowel syndrome (SBS) includes morphologic processes and functional mechanisms. This study investigated whether digestive enzyme expression in the duodenum and colon is upregulated in SBS patients. Method: Sucrase‐isomaltase (SI), lactase‐phlorizin hydrolase (LPH), and neutral Aminopeptidase N
Jan de Laffolie +13 more
wiley +1 more source
Laktózintolerancia: a laktázgén C/T-13910 polimorfizmusának és a hidrogénkilégzési teszt pontosságának retrospektív kiértékelése gasztroenterológiai szakrendelésen [PDF]
, 2016 Absztrakt Bevezetés: A felnőtt típusú hypolactasia a leggyakoribb szénhidrát-felszívódási zavar. Célkitűzés: A laktázgén C/T-13910-polimorfizmus eloszlásának és a H2-kilégzési teszt
Buzás, György +2 more
core +1 more source
Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment [PDF]
, 2010 Clinical manifestations of lactase (LCT) deficiency include intestinal and extra-intestinal symptoms. Lactose hydrogen breath test (H2-BT) is considered the gold standard to evaluate LCT deficiency (LD).
A. v. Eckardstein +13 more
core +3 more sources
Hypolactasia is associated with insulin resistance in nonalcoholic steatohepatitis. [PDF]
World J Hepatol, 2016 To assess lactase gene (LCT)-13910C>T polymorphisms in Brazilian non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) patients in comparison with healthy controls.This was a transverse observational clinical study with NAFLD patients who were followed at the Hepatology Outpatient Unit of the Hospital das Clínicas, São Paulo,
de Campos Mazo DF +10 more
europepmc +4 more sources