Results 31 to 40 of about 713 (175)

Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population

open access: yesAnnals of Human Biology, 2022
Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase
Stefan Németh   +5 more
doaj   +1 more source

Analytical Validation of a New Enzymatic and Automatable Method for d-Xylose Measurement in Human Urine Samples. [PDF]

open access: yesBiomed Res Int, 2017
Hypolactasia, or intestinal lactase deficiency, affects more than half of the world population. Currently, xylose quantification in urine after gaxilose oral administration for the noninvasive diagnosis of hypolactasia is performed with the hand‐operated nonautomatable phloroglucinol reaction.
Sánchez-Moreno I   +11 more
europepmc   +2 more sources

The role of a combined probiotic in the treatment of lactase deficiency

open access: yesТерапевтический архив, 2021
Aim. To study the effectiveness of the combined probiotic Bifiform and the enzyme lactase in the treatment of secondary lactase deficiency (SLD). Materials and methods.
Irina N. Ruchkina, Nina A. Fadeeva
doaj   +1 more source

Polymorphism of the genetic determinants of bone mineral metabolism in various groups of the Komi people [PDF]

open access: yesВестник археологии, антропологии и этнографии, 2021
The subject of the study is autochthonous population of the Northern and Middle Cis-Urals: Komi-Permyaks, Komi (Zyryans), and Komi-Izhems. The aim of the study is to compare the population frequencies of the LCT (rs4988235) and VDR (FokI rs2228570 and ...
Kozlov A.I.
doaj   +1 more source

Digestive enzyme expression in the large intestine of children with short bowel syndrome in a late stage of adaptation

open access: yesThe FASEB Journal, Volume 34, Issue 3, Page 3983-3995, March 2020., 2020
Abstract Background and aims: Intestinal adaptation in short bowel syndrome (SBS) includes morphologic processes and functional mechanisms. This study investigated whether digestive enzyme expression in the duodenum and colon is upregulated in SBS patients. Method: Sucrase‐isomaltase (SI), lactase‐phlorizin hydrolase (LPH), and neutral Aminopeptidase N
Jan de Laffolie   +13 more
wiley   +1 more source

Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population. [PDF]

open access: yesPLoS ONE, 2012
Adult-type hypolactasia is a common phenotype caused by the lactase enzyme deficiency. The -13910 C>T polymorphism, located 14 Kb upstream of the lactase gene (LCT) in the MCM6 gene was associated with lactase persistence (LP) in Europeans.
Deise C Friedrich   +3 more
doaj   +1 more source

A felnőttkori hypolactasia születésikohorsz-vizsgálata [PDF]

open access: yesOrvosi Hetilap, 2019
Abstract: Introduction and aim: To assess the prevalence of lactase gene promoter C/T13910 phenotypes in patients with lactose intolerance symptoms and to analyze the birth-cohort phenomenon in lactose-intolerant patients. Method: 1266 patients consulted between 2010 and 2017 were enrolled.
openaire   +1 more source

PROSPECTS OF SYNTHETIC POLYMERS APPLICATION AS INERT CARRIERS FOR β-GALACTOSIDASE IMMOBILISATION

open access: yesНаука. Инновации. Технологии, 2022
The actuality of lactose-reduced and delactosed products manufacturing is founded. Methods of β-galactosidase immobilization and it’s peculiarities, concerned with type of carrier, are considered.
Victoria Evgen'evna Suprunchuk   +2 more
doaj  

Polymorphism of the LCT gene regulatory region in Turkicspeaking populations of the Altay-Sayan region (southern Siberia)

open access: yesВавиловский журнал генетики и селекции, 2017
Retention of lactase activity in adulthood (lactase persistence) is one of the most important adaptive traits for human populations that consume fresh milk from domestic animals.
I. V. Pilipenko   +4 more
doaj   +1 more source

GutSelf: Interindividual Variability in the Processing of Dietary Compounds by the Human Gastrointestinal Tract

open access: yesMolecular Nutrition &Food Research, Volume 63, Issue 21, November 2019., 2019
Despite numerous examples of interindividual variability in the processing of food by the human gastrointestinal tract, the knowledge on this topic, as illustrated for polymorphisms in mineral absorption, remains fragmented. The GutSelf review sets the base for motivating future research specifically addressing the issue of the interindividual ...
Barbara Walther   +14 more
wiley   +1 more source

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