Results 81 to 90 of about 96,734 (308)

The biological impact of living with chronic breathlessness – A role for the hypothalamic–pituitary–adrenal axis?

, 2014
Breathlessness is a common and distressing symptom in advanced cardiorespiratory disease, with recognised psychological, functional and social consequences. The biological impact of living with chronic breathlessness has not been explored.
Fallon, M., Spathis, A., Clow, A., Ryan, R., Booth, S.   +4 more
core   +1 more source

Elimination Profile of Deflazacort and Metabolites in Urine and Plasma Following Oral Administration: Relevance to Sports Drug Testing

Drug Testing and Analysis, EarlyView.
Results confirm that the MRL of 30 ng/mL for 21‐desacetyl‐deflazacort together with a 3‐day washout period is an appropriated strategy to detect oral deflazacort administration in sport competition. ABSTRACT Deflazacort (DEF) is a glucocorticoid prohibited in sports competitions when orally administered.
Sergi Coll, Claudia Bressan, Núria Monfort, Ana Aldea‐Perona, Marcel·lí Carbó, Rosa Ventura   +5 more
wiley   +1 more source

Hypothalamic-pituitary-adrenal axis response in borderline personality disorder without post-traumatic features

, 2018
Hypothalamic–pituitary–adrenal (HPA) axis sensitivity was investigated in 32 non-medicated patients with borderline personality disorder without comorbid post-traumatic syndromes and in 18 normal individuals using a modified dexamethasone suppression ...
López-Ibor Alcocer, María Inés, Brotons, Loreto, Molina, Rosa, López-Ibor Aliño, Juan José, Carrasco Perera, José Luis, Pastrana, Jose I., Díaz Marsa, Marina Francisca   +6 more
core   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang, Esben Strodl, Leanne Barron, Matthew Bambling, Luis Vitetta   +4 more
wiley   +1 more source

Amygdala volume and hypothalamic-pituitary-adrenal axis reactivity to social stress [PDF]

, 2017
The amygdala plays a central role in emotional processing and has an activating influence on the hypothalamic-pituitary-adrenal (HPA) axis. Structural changes in the amygdala have been associated with early adversity and, in principle, may contribute to ...
Murray, L, Sarah L. Halligan, Christina Moutsiana, Tom J. Barry, Moutsiana, C., Pasco Fearon, Barry, Tom J., Fearon, Pasco, Johnstone, Tom, Barry, TJ, Johnstone, T, Tom Johnstone, Halligan, S.L., Fearon, P, Halligan, SL, Murray, Lynne, Moutsiana, Christina, Halligan, Sarah L., Moutsiana, C, Barry, T.J., Fearon, P., Johnstone, T., Murray, L., Lynne Murray, Halligan, Sarah   +24 more
core   +1 more source

Machine learning‐based prediction of elevated N terminal pro brain natriuretic peptide among US general population

ESC Heart Failure, Volume 12, Issue 2, Page 859-868, April 2025.
Abstract Aims Natriuretic peptide‐based pre‐heart failure screening has been proposed in recent guidelines. However, an effective strategy to identify screening targets from the general population, more than half of which are at risk for heart failure or pre‐heart failure, has not been well established.
Yuichiro Mori, Shingo Fukuma, Kyohei Yamaji, Atsushi Mizuno, Naoki Kondo, Kosuke Inoue   +5 more
wiley   +1 more source

Effectiveness of Artemisia pallens against behavioral depression and impact on monoaminergic and GABAergic systems

Bangladesh Journal of Pharmacology
Depression is characterized by decreased monoamine levels (dopamine, noradrenaline, serotonin), gamma-aminobutyric acid (GABA), elevated corticosterone, and dysregulation of the hypothalamic-pituitary-adrenal axis. This study aims to examine the effects
Deorao Madhaorao Awari, Rajendra O. Ganjiwale   +1 more
doaj   +1 more source

New directions for the treatment of adrenal insufficiency.

Frontiers in Endocrinology, 2015
Adrenal disease, whether primary, caused by defects in the hypothalamic-pituitary-adrenal (HPA) axis, or secondary, caused by defects outside the HPA axis, usually results in adrenal insufficiency, which requires lifelong daily replacement of ...
Gerard eRuiz-Babot, Irene eHadjidemetriou, Peter James King, Leonardo eGuasti   +3 more
doaj   +1 more source

Political Social Identity Threat Predicts Increases in Affective Polarisation Over Time, but Not Changes in Well‐Being

European Journal of Social Psychology, EarlyView.
ABSTRACT Affective polarisation, a growing hostility toward political outgroups, is a phenomenon rooted in social identity. Social identity threat—the expectation of experiencing some form of denigration based on a self‐relevant group identity—is thought to be a major driver of affective polarisation.
Brandon McMurtrie, Matt Williams, Michael Philipp, Anja Roemer, Ross Hebden   +4 more
wiley   +1 more source

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source