Results 91 to 100 of about 72,312 (262)

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Interventions for pre‐school children in foster care: A systematic review of the foster carer and system level outcomes from randomised controlled trials

open access: yesJCPP Advances, EarlyView.
Abstract Background Children in foster care are at increased risk of experiencing cognitive, emotional and behavioural difficulties. There is a window of opportunity for early intervention associated with developmental sensitivity in the early years. Foster carers and the systems supporting them play a central role in intervention and support for the ...
Camilla Biggs   +6 more
wiley   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

open access: yesJCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista   +5 more
wiley   +1 more source

Intersection of Aging and Particulate Matter 2.5 Exposure in Real World: Effects on Inflammation and Endocrine Axis Activities in Rats

open access: yesInternational Journal of Endocrinology
Exposure to particulate matter 2.5 (PM2.5) is detrimental to multiple organ systems. Given the factor that aging also alters the cellularity and response of immune system and dysfunction of hypothalamic-pituitary-adrenal, -gonad and -thyroid axes, it is ...
Cuiying Liu   +7 more
doaj   +1 more source

The imaginary divide between mental and “physical” health: Dismantling dualism and reductionism to address a monumental mistake in medicine

open access: yesJCPP Advances, EarlyView.
Abstract Given the importance of the link between mental and other medical conditions, JCPP Advances organized a special issue on the topic; yet since then, very few papers have focused on this area. As such, this editorial perspective aims not only to highlight the link between mental and other medical conditions, but also to (1) explore the origins ...
Nicholas Fabiano   +8 more
wiley   +1 more source

Offspring Global DNA Methylation is not Affected by Parental Developmental Stress Experience in a Passerine Species

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Rapid phenotypic change may be mediated by intergenerational transmission of early developmental experiences. In birds, exposure to glucocorticoids during early development can alter global DNA methylation and gene expression. However, DNA methylation is labile, and it is currently unclear whether the impacts of stress suffered during juvenile
Anna Miltiadous   +5 more
wiley   +1 more source

Sex‐specific associations between potentially traumatic events and cardiovascular disease in middle‐aged and older adults

open access: yesJournal of Traumatic Stress, EarlyView.
Abstract Potentially traumatic events (PTEs) are associated with cardiovascular disease (CVD) in aging populations. Despite sex differences in PTE exposure and CVD incidence, no study has examined sex‐specific associations between PTEs and CVD in the same sample of middle‐aged and older adults.
Jeanine I. Nasser   +5 more
wiley   +1 more source

Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan

open access: yesJEADV Clinical Practice, EarlyView.
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi   +4 more
wiley   +1 more source

The Association Between Stress‐Induced Hyperglycemia Ratio and Increased Urinary Albumin Excretion in Patients With Hypertension: A Population‐Based Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The stress hyperglycemia ratio (SHR), a novel marker reflecting relative hyperglycemia, has been increasingly recognized for its prognostic value in cardiovascular and metabolic diseases. However, its association with early renal damage in hypertensive patients remains underexplored.
Kai‐Jun Zhang   +5 more
wiley   +1 more source

Safety profile comparison of intra‐articular corticosteroids, hyaluronic acid, platelet‐rich plasma, and cell‐based injections for knee osteoarthritis: A systematic review and meta‐analysis by the ESSKA Orthobiologics Initiative

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim was to compare the safety profiles of corticosteroids (CS), hyaluronic acid (HA), blood‐derived products based on platelet concentrates (for simplicity indicated as PRP ‐ platelet‐rich plasma ‐ being PRP the most common product), and cell‐based therapies (namely products exploiting the therapeutic function of mesenchymal ...
Alessandro Bensa   +8 more
wiley   +1 more source

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