Results 71 to 80 of about 72,312 (262)

Peripheral inflammatory markers and metabolic profiles in temporal lobe epilepsy and functional dissociative seizures

Epileptic Disorders, EarlyView.
Abstract Background Temporal lobe epilepsy (TLE) and functional dissociative seizures (FDS) are distinct conditions that share overlapping clinical, neuropsychiatric, and biological features, including depressive symptoms, obesity‐related metabolic dysregulation, and alterations in systemic inflammatory markers.
Betül Merd, Şeyma Benli, Fatmanur Merd, Meltem Sönmez, Füsun Ferda Erdoğan   +4 more
wiley   +1 more source

Psychological stress during wartime and its association with seizure‐related emergency department utilization

Epilepsia, EarlyView.
Abstract Objective Psychological stress is commonly reported as a seizure precipitant in epilepsy, yet evidence from major crises remains limited and inconsistent. We examined whether the October 2023 Israel–Hamas conflict affected acute seizure‐related healthcare utilization among adults with epilepsy. Methods We conducted a retrospective cohort study
Anda Eilam, Mahdi Arar, Yacov Balash, Volodymyr Samogalskyi, Merav Greenstein, Michael Zouari, Nadejda Khmelev   +6 more
wiley   +1 more source

The fetal and neonatal hypothalamic–pituitary–adrenal axis [PDF]

Archives of Disease in Childhood - Fetal and Neonatal Edition, 2000
The hypothalamus, pituitary, and adrenal glands are dynamic endocrine organs during fetal development.1-3 The adrenal glands, in particular, exhibit remarkable transformation in size, morphology, and function during the prenatal and neonatal periods.2 3 It is now recognised that normal development of the hypothalamic–pituitary–adrenal (HPA) axis is ...
openaire   +2 more sources

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

THE HYPOTHALAMIC‐PITUITARY‐ADRENAL AXIS IN INFANTILE MALNUTRITION

Clinical Endocrinology, 1990
SUMMARYWe studied the circadian rhythm and the response of the hypothalamic‐pituitary‐adrenal (HPA) axis to ovine corticotrophin releasing hormone (oCRH) stimulation and dexamethasone suppression in 32 children with grade II‐III marasmus. Children were studied prior to and after nutritional rehabilitation.
MALOZOWSKI, SAUL, Muzzo, Santiago, Burrows, Raquel, Leiva Balich, Laura, Loriaux, Lynn, CHROUSOS, GEORGE, WINTERER, JORG, Cassorla Goluboff, Fernando   +7 more
openaire   +3 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient

Case Reports in Endocrinology, 2018
The hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-gonadal (HPG) axis are very sensitive and can be affected by external factors like stress, starvation, and medication.
Lubna Bashir Munshi, Yumiko Tsushima, Kwan Cheng, Maria Brito   +3 more
doaj   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source