Results 51 to 60 of about 96,734 (308)

Progressive onset of adrenal insufficiency and hypogonadism of pituitary origin caused by a complex genetic rearrangement within DAX-1

, 2002
DAX-1 [dosage-sensitive sex reversal, adrenal hypoplasia congenital (AHC) critical region on the X chromosome, gene 11 is a transcription factor expressed in the adrenal gland and at all levels of the gonadotrope axis.
Gaillard, R.C., Schorderet, D., Schorderet, D, Jameson, J.L., Pralong, F.P., Gaillard, RC, Fiaux, M., Achermann, JC, Salvi, R, Achermann, J.C., Gomez, F, Fiaux, M, Pralong, FP, Jameson, JL, Salvi, R., Gomez, F.   +15 more
core   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Research progress in the correlation between chronic stress and ovarian dysfunction

Shanghai Jiaotong Daxue xuebao. Yixue ban
The ovary is an important reproductive organ for women. Decreased ovarian function not only affects the reproductive capabilities, but also leads to the decline of women′s quality of life.
WEI Liutong, LAI Dongmei
doaj   +1 more source

Superposição entre depressão atípica, doença afetiva sazonal e síndrome da fadiga crônica Overlap between atypical depression, seasonal affective disorder and chronic fatigue syndrome

Brazilian Journal of Psychiatry, 2007
OBJETIVO: Foram revisados estudos que descrevem que as alterações na função do eixo hipotálamo-hipófise-adrenal são relacionadas com o estado psicopatológico em depressão.
Mario Francisco Juruena, Anthony James Cleare   +1 more
doaj   +1 more source

Effect of date seed (Phoenix dactylifera) supplementation as functional food on cardiometabolic risk factors, metabolic endotoxaemia and mental health in patients with type 2 diabetes mellitus: a blinded randomised controlled trial protocol

BMJ Open, 2023
Introduction Recently, the improvement of chronic hyperglycaemia-related damage of type 2 diabetes mellitus (T2DM) through functional food consumption has attracted the attention of many clinicians.
Mehdi Mohammadi Zadeh, Parvin Dehghan, Zahra Eslami   +2 more
doaj   +1 more source

Origin of ultradian pulsatility in the hypothalamic-pituitary-adrenal axis

, 2009
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates the circulating levels of vital glucocorticoid hormones. The activity of the HPA axis is characterized not only by a classic circadian rhythm but also by an ultradian
Terry, JR, Lightman, S.L., Walker, J.J., Walker, JJ, Terry, J.R.; id_orcid, Lightman, SL   +5 more
core   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

Persistent dizziness and recurrent syncope due to HIV-associated Addison’s disease: Case report from a resource-limited setting

Southern African Journal of HIV Medicine, 2012
Addison’s disease or primary adrenal insufficiency is a well-recognised fatal endocrine condition among HIV-infected patients. HIV infection is associated with adrenal gland destruction and profound disruption of the hypothalamic-pituitary adrenal axis ...
D Kibirige, R Ssekitoleko, E Mutebi
doaj   +1 more source

Neonatal overfeeding disrupts pituitary ghrelin signalling in female rats long-term; Implications for the stress response. [PDF]

PLoS ONE, 2017
The hypothalamic-pituitary-adrenal (HPA) axis responses to psychological stress are exacerbated in adult female but not male rats made obese due to overfeeding in early life.
Luba Sominsky, Ilvana Ziko, Sarah J Spencer   +2 more
doaj   +1 more source

The hypothalamic-pituitary-adrenal axis in anorexia nervosa [PDF]

Psychiatry Research, 1996
Studies examining the function of the hypothalamic-pituitary-adrenal (HPA) axis in anorexia nervosa are reviewed. A principal finding is that of hypercortisolism, associated with increased central corticotropin-releasing hormone levels and normal circulating levels of adrenocorticotropic hormone. Similarities between neuroendocrine findings in anorexia
Licinio, Júlio, Wong, Ma-Li, Gold, Philip W.   +2 more
openaire   +2 more sources