Results 31 to 40 of about 130,466 (307)
This paper analyzes a four-dimensional model of the hypothalamic-pituitary-adrenal (HPA) axis that includes the influence of the glucocorticoid receptor in the pituitary.
Kaslik, Eva +2 more
core +1 more source
Hypothalamic-Pituitary-Adrenal (HPA) axis [PDF]
Increased adrenocortical secretion of hormones, primarily cortisol in depression, is one of the most consistent findings in neuropsychiatry. The maintenance of the internal homeostatic state of an individual is facilitated by the ability to circulate glucocorticoids to exert negative feedback on the secretion of hypothalamic-pituitary-adrenal (HPA ...
Young, Allan H., Juruena, Mario F.
openaire +3 more sources
Influence of mirtazapine on salivary cortisol in depressed patients [PDF]
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C. +3 more
core +1 more source
Is There an Association between Work Stress and Diurnal Cortisol Patterns? Findings from the Whitehall II Study. [PDF]
The evidence on whether there is work stress related dysregulation of the hypothalamic-pituitary-adrenal axis is equivocal. This study assessed the relation between work stress and diurnal cortisol rhythm in a large-scale occupational cohort, the ...
Brunner, EJ, Kumari, M, Liao, J
core +4 more sources
Depressão e estresse: existe um endofenótipo? Depression and stress: is there an endophenotype?
OBJETIVO: Revisar os achados recentes sobre a relação entre estresse, eixo hipotálamo-pituitária-adrenal e depressão, na tentativa de explicar um endofenótipo de vulnerabilidade para o desenvolvimento da depressão.
Andrea Feijo Mello +6 more
doaj +1 more source
Critical roles of endogenous glucocorticoids for disease tolerance in malaria
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien +4 more
core +1 more source
Decreased Interleukin-4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress [PDF]
It has been demonstrated that immobilization (IMO) stress affects neuroimmune systems followed by alterations of physiology and behavior. Interleukin-4 (IL-4), an anti-inflammatory cytokine, is known to regulate inflammation caused by immune challenge ...
An, Kyungeh +4 more
core +4 more sources
Estrogenic Action in Stress-Induced Neuroendocrine Regulation of Energy Homeostasis
Estrogens are among important contributing factors to many sex differences in neuroendocrine regulation of energy homeostasis induced by stress. Research in this field is warranted since chronic stress-related psychiatric and metabolic disturbances ...
Kristen N. Krolick, Haifei Shi
doaj +1 more source
The hypothalamic-pituitary-adrenal axis in critical illness [PDF]
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Allolio, B. +3 more
core
Pituitary-adrenal axis in Prader Willi syndrome [PDF]
Purpose: Prader Willi syndrome (PWS) is a rare genetic condition that has concurrent endocrinological insufficiencies. The presence of growth hormone deficiency has been well documented, but adrenal insufficiency (AI) is not widely reported. A review was
Edgar, Olivia S. +2 more
core +2 more sources

