Results 41 to 50 of about 96,734 (308)

Estrogenic Action in Stress-Induced Neuroendocrine Regulation of Energy Homeostasis

Cells, 2022
Estrogens are among important contributing factors to many sex differences in neuroendocrine regulation of energy homeostasis induced by stress. Research in this field is warranted since chronic stress-related psychiatric and metabolic disturbances ...
Kristen N. Krolick, Haifei Shi
doaj   +1 more source

Modulation of the hypothalamic-pituitary-adrenal axis of an Arctic-breeding polygynandrous songbird, the Smith's longspur, Calcarius pictus

, 2003
To successfully reproduce in the Arctic, birds must modulate their neuroendocrine and behavioural systems. These adjustments include an attenuation of the stress responsiveness of the hypothalamic-pituitary-adrenal (HPA) axis to external stimuli and a ...
Wingfield, John C, Meddle, Simone L; id_orcid, Richardson, Matthew I, Owen-Ashley, Noah T   +3 more
core   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Impact of stress on male fertility: role of gonadotropin inhibitory hormone

Frontiers in Endocrinology
Studies have implicated oxidative stress-sensitive signaling in the pathogenesis of stress-induced male infertility. However, apart from oxidative stress, gonadotropin inhibitory hormone (GnIH) plays a major role.
Adeyemi F. Odetayo, Adeyemi F. Odetayo, Roland E. Akhigbe, Roland E. Akhigbe, Grace E. Bassey, Moses A. Hamed, Moses A. Hamed, Moses A. Hamed, Luqman A. Olayaki   +8 more
doaj   +1 more source

Modeling pulsativity in the hypothalamic–pituitary–adrenal hormonal axis

Scientific Reports, 2022
A new mathematical model for biological rhythms in the hypothalamic–pituitary–adrenal (HPA) axis is proposed. This model takes the form of a system of impulsive time-delay differential equations which include pulsatile release of adrenocorticotropin ...
Alexander N. Churilov, John G. Milton
doaj   +1 more source

The Local Neuropeptide System of Keratinocytes

Biomedicines, 2021
Neuropeptides have been known for over 50 years as chemical signals in the brain. However, it is now well established that the synthesis of this class of peptides is not restricted to neurons. For example, human skin not only expresses several functional
Nicola Cirillo
doaj   +1 more source

The effect of therapeutic glucocorticoids on the adrenal response in a randomized controlled trial in patients with rheumatoid arthritis

, 2005
Objective To measure the effect of low-dose systemic glucocorticoid treatment on the adrenal response to adrenocorticotropic hormone (ACTH) in patients with rheumatoid arthritis (RA).
Wollheim, Frank, Roger Hällgren, Wollheim, Frank A, WOLLHEIM, F, Björck, Ewa, Björck, E, Hickey, Sarah H, Herman Mielants, Mielants, Herman, Mielants, H, John R. Kirwan, Persson, T, Persson, Tore, Hickey, SH, Wollheim, Frank,, Kirwan, JR, Ewa Björck, Hällgren, Roger,, Hällgren, R, Kirwan, John R, Frank A. Wollheim, Wollheim, FA, Tore Persson, Lund University., Sarah H. Hickey   +24 more
core   +1 more source

Impairment of adrenocortical function associated with increased plasma tumor necrosis factor-alpha and interleukin 6 concentrations in African trypanosomiasis [PDF]

, 1994
African sleeping sickness (SS) is a severe, potentially lethal parasitic disease. The treatments of choice are the antiparasitic agents suramin, which is adrenotoxic, and/or melarsoprol. We evaluated the functional integrity of the hypothalamic-pituitary-
Winkelmann, W., Reincke, M, Allolio, B., Siekmann, L., Heppner, C, Arlt, W, Petzke, F, Arlt, W., Mbulamberi, D, Vollmer, D, Chrousos, G. P., Allolio, B, Siekmann, L, Vollmer, D., Heppner, C., Mbulamberi, D., Winkelmann, W, Reincke, Martin, Petzke, F., Chrousos, G P   +19 more
core   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Stress-Induced Neurodegeneration: The Potential for Coping as Neuroprotective Therapy

American Journal of Alzheimer's Disease and Other Dementias, 2020
Stress responses are essential for survival, but become detrimental to health and cognition with chronic activation. Chronic hypothalamic-pituitary-adrenal axis release of glucocorticoids induces hypothalamic-pituitary-adrenal axis dysfunction and ...
Shelby A. Kline MS, Michael S. Mega MD, PhD   +1 more
doaj   +1 more source