Results 31 to 40 of about 151,312 (311)
Characterization of Fatty Acid Composition Underlying Hypothalamic Inflammation in Aged Mice
Molecules, 2020 Degenerative diseases, which can develop during aging, are underlined by inflammatory processes. Hypothalamic inflammation triggered by elevation in circulating fatty acid levels is directly coupled to metabolic disorders.
Ye Jin Kim +4 more
doaj +1 more source
Cell Death and Disease, 2022 Palmitic acid (PA) is significantly increased in the hypothalamus of mice, when fed chronically with a high-fat diet (HFD). PA impairs insulin signaling in hypothalamic neurons, by a mechanism dependent on autophagy, a process of lysosomal-mediated ...
Yenniffer Ávalos +24 more
doaj +1 more source
Hypothalamic inflammation in obesity and metabolic disease [PDF]
Journal of Clinical Investigation, 2017 Over the last years, hypothalamic inflammation has been linked to the development and progression of obesity and its sequelae. There is accumulating evidence that this inflammation not only impairs energy balance but also contributes to obesity-associated insulin resistance.
Jais, A., Brüning, J.
openaire +3 more sources
Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health [PDF]
, 2017 Daily interactions between the hypothalamic circadian clock at the suprachiasmatic nucleus (SCN) and peripheral circadian oscillators regulate physiology and metabolism to set temporal variations in homeostatic regulation.
Diego A. Golombek +6 more
core +2 more sources
Imaging of the pituitary: Recent advances
Indian Journal of Endocrinology and Metabolism, 2011 Pituitary lesions, albeit relatively infrequent, can significantly alter the quality of life. This article highlights the role of advanced imaging modalities in evaluating pituitary-hypothalamic axis lesions.
Vikas Chaudhary, Shahina Bano
doaj +1 more source
Nutrition and Metabolic Insights, 2020 Nowadays, much attention has been paid to the link between gut microbiota and brain. The beneficial metabolic effects of probiotics and prebiotics in several diseases such as diabetes and obesity have been reported.
Elaheh-Sadat Hosseinifard +3 more
doaj +1 more source
Applied Sciences, 2022 Among potential factors affecting the surgical resection in pituitary tumors, the role of tumor three-dimensional (3D) features is still unexplored. The aim of this study is to introduce the use of 3D virtual modeling for geometrical and morphological ...
Laura Cercenelli +7 more
doaj +1 more source
Trypanosoma brucei brucei invasion and T-cell infiltration of the brain parenchyma in experimental sleeping sickness: timing and correlation with functional changes [PDF]
, 2016 Background: The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has ...
Bentivoglio, Marina +8 more
core +4 more sources
Cell ReportsSummary: Aging-associated neurodegeneration underlies various neurological diseases; however, the neurocrine basis remains poorly understood. Here, we investigate the role of parathymosin (PTMS), a secretory protein with nuclear functions that has ...
Hyun-Gug Jung +7 more
doaj +1 more source
STRESS AS PREDISPOSING FACTOR OF SOME CHRONIC DISEASES INCLUDING PERIODONTAL DISEASE
Journal of Dentistry Indonesia, 2006 Stress is hypothesized as a common pathway for several related chronic diseases of man. Psychosocial stress as modified by perceptions and coping by patients can lead to physical processes.
Dewi-Nurul M Dewi-Nurul +1 more
doaj +1 more source