Results 51 to 60 of about 444,141 (265)

GABAergic Projections from Lateral Hypothalamus to Paraventricular Hypothalamic Nucleus Promote Feeding

Journal of Neuroscience, 2015
Lesions of the lateral hypothalamus (LH) cause hypophagia. However, activation of glutamatergic neurons in LH inhibits feeding. These results suggest a potential importance for other LH neurons in stimulating feeding.
Zhaofei Wu, Eun Ran Kim, Hao Sun, Yuanzhong Xu, Leandra R. Mangieri, De-Pei Li, Hui-Lin Pan, Yong Xu, Benjamin R. Arenkiel, Qing-Chun Tong   +9 more
semanticscholar   +1 more source

Lesions of the Hypothalamic Paraventricular Nucleus and Norepinephrine Turnover in Rats.

Endocrinologia Japonica, 1989
The effects of bilateral lesions of the hypothalamic paraventricular nuclei (PVN), of rats with a mean weight of 260 g body, on eating habits and body weight, as well as on sympathetic nervous system (SNS) activity in interscapular brown adipose tissue (IBAT) were investigated.
YOSHIDA, TOSHIHIDE, YOSHIOKA, KEIJI, NISHIOKA, HITOSHI, KONDO, MOTOHARU   +3 more
openaire   +3 more sources

The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus

Science Advances, 2020
A hypothalamic neuronal circuit mediates circadian-regulated wakefulness in mice. In mammals, the daily rhythms of physiological functions are timed by the central circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Although
Daisuke Ono, Yasutaka Mukai, Chijung Hung, Srikanta Chowdhury, T. Sugiyama, A. Yamanaka   +5 more
semanticscholar   +1 more source

Leptin Activates Oxytocin Neurons of the Hypothalamic Paraventricular Nucleus in Both Control and Diet-Induced Obese Rodents

PLoS ONE, 2013
The adipocyte-derived hormone leptin acts in the brain to reduce body weight and fat mass. Recent studies suggest that parvocellular oxytocin (OXT) neurons of the hypothalamic paraventricular nucleus (PVN) can mediate body weight reduction through ...
M. Perelló, J. Raingo
semanticscholar   +1 more source

Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances [PDF]

, 2007
The hypothalamic melanocortin system is crucial for the control of appetite and body weight. Two of the five melanocortin receptors, MC3R and MC4R are involved in hypothalamic control of energy homeostasis, with the MC4R having the major influence. It is
Hisadome, Kazunari, Michael L. J. Ashford, Smith, Mark A., Helen Heffron, Mark A. Smith, Al-Qassab, Hind, Kazunari Hisadome, Withers, Dominic J., Hind Al‐Qassab, Dominic J. Withers, Ashford, Michael L. J.; id_orcid, Heffron, Helen   +11 more
core   +1 more source

Synaptic output from suprachiasmatic nucleus cholecystokinin neurons regulates locomotor rhythmicity

Frontiers in Neuroscience
BackgroundThe mammalian suprachiasmatic nucleus (SCN) serves as the master circadian pacemaker, which coordinates daily behavioral and physiological rhythms through functionally diverse neuronal subtypes. Cholecystokinin (CCK) is expressed in a subset of
Wanli Chen, Wanli Chen, Wanli Chen, Wanli Chen, Zhixiong Ma, Zhixiong Ma, Zhixiong Ma, Xiaoqing Hao, Xiaoqing Hao, Xiaoqing Hao, Shikang Guan, Shikang Guan, Shikang Guan, Xin Diao, Xin Diao, Xin Diao, Yuehong Huang, Yuehong Huang, Yuehong Huang, Yuehong Huang, Ruogu Liu, Ruogu Liu, Ruogu Liu, Ruogu Liu, Zhengran Li, Zhengran Li, Zhengran Li, Zhengran Li, Bingbing Xue, Bingbing Xue, Bingbing Xue, Tongfei A. Wang, Tongfei A. Wang, Tongfei A. Wang, Tongfei A. Wang   +34 more
doaj   +1 more source

The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments [PDF]

Archives of Endocrinology and Metabolism
The hypothalamus is a master regulator of energy balance in the body. First-order hypothalamic neurons localized in the arcuate nucleus sense systemic signals that indicate the energy stores in the body.
Bruna Bombassaro, Eliana P. Araujo, Licio A. Velloso   +2 more
doaj   +1 more source

Hypothalamic paraventricular nucleus activation contributes to neurohumoral excitation in rats with heart failure [PDF]

Regenerative Medicine Research, 2014
Heart failure (HF) is a serious cardiovascular disease and is characterized by exaggerated sympathetic activity. In this paper, we review these limited studies, with particular emphasis on examining the role of the paraventricular nucleus (PVN) in the ...
Kang Yu-Ming, Yang Qing, Yu Xiao-Jing, Qi Jie, Zhang Yan, Li Hong-Bao, Su Qing, Zhu Guo-Qing   +7 more
doaj   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Circadian rhythm mechanism in the suprachiasmatic nucleus and its relation to the olfactory system

Frontiers in Neural Circuits
Animals need sleep, and the suprachiasmatic nucleus, the center of the circadian rhythm, plays an important role in determining the timing of sleep. The main input to the suprachiasmatic nucleus is the retinohypothalamic tract, with additional inputs ...
Yusuke Tsuno, Michihiro Mieda
doaj   +1 more source