Results 61 to 70 of about 21,484 (235)

The hypothalamic paraventricular nucleus may not be at the heart of sympathetic outflow

The Journal of Physiology, 2013
Heart failure (HF) is associated with activation of various neurohumoral factors including the renin–angiotensin–aldosterone and sympathetic nervous systems. In HF patients, elevated sympathetic nerve activity (SNA) is reflected by increased whole body, as well as regional (e.g. cardiac and renal) noradrenaline spillover (Kaye et al. 1994; Petersson et
Sean D, Stocker, Kevin D, Monahan, Lawrence I, Sinoway   +2 more
openaire   +3 more sources

c-Fos expression in the hypothalamic paraventricular nucleus after a single treatment with a typical haloperidol and nine atypical antipsychotics: a pilot study

Endocrine Regulations, 2018
Objective. The aim of the present study was to find out whether acute effect of different doses of selected antipsychotics including aripiprazole (ARI), amisulpride (AMI), asenapine (ASE), haloperidol (HAL), clozapine (CLO), risperidone (RIS), quetiapine
Kiss Alexander
doaj   +1 more source

Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring. [PDF]

PLoS ONE, 2009
Hypothalamic systems which regulate appetite may be permanently modified during early development. We have previously reported hyperphagia and increased adiposity in the adult offspring of rodents fed an obesogenic diet prior to and throughout pregnancy ...
Shona L Kirk, Anne-Maj Samuelsson, Marco Argenton, Hannah Dhonye, Theodosis Kalamatianos, Lucilla Poston, Paul D Taylor, Clive W Coen   +7 more
doaj   +1 more source

The impact of breast milk relaxin 2, oxytocin, and insulin‐like peptide 3 on neonatal growth parameters in early life

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1479-1487, June 2026.
Abstract Objectives This study aims to quantify the levels of relaxin 2 (RLX2), oxytocin (OXT), and insulin‐like peptide 3 (INSL3) in colostrum (postpartum days 1–5, Visit 1) and mature breast milk (postpartum days 21–35, Visit 2), and to evaluate their associations with neonatal growth outcomes.
Hakan Doneray, Ayse Ozden, Guzide Tavlas, Halil Ibrahim Ozkan   +3 more
wiley   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris

Integrative Zoology, EarlyView.
Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli, Al‐Sayed Al‐Soudy, Mariangela Norcia, Stefania Galdiero, Sara Palladino, Emanuela Cirillo, Gianluca Polese, Anna Di Cosmo   +7 more
wiley   +1 more source

Effects of stresscopin on rat hypothalamic paraventricular nucleus neurons in vitro. [PDF]

PLoS ONE, 2013
The effects of stresscopin (SCP) on rat paraventricular nucleus (PVN) neurons were examined using whole-cell patch-clamp recordings and single-cell reverse-transcription multiplex polymerase chain reaction (SC-RT-mPCR) techniques.
Chun-Ping Chu, Wen-Zhe Jin, Yan-Hua Bing, Qing-Hua Jin, Hiroshi Kannan, De-Lai Qiu   +5 more
doaj   +1 more source

Microglia‐Mediated Neuroimmune Response Regulates Cardiac Remodeling After Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Sympathetic hyperactivity contributes to pathological remodeling after myocardial infarction (MI). However, the mechanisms underlying the increase in sympathetic activity remain unknown.
Menglong Wang, Jishou Zhang, Zheng Yin, Wen Ding, Mengmeng Zhao, Jianfang Liu, Yao Xu, Shuwan Xu, Wei Pan, Cheng Wei, Hong Jiang, Jun Wan   +11 more
doaj   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Cellular Localization of Orexin 1 Receptor in Human Hypothalamus and Morphological Analysis of Neurons Expressing the Receptor

Biomolecules, 2023
The orexin system is related to food behavior, energy balance, wakefulness and the reward system. It consists of the neuropeptides orexin A and B, and their receptors, orexin 1 receptor (OX1R) and orexin 2 receptor (OX2R). OX1R has selective affinity for
Konstantina Vraka, Dimitrios Mytilinaios, Andreas P. Katsenos, Anastasios Serbis, Stavros Baloyiannis, Stefanos Bellos, Yannis V. Simos, Nikolaos P. Tzavellas, Spyridon Konitsiotis, Patra Vezyraki, Dimitrios Peschos, Konstantinos I. Tsamis   +11 more
doaj   +1 more source