Results 1 to 10 of about 74,149 (232)

<i>E. coli</i> genetically modified for purine nucleobase release promotes butyrate generation and colonic wound healing during DSS insult. [PDF]

Gut Microbes
The gut microbiota transforms energy stored as undigestible carbohydrates into a remarkable number of metabolites that fuel intestinal bacterial communities and the host tissue.
Lee JS, Kao DJ, Worledge CS, Villamaria ZF, Wang RX, Welch NM, Kostelecky RE, Colgan SP.   +7 more
europepmc   +2 more sources

Brain network and energy imbalance in Parkinson's disease: linking ATP reduction and α-synuclein pathology. [PDF]

Front Mol Neurosci
Parkinson’s disease (PD) involves the disruption of brain energy homeostasis. This encompasses broad-impact factors such as mitochondrial dysfunction, impaired glycolysis, and other metabolic disturbances, like disruptions in the pentose phosphate ...
Watanabe H, Shima S, Kawabata K, Mizutani Y, Ueda A, Ito M.   +5 more
europepmc   +2 more sources

The metabolic engineering of Escherichia coli for the high-yield production of hypoxanthine. [PDF]

Microb Cell Fact
Background Hypoxanthine, prevalent in animals and plants, is used in the production of food additives, nucleoside antiviral drugs, and disease diagnosis.
Zhao S, Shi T, Li L, Chen Z, Li C, Yu Z, Sun P, Xu Q.   +7 more
europepmc   +2 more sources

Establishment and optimization of a novel mouse model of hyperuricemic nephropathy. [PDF]

Ren Fail
Hyperuricemia is a metabolic disorder characterized by elevated serum uric acid levels. Soluble urate can activate immune responses, and the excessive accumulation of urate in the kidneys results in hyperuricemic nephropathy (HN). However, the lack of an
Wang J, Chen R, Wu K, Mo J, Li M, Chen Z, Wang G, Zhou P, Lan T.   +8 more
europepmc   +2 more sources

The Effect of Two Weeks of High-intensity Interval Training on Salvage nucleotide pathway [PDF]

فیزیولوژی ورزش و فعالیت بدنی, 2022
Purpose: The effects of exercise adaptation on improving the purine nucleotides components are inevitable, and physical activity improves the purine nucleotide salvage pathway.
Abbas Ghanbari Niaki, Rouhollah Haghshenas Gatabi   +1 more
doaj   +1 more source

Assessing Meat Freshness via Nanotechnology Biosensors: Is the World Prepared for Lightning-Fast Pace Methods?

Biosensors, 2023
In the rapidly evolving field of food science, nanotechnology-based biosensors are one of the most intriguing techniques for tracking meat freshness.
Wen Xia Ling Felicia, Kobun Rovina, Nasir Md Nur ‘Aqilah, Joseph Merillyn Vonnie, Koh Wee Yin, Nurul Huda   +5 more
doaj   +1 more source

Characterizing nanoplastics‐induced stress and its SERS fingerprint in an intestinal membrane model

Nano Select, 2021
Epithelium membranes provide important barrier functions, and it is important to understand how nanoparticle (NP) exposure affects their barrier function.
Qianyun Zhang, Björn M. Reinhard
doaj   +1 more source

Metabolite Ratios as Quality Indicators for Pre-Analytical Variation in Serum and EDTA Plasma

Metabolites, 2021
In clinical diagnostics and research, blood samples are one of the most frequently used materials. Nevertheless, exploring the chemical composition of human plasma and serum is challenging due to the highly dynamic influence of pre-analytical variation ...
Sven Heiling, Nadine Knutti, Franziska Scherr, Jörg Geiger, Juliane Weikert, Michael Rose, Roland Jahns, Uta Ceglarek, André Scherag, Michael Kiehntopf   +9 more
doaj   +1 more source

Downregulation of Peroxidase Activity of Platinum Cube Enables Minute–Time Scale Colorimetric Signaling of Hypoxanthine for Fish Freshness Monitoring

Foods, 2023
Due to its unique biological composition, aquatic products, especially fish, are extremely perishable compared to other muscle products. Herein, we proposed an artificial nanozyme-based colorimetric detection of hypoxanthine (Hx), the indicator of fish ...
Xiaoming Ma, Tingting Feng, Peng Zhang, Hui Zhang, Xuan Hu, Yuying Yang, Zhen Wang, Huifang Zhang, Dong Peng, Xun Li, Jianguo Xu   +10 more
doaj   +1 more source

The combination of microbiological, biochemical, and quality index methods in quality evaluation of pacific white shrimps (Litopenaeus vannamei) preserved at 0°C

Vietnam Journal of Science, Technology and Engineering, 2022
In this study, the sensory, microbiological, and biochemical qualities were used to examine the quality of Pacific white shrimps (Litopenaeus vannamei) preserved at 0°C during a 10-day period.
Nhat Tam Le, Nguyen Que Anh Huynh, Nhu Khue Doan, Thuy Xuan Uyen Phan, Ba Thanh Nguyen, Sao Mai Dam, Thi Van Thi Tran, Le phuong Lien Nguyen, Van Hai Chu, Huynh Anh Vu Truong   +9 more
doaj   +1 more source