Results 21 to 30 of about 64,168 (232)
Foods, 2023 Due to its unique biological composition, aquatic products, especially fish, are extremely perishable compared to other muscle products. Herein, we proposed an artificial nanozyme-based colorimetric detection of hypoxanthine (Hx), the indicator of fish ...
Xiaoming Ma +10 more
doaj +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Differential regulation of hypoxanthine and xanthine by obesity in a general population
Journal of Diabetes Investigation, 2020 Aims/Introduction Uric acid is synthesized by oxidation of hypoxanthine and xanthine using a catalyzing enzyme, xanthine oxidoreductase (XOR), which can be a source of reactive oxygen species.
Masato Furuhashi +12 more
doaj +1 more source
Metabolite Ratios as Quality Indicators for Pre-Analytical Variation in Serum and EDTA Plasma
Metabolites, 2021 In clinical diagnostics and research, blood samples are one of the most frequently used materials. Nevertheless, exploring the chemical composition of human plasma and serum is challenging due to the highly dynamic influence of pre-analytical variation ...
Sven Heiling +9 more
doaj +1 more source
Toxicological effects of hypoxanthine on Heterosigmaakashiwo: Mechanism of growth inhibition and change in hemolytic toxin content [PDF]
, 2021 Heterosigmaakashiwo is an algal species that causes harmful algal blooms (HABs) with strong hemolytic toxicity on coastal aquatic organisms. This study investigated the mechanism of growth inhibition and changes in hemolytic toxin contents in algal ...
Qiming Jimmy Yu +5 more
core +1 more source
Characterizing nanoplastics‐induced stress and its SERS fingerprint in an intestinal membrane model
Nano Select, 2021 Epithelium membranes provide important barrier functions, and it is important to understand how nanoparticle (NP) exposure affects their barrier function.
Qianyun Zhang, Björn M. Reinhard
doaj +1 more source
Biosensors, 2023 In the rapidly evolving field of food science, nanotechnology-based biosensors are one of the most intriguing techniques for tracking meat freshness.
Wen Xia Ling Felicia +5 more
doaj +1 more source
Surface-Enhanced Raman Analysis of Uric Acid and Hypoxanthine Analysis in Fractionated Bodily Fluids
Nanomaterials, 2023 In recent years, the disease burden of hyperuricemia has been increasing, especially in high-income countries and the economically developing world with a Western lifestyle. Abnormal levels of uric acid and hypoxanthine are associated with many diseases,
Furong Tian +4 more
doaj +1 more source
Renal Failure, 2020 Background Lesch–Nyhan disease (LND) is a rare X-linked recessive inborn error of purine metabolism. Late diagnosis of LND may cause significant morbidity. LND cases have never been reported in Indonesia.
Cahyani Gita Ambarsari +6 more
doaj +1 more source
Biosensor measurement of purine release from cerebellar cultures and slices [PDF]
, 2010 We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Eason, Robert +5 more
core +1 more source