Results 111 to 120 of about 103,245 (286)

Cashew Nut Oil Improves Lipid Metabolism and Fat Liver Deposition in High‐Fat Diet‐Fed C57BL/6J Mice

Lipids, EarlyView.
Thirty C57BL/6J mice were fed a high‐fat diet for 12 weeks to induce metabolic changes. They were then switched to diets containing cashew nut oil, soybean oil, or lard for another 12 weeks. Soybean oil reduced blood glucose, total cholesterol, LDL cholesterol, triglycerides, and liver steatosis.
Marcella Duarte Villas Mishima, Andressa Ladeira Bernardes, Carlos Alexandre Pinheiro, Luisa Gouveia Lana, Iasmim Xisto Campos, Valéria Silva de Lana, Izabela Maria Montezano de Carvalho, Patrícia Fontes Pinheiro, Renata Celi Lopes Toledo, Ana Paula Dionísio, Helen Hermana Hermsdorff, Maria do Carmo Gouveia Peluzio   +11 more
wiley   +1 more source

Didanosine determination in diluted alkaline electrolyte by adsorptive stripping voltammetry at the mercury film electrode [PDF]

Journal of Electrochemical Science and Engineering, 2012
A stripping method for the determination of didanosine at the submicromolar concentration levels is described. The method is based on controlled adsorptive accumulation of didanosine at thin-film mercury electrode followed by a linear cyclic scan ...
PERCIO AUGUSTO MARDINI FARIAS, ARNALDO AGUIAR CASTRO, ANA ISA PEREZ CORDOVES   +2 more
doaj  

Insights on Regioselective Synthesis of Fused Thiazoles: Density Functional Theory Calculations, Local Reactivity Indices, and Molecular Electrostatic Potential Analysis

ChemistryOpen, EarlyView.
A regioselective synthesis of fused thiazoles was achieved via aza‐Michael cyclization of thiazolidinone derivatives with hydrazines or heteroaryl amines. Density functional theory, local reactivity indices, and molecular electrostatic potential mapping are used to explain selectivity.
Ghaferah H. Al‐Hazmi, Jehan Y. Al‐Humaidi, Sayed M. Riyadh, Mohamed S. M. Ahmed, Magdi E. A. Zaki, Awatif H. Alruwaili, Khaled A. Alanazi, Rajeh H. Almutairi, Sobhi M. Gomha   +8 more
wiley   +1 more source

First case of hereditary xanthinuria in a Moroccan family

PAMJ Clinical Medicine, 2019
The xanthinuria is a rare hereditary autosomal recessive disease. It is related to xanthine oxidase deficiency also known as xanthine dehydrogenase, an enzyme involved in the metabolism of purine bases.
Aicha Ezoubeiri, Asma Labaali, Naima Fdil, Jean-François Benoist, Laila Chabaa   +4 more
doaj   +1 more source

Insertional Tagging, Cloning, and Expression of the Toxoplasma gondii Hypoxanthine-Xanthine-Guanine Phosphoribosyltransferase Gene

Journal of Biological Chemistry, 1996
A nonhomologous integration vector was used to identify the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase (HXGPRT) gene by insertional mutagenesis.
R. Donald, D. Carter, B. Ullman, D. Roos
semanticscholar   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Strong, specific, monodentate G-C base pair recognition by N7-inosine derivatives in the pyrimidine•purine-pyrimidine triple-helical binding motif [PDF]

, 2017
The nucleoside analogs 7-(2′-deoxy-α-D-ribofuranosyl)hypoxanthine (β7H, 1), 7-(2′-deoxy-β-D-ribofuranosyl)hypoxanthine (β7H, 2) and 7-(2′-O-methyl-β-Dribofuranosyl)hypoxanthine (β7HOMe, 3) were prepared and incorporated into triplex forming ...
Leumann, Christian J., Marfurt, Judith, Parel, Serge P.   +2 more
core  

Reagentless Real‐Time ATP Monitoring with New DNA Aptamers

Small, EarlyView.
A new aptamer is discovered via in vitro selection that binds to adenosine triphosphate (ATP) with high affinity (KD = 0.7 µm) and rejects closely related analogs including adenosine diphosphate (ADP), adenosine monophosphate (AMP), and adenosine. A fluorescent molecular beacon based on the aptamer enables continuous analyte monitoring in cell culture ...
Adara Bacon, Obtin Alkhamis, Caleb Byrd, Jacob Perry, Juan Canoura, Yi Xiao   +5 more
wiley   +1 more source

Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging

Aging Cell, EarlyView.
Untargeted metabolomics reveals a unique cord plasma metabolic landscape versus adult. Age‐declining cord‐specific enriched metabolites are identified as antiaging candidates, with a 5‐compound formula validated in proof‐of‐experiments to extend lifespan and healthspan in human cells and C. elegans.
JiaYu Liu, Shuai Jiang, YanYan Shen, RuiBo Wang, Zhi Jin, YanQing Cao, JinLiang Li, YanHong Liu, Qi Qi, Yue Guo, YunYing Wang, BoYang Xie, JunCheng Li, AiPing Cao, Yao Wang, ChunYan Yan, QiuYing Han, YingJie Zhu, Jing Peng, FangTing Dong, Xin Pan, XinHua He, Tao Zhou, AiLing Li, Kun He, Na Wang, WeiNa Zhang, Qing Xia   +27 more
wiley   +1 more source

Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome

Orphanet Journal of Rare Diseases, 2007
Deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) activity is an inborn error of purine metabolism associated with uric acid overproduction and a continuum spectrum of neurological manifestations depending on the degree of the enzymatic
R. Torres, J. Puig
semanticscholar   +1 more source