Results 121 to 130 of about 92,945 (337)

Nucleotide degradation and production of hypoxanthine in some Indian marine and freshwater fishes [PDF]

, 1977
Changes in nucleotides and production of hypoxanthine in rohu (Labeo rohita), mrigal (Cihhrina mrigala) and common carp (Cyprinus carpio) during storage at 2-4°C were examined. Differences were observed between common carp and others.
Ramanath, S., Velankar, N.K.
core  

Evidence for a Modulatory Effect of a 12‐Week Pomegranate Juice Intervention on the Transcriptional Response in Inflammatory Bowel Disease Patients Reducing Fecal Calprotectin Levels: Findings From a Proof‐of‐Principle Study

Molecular Nutrition &Food Research, EarlyView.
This study investigated how pomegranate juice affects inflammation in patients with inflammatory bowel disease who are currently in remission. After 12 weeks of drinking pomegranate juice, patients showed reduced markers of intestinal inflammation.
Ilaria Minato, Pedro Mena, Luigi Ricciardiello, Eleonora Scaioli, Andrea Belluzzi, Enrica Rotondo, Eleonora Derlindati, Barbara Montanini, Costanza Michelini, Nicole Tosi, Vicente Agullò Garcià, Gianfranco Picone, Carlo Mengucci, Sara Dobani, Paloma Salamanca, Alice Rosi, Margherita Dall'Asta, Letizia Bresciani, Claudio Curti, Enzo Spisni, Alessandra Dei Cas, Alessandra Bordoni, Francisco A. Tomás‐Barberán, Lynnette R. Ferguson, Daniele Del Rio, Francesca Danesi   +25 more
wiley   +1 more source

Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli [PDF]

, 2018
Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination.
Achcar, Fiona, Barrett, Michael P., Goodyear, Carl S., Pountain, Andrew W., Rattigan, Kevin M., Regnault, Clement, Vincent, Isabel M.   +6 more
core   +3 more sources

Postprandial Metabolism, Inflammation, and Plasma Bile Acid Kinetics in a Rat Model: Implications for Translational Research

Molecular Nutrition &Food Research, EarlyView.
Sprague‐Dawley rats were used to investigate postprandial metabolic and inflammatory responses following the consumption of an energy‐dense meal. Time‐resolved plasma and liver analyses revealed fluctuations in bile acid levels, particularly cholic acid, along with changes in metabolic intermediates, oxylipins, and inflammatory markers.
Larissa Rodrigues, Carlos M. Donado‐Pestana, Tushar More, Mar Garcia‐Aloy, Gustavo M. Carneiro de Lima, Lucas X. Martins de Oliveira, Urska Vrhovsek, Karsten Hiller, Jarlei Fiamoncini   +8 more
wiley   +1 more source

Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome

Orphanet Journal of Rare Diseases, 2007
Deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) activity is an inborn error of purine metabolism associated with uric acid overproduction and a continuum spectrum of neurological manifestations depending on the degree of the enzymatic
R. Torres, J. Puig
semanticscholar   +1 more source

An Up‐to‐Date Review of Traditional Chinese Medicine in the Treatment of Atherosclerosis: Components, Mechanisms, and Therapeutic Potentials

Phytotherapy Research, EarlyView.
Traditional Chinese medicine in atherosclerosis: multi‐target modulation of pathogenesis. ABSTRACT Atherosclerosis is a chronic inflammatory disease and a major global health concern. In recent years, traditional Chinese medicines (TCMs) have demonstrated multi‐target therapeutic potential against atherosclerosis by modulating inflammatory responses ...
Dilaram Nijat, Qingzhe Zhao, Gulhasal Abdurixit, Jianhua He, Haipeng Liu, Jinyao Li   +5 more
wiley   +1 more source

Hydrothermally Synthesized Cerium Phosphate with Functionalized Carbon Nanofiber Nanocomposite for Enhanced Electrochemical Detection of Hypoxanthine

Chemosensors
This work presents the detection of hypoxanthine (HXA), a purine derivative that is similar to nucleic acids who overconsumption can cause health issues, by using hydrothermally synthesized cerium phosphate (CePO4) followed by a sonochemical approach for
Prashant K. Kasare, Sea-Fue Wang
doaj   +1 more source

Strong, specific, monodentate G-C base pair recognition by N7-inosine derivatives in the pyrimidine•purine-pyrimidine triple-helical binding motif [PDF]

, 2017
The nucleoside analogs 7-(2′-deoxy-α-D-ribofuranosyl)hypoxanthine (β7H, 1), 7-(2′-deoxy-β-D-ribofuranosyl)hypoxanthine (β7H, 2) and 7-(2′-O-methyl-β-Dribofuranosyl)hypoxanthine (β7HOMe, 3) were prepared and incorporated into triplex forming ...
Leumann, Christian J., Marfurt, Judith, Parel, Serge P.   +2 more
core  

Curcumin ameliorates hyperuricemia and gout‐induced damage via modulating the ROS‐dependent NEK7‐NLRP3 inflammasome activation

Smart Molecules, EarlyView.
Curcumin inhibits the ROS/NEK7‐NLRP3 inflammasome pathway by reducing reactive oxygen species (ROS) levels and disrupting the association of the NEK7‐NLRP3 complex. These combined effects of curcumin result in suppression of the GSDMD‐N pyroptotic pore formation and subsequent reduction of IL‐1β release.
Zhengtian Zhao, Xiaowei Tong, Jing Sun, Jiaqi Lu, Guangyu Zhang, Qing Wang, Li Yang   +6 more
wiley   +1 more source

The reduction of cytochrome c by hypoxanthine and xanthine oxidase [PDF]

, 1952
D.B. Morell
openalex   +1 more source