Results 31 to 40 of about 92,945 (337)
Haematologica, 2017 Hypoxanthine catabolism in vivo is potentially dangerous as it fuels production of urate and, most importantly, hydrogen peroxide. However, it is unclear whether accumulation of intracellular and supernatant hypoxanthine in stored red blood cell units is
T. Nemkov +22 more
semanticscholar +1 more source
Ibrain, EarlyView., 2023 Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen +8 more
wiley +1 more source
Efficient and Practical Radiosynthesis of Novel [131I]-Xanthine and [131I]-Hypoxanthine
Atom Indonesia, 2022 Natural products (NPs) have been the basis for the discovery and development of pharmacologically relevant drug-related molecules, including radiopharmaceuticals.
H. Wongso, W. Nuraeni, E. Rosyidiah
doaj +1 more source
Purine nucleoside phosphorylase: A new marker for free oxygen radical injury to the endothelial cell [PDF]
, 1990 The effect of ischemia and reperfusion on purine nucleoside phosphorylase was studied in an isolated perfused rat liver model. This enzyme is localized primarily in the cytoplasm of the endothelial and Kupffer cells; some activity is associated with the ...
Abouna +32 more
core +1 more source
A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output [PDF]
, 2015 Aerobic exercise, in spite of its multi-organ benefit and potent effect on the metabolome, has yet to be investigated comprehensively via an untargeted metabolomics technology.
Anthony, Nahoum +5 more
core +2 more sources
THE ESTIMATION OF HYPOXANTHINE [PDF]
Journal of Biological Chemistry, 1942 In a previous paper there was described a procedure for the isolation of the purines in a form suitable for the quantitative determination of the individual substances (1). A later publication reported a method for the separation of adenine and hypoxanthine and the determination of the adenine by precipitation of adenine picrate and titration of the ...
openaire +1 more source
Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia
Obesity, 2018 The production of uric acid in murine white adipose tissue (mWAT), and that such production was augmented in obese mice, was recently reported. However, little is known about the secretion of metabolites associated with purine catabolism in human WAT ...
Hirofumi Nagao +14 more
semanticscholar +1 more source
Chemosensors, 2023 Fast protein and metabolite liquid chromatography (FPLMC) was introduced years ago to enable the easy separation of high-molecular compounds such as proteins from small molecules and the identification of the low-molecular substances.
Artur Kuznetsov +15 more
doaj +1 more source
International Journal of Analytical Chemistry, 2018 Uric acid and hypoxanthine are produced in the catabolism of purine. Abnormal urinary levels of these products are associated with many diseases and therefore it is necessary to have a simple and rapid method to detect them.
Nimanthi Wijemanne +3 more
semanticscholar +1 more source
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum [PDF]
, 2009 Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle.
Annette N. Chiang +48 more
core +1 more source