Results 81 to 90 of about 92,945 (337)

Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]

open access: yes, 1994
Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O   +8 more
core   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

open access: yesAnimal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng   +7 more
wiley   +1 more source

First case of hereditary xanthinuria in a Moroccan family

open access: yesPAMJ Clinical Medicine, 2019
The xanthinuria is a rare hereditary autosomal recessive disease. It is related to xanthine oxidase deficiency also known as xanthine dehydrogenase, an enzyme involved in the metabolism of purine bases.
Aicha Ezoubeiri   +4 more
doaj   +1 more source

Late diagnosis of Lesch–Nyhan disease complicated with end-stage renal disease and tophi burst: a case report

open access: yesRenal Failure, 2020
Background Lesch–Nyhan disease (LND) is a rare X-linked recessive inborn error of purine metabolism. Late diagnosis of LND may cause significant morbidity. LND cases have never been reported in Indonesia.
Cahyani Gita Ambarsari   +6 more
doaj   +1 more source

Functional Identification of the Hypoxanthine/Guanine Transporters YjcD and YgfQ and the Adenine Transporters PurP and YicO of Escherichia coli K-12*

open access: yesJournal of Biological Chemistry, 2013
Background: Four putative purine transporter genes represent a distinct homology cluster within family NCS2 in Escherichia coli. Results: The four genes encode high affinity transporters for adenine or hypoxanthine/guanine with essential residues at the ...
Konstantinos Papakostas   +2 more
semanticscholar   +1 more source

Myocardial release of hypoxanthine and lactate during percutaneous transluminal coronary angioplasty [PDF]

open access: yes, 1989
The response of myocardial lactate and hypoxanthine metabolism during percutaneous transluminal coronary angioplasty was studied in a series of 15 patients undergoing this procedure.
Brand, M.J.B.M. (Marcel) van den   +7 more
core   +1 more source

The fate of thiopurine metabolites after switching to low‐dose thiopurine with allopurinol or thioguanine in IBD patients: A retrospective analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Shunting (hypermethylating) thiopurine metabolism, characterized by excessive 6‐MMPR production and (sub)therapeutic 6‐TGN levels, poses a significant challenge in the treatment of inflammatory bowel disease (IBD). This study evaluates the metabolic outcomes of switching to low‐dose thiopurine with allopurinol (LDTA) or thioguanine (TG) in IBD ...
Ahmed B. Bayoumy   +4 more
wiley   +1 more source

Effects of hypoxanthine substitution in peptide nucleic acids targeting KRAS2 oncogenic mRNA molecules: theory and experiment.

open access: yesJournal of Physical Chemistry B, 2013
Genetic disorders can arise from single base substitutions in a single gene. A single base substitution for wild type guanine in the twelfth codon of KRAS2 mRNA occurs frequently to initiate lung, pancreatic, and colon cancer.
J. Sanders   +9 more
semanticscholar   +1 more source

Surface-enhanced Raman spectroscopy for the forensic analysis of vaginal fluid [PDF]

open access: yes, 2016
Vaginal fluid is most often found at crime scenes where a sexual assault has taken place or on clothing or other items collected from sexual assault victims or perpetrators.
Zegarelli, Kathryn Anne
core   +1 more source

New Trends in SERS Substrates With Micro‐ and Nanostructures: Materials, Substrates, Preparation, and Applications

open access: yesBattery Energy, EarlyView.
In this review, the latest research progress in surface‐enhanced Raman scattering (SERS) is discussed comprehensively. It covers four main aspects of SERS technology: materials utilized, various types of SERS substrates, methods employed for their preparation, and recent applications explored in the field over the past few years.
Xiaoyu Tian   +7 more
wiley   +1 more source

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