Results 111 to 120 of about 9,789 (207)

Overproduction of Uric Acid in Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency [PDF]

, 1979
N. Lawrence Edwards, David P. Recker, Irving H. Fox   +2 more
openalex   +1 more source

Efficient cDNA cloning by direct phenotypic correction of a mutant human cell line (HPRT-) using an Epstein-Barr virus derived cDNA expression vector. [PDF]

, 1991
Human cells are, in general, poor recipients of foreign DNA, which has severely hampered the cloning of genes by direct phenotypic correction of deficient human cell lines after DNA mediated gene transfer. In this communication a methodology is presented
Backendorf, C.M.P. (Claude), Belt, P.B.G.M., Hoeijmakers, J.H.J. (Jan), Jongmans, W., Putte, P. (Pieter) van de, Wit, J. (Jan) de   +5 more
core   +2 more sources

Tryptic peptide analysis of normal and mutant forms of hypoxanthine phosphoribosyltransferase from HeLa cells. [PDF]

, 1977
Gregory Milman, S W Krauss, Anne S. Olsen   +2 more
openalex   +1 more source

Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice [PDF]

, 2010
Although most of the proposed beneficial effects of fiber consumption have been attributed to viscous and gel-forming properties of soluble fiber, it is mainly insoluble cereal fiber and whole grains that are strongly associated with reduced diabetes ...
Andreas F.H. Pfeiffer, Backhed, Cameron-Smith, Covington, de Munter, Frank Isken, Galisteo, Hong, Howarth, Isken, Jenkins, Jenkins, King, Kumar, Liese, Martin O. Weickert, Martin Osterhoff, McNeil, Owusu-Asiedu, Pereira, Pittler, Ristow, Robertson, Robertson, Schulze, Song, Steneberg, Stewart, Susanne Klaus, Thorburn, Track, Weickert, Weickert, Weickert, Weickert, Wolfrum, Wolfrum   +36 more
core   +1 more source

Data supporting the design and evaluation of a universal primer pair for pseudogene-free amplification of HPRT1 in real-time PCR

Data in Brief, 2015
Hypoxanthine-guanine phosphoribosyltransferase 1 (HPRT1) is a common housekeeping gene for sample normalization in the quantitative reverse transcriptase polymerase chain (qRT-PCR).
Reza Valadan, Akbar Hedayatizadeh-Omran, Mahdyieh Naghavi Alhosseini-Abyazani, Omolbanin Amjadi, Alireza Rafiei, Mohsen Tehrani, Reza Alizadeh-Navaei   +6 more
doaj   +1 more source

8-AZAGUANINE RESISTANCE IN MAMMALIAN CELLS I. HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE [PDF]

, 1972
Frances D. Gillin, Donald J. Roufa, Arthur L. Beaudet, C. Thomas Caskey   +3 more
openalex   +1 more source

Molecular characterization of a carbon dioxide-dependent Escherichia coli small-colony variant isolated from blood cultures

International Journal of Medical Microbiology, 2020
A carbon dioxide-dependent small-colony variant of Escherichia coli SH4888 was isolated from blood cultures of a patient with cholangitis. To date, little is known regarding the molecular mechanisms leading to formation of carbon dioxide-dependent ...
Takehisa Matsumoto, Masayuki Hashimoto, Ching-Hao Teng, Po-Chuen Hsu, Yusuke Ota, Masaru Takamizawa, Ryosuke Kato, Tatsuya Negishi   +7 more
doaj  

Regulation of scleral cell contraction by transforming growth factor-β and stress competing roles in myopic growth

, 2008
Reduced extracellular matrix accumulation in the sclera of myopic eyes leads to increased ocular extensibility and is related to reduced levels of scleral transforming growth factor-β (TGF-β).
Gentle, Alex, Jobling, Andrew I., McBrien, Neville A., McGowan, Bryan J., Metlapally, Ravikanth   +4 more
core  

Whole Exome Sequencing Facilitates Early Diagnosis of Lesch–Nyhan Syndrome: A Case Series

Diagnostics
Background: Lesch–Nyhan syndrome (LNS) is a rare X-linked recessive metabolic disorder caused by mutations in the HPRT1 gene, resulting in hypoxanthine–guanine phosphoribosyltransferase (HPRT) deficiency.
Hung-Hsiang Fang, Chung-Lin Lee, Hui-Ju Chen, Chih-Kuang Chuang, Huei-Ching Chiu, Ya-Hui Chang, Yuan-Rong Tu, Yun-Ting Lo, Hsiang-Yu Lin, Shuan-Pei Lin   +9 more
doaj   +1 more source

Оцінювання мутагенної активності епоксидвмісних поліоксипропілентріолів у короткотривалих експериментах із використанням тканинних культур і бактерій [PDF]

, 2015
Introduction. Many chemicals polluting the environment can exert a specific impact on the body with significant general toxic effects, manifested not in the period of exposure and not immediately after it, but in remote periods in the life of individuals,
Кучерявенко, М.А.
core