Results 81 to 90 of about 13,871 (203)

Targeted Nucleotide Substitution in Mammalian Cell by Target-AID

Bio-Protocol, 2017
Programmable RNA-guided nucleases based on CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated protein) systems have been applied to various type of cells as powerful genome editing tools. By using activation-induced
Takayuki Arazoe, Keiji Nishida, Akihiko Kondo   +2 more
doaj   +1 more source

8-AZAGUANINE RESISTANCE IN MAMMALIAN CELLS I. HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE [PDF]

, 1972
Frances D. Gillin, Donald J. Roufa, Arthur L. Beaudet, C. Thomas Caskey   +3 more
openalex   +1 more source

Expression of Interleukin-8 Promotes Neutrophil Infiltration and Genetic Instability in Mutatect Tumors

Neoplasia: An International Journal for Oncology Research, 2000
Neutrophils represent a potential source of genotoxic reactive oxygen and nitrogen species in the tumor microenvironment. Using Mutatect cell lines, which can form subcutaneous tumors in syngeneic C57BL/6 mice, we have previously established that the ...
Arsalan S. Haqqani, Jagdeep K. Sandhu, H. Chaim Birnboim   +2 more
doaj   +1 more source

Perfecting a high hypoxanthine phosphoribosyltransferase activity-uricase KO mice to test the effects of purine- and non-purine-type xanthine dehydrogenase (XDH) inhibitors. [PDF]

Br J Pharmacol, 2020
Hosoya T, Uchida S, Shibata S, Tomioka NH, Hosoyamada M.   +4 more
europepmc   +1 more source

Molecular characterization of a carbon dioxide-dependent Escherichia coli small-colony variant isolated from blood cultures

International Journal of Medical Microbiology, 2020
A carbon dioxide-dependent small-colony variant of Escherichia coli SH4888 was isolated from blood cultures of a patient with cholangitis. To date, little is known regarding the molecular mechanisms leading to formation of carbon dioxide-dependent ...
Takehisa Matsumoto, Masayuki Hashimoto, Ching-Hao Teng, Po-Chuen Hsu, Yusuke Ota, Masaru Takamizawa, Ryosuke Kato, Tatsuya Negishi   +7 more
doaj  

Overproduction of Uric Acid in Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency [PDF]

, 1979
N. Lawrence Edwards, David P. Recker, Irving H. Fox   +2 more
openalex   +1 more source

Tryptic peptide analysis of normal and mutant forms of hypoxanthine phosphoribosyltransferase from HeLa cells. [PDF]

, 1977
Gregory Milman, S W Krauss, Anne S. Olsen   +2 more
openalex   +1 more source

Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells. [PDF]

, 1989
Beverly H. Koller, Lora J. Hagemann, Thomas Doetschman, John R. Hagaman, Shaobai Huang, Parker Williams, N. L. First, Nobuo Maeda, O. Smithies   +8 more
openalex   +1 more source

Human hypoxanthine-guanine phosphoribosyltransferase. Demonstration of structural variants in lymphoblastoid cells derived from patients with a deficiency of the enzyme. [PDF]

, 1982
James M. Wilson, Bennett W. Baugher, P M Mattes, Peter E. Daddona, William N. Kelley   +4 more
openalex   +1 more source

Characterisation of cDNA clones for hypoxanthine–guanine phosphoribosyltransferase from the human malarial parasite,Plasmodium falciparum: comparisons to the mammalian gene and protein [PDF]

, 1987
Angus King, David W. Melton
openalex   +1 more source