Results 211 to 220 of about 348,583 (245)

Proteomic analysis identifying proteins relevant for treatment success following experimental neonatal inflammation-sensitized hypoxia-ischemia. [PDF]

Pediatr Res
Burkard H, Osredkar D, Maes E, Bernis ME, Bremer AS, Zweyer M, Dowling P, Ohlendieck K, Thoresen M, Sabir H.   +9 more
europepmc   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

Novel purine derivatives mitigate hypoxia ischemia related brain injury through agrin, zyxin and synaptotagmin proteins. [PDF]

Neurotherapeutics
Mabondzo A, Disdier C, Bouzid A, Larbi KS, Tsintzou A, Maïza A, Kim B, Costa N, Harati R, Nguyen AL, Pruvost A, Galons H, Oumata N, Armengaud J, Knijnenburg M, Verma G, Hagberg H, Gressens P, Chen XF, Hamoudi RA, Stonestreet BS.   +20 more
europepmc   +1 more source

Endoscopic Suture Ligation and Sclerotherapy for Pharyngolaryngeal Venous Malformation

The Laryngoscope, EarlyView.
This study evaluated suture ligation combined with sclerotherapy in 53 patients with pharyngolaryngeal venous malformations. A single procedure achieved complete resolution in 79.25% of cases, with no serious complications or need for prophylactic tracheostomy.
Jiajun Tian, Juke Ma, Ahmad A. Hariri, Zhenghua Lv, Peng Cui, Wei Xu   +5 more
wiley   +1 more source

The Neuroprotective Effects of Caffeine in a Neonatal Hypoxia-Ischemia Model are Regulated through the AMPK/mTOR Pathway. [PDF]

Int J Biol Sci
Bernis ME, Burkard H, Bremer AS, Grzelak K, Zweyer M, Maes E, Nacarkucuk E, Kaibel H, Hakvoort C, Müller A, Sabir H.   +10 more
europepmc   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Neuroprotective Effect of Melatonin in a Neonatal Hypoxia-Ischemia Rat Model Is Regulated by the AMPK/mTOR Pathway. [PDF]

J Am Heart Assoc
Nacarkucuk E, Bernis ME, Bremer AS, Grzelak K, Zweyer M, Maes E, Burkard H, Sabir H.   +7 more
europepmc   +1 more source

Perinatal Caffeine Administration Improves Outcomes in an Ovine Model of Neonatal Hypoxia-Ischemia. [PDF]

Stroke
Mike JK, White Y, Ha J, Iranmahboub A, Hawkins C, Hutchings RS, Vento C, Manzoor H, Wang A, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JVS, Long-Boyle J, Fineman JR, Ferriero DM, Maltepe E.   +16 more
europepmc   +1 more source

GMMAS: Glioma Multiparametric MRI Analysis System for Fully‐Automated Layered Tumor Diagnosis and Prognostic Evaluation

Medicine Advances, EarlyView.
We developed the Glioma Multiparametric MRI Analysis System (GMMAS), a fully automated platform that leverages multi‐task semi‐supervised learning to diagnose gliomas from multiparametric MRI images. It provides accurate tumor segmentation, subtyping, and prognostic predictions, offering a user‐friendly tool for clinicians to enhance diagnosis and ...
Yihao Liu, Zhihao Cui, Liming Li, Junjie You, Xinle Feng, Ruixuan Huang, Jianxin Wang, Xiangyu Wang, Qing Liu, Minghua Wu   +9 more
wiley   +1 more source

Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method. [PDF]

Front Genet
Zhang Y, Liu J, Basang Z, Yang Q, Chen H, Chen S, Li S, Lei C, Fang M, Liu H, Jin X, Wang Y.   +11 more
europepmc   +1 more source