Results 221 to 230 of about 348,583 (245)

Lactate Dehydrogenase A and a Novel Four‐Gene Signature as Dual Diagnostic Markers for Lung Adenocarcinoma and Ischemic Stroke

Medicine Advances, EarlyView.
This study identified shared molecular alterations between lung adenocarcinoma (LUAD) and ischemic stroke (IS) through integrative transcriptomic analysis of TCGA‐LUAD and GSE146882 datasets, revealing a four‐gene diagnostic signature (LDHA, NME4, SLC25A39, and SLC7A5) with high accuracy across both diseases. Among these, LDHA was further identified as
Jin Xie, Gao‐Chun Xiao, Xin‐Yang Qu, Rui‐Min Wu, Yu‐Long Zou, Xue Hu, Xu‐Sheng Liu   +6 more
wiley   +1 more source

The Impact of the Histone Deacetylase Inhibitor-Sodium Butyrate on Complement-Mediated Synapse Loss in a Rat Model of Neonatal Hypoxia-Ischemia. [PDF]

Mol Neurobiol
Ziabska K, Gewartowska M, Frontczak-Baniewicz M, Sypecka J, Ziemka-Nalecz M.   +4 more
europepmc   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

Hypothermia treatment in Hypoxia-Inducible Factor-1α Knockout Mice with Hypoxia-Ischemia.

Dev Neurosci
Sheldon RA, Jiang X, Lu F, Stewart NR, Ferriero DM.   +4 more
europepmc   +1 more source

Targeting the Multiple Complex Processes of Hypoxia-Ischemia to Achieve Neuroprotection. [PDF]

Int J Mol Sci
Maïza A, Hamoudi R, Mabondzo A.
europepmc   +1 more source

Fetal Brain Abnormalities Following Laser Surgery for Twin‐to‐Twin Transfusion Syndrome: Imaging Patterns and Evolution

Prenatal Diagnosis, EarlyView.
ABSTRACT Introduction Severe brain injury has been reported following fetoscopic laser ablation (FLA) for twin‐to‐twin transfusion syndrome (TTTS), but imaging patterns and temporal evolution remain poorly defined. This study aimed to characterize the progression of severe brain injury after FLA. Methods We conducted a retrospective case series of TTTS
Yada Kunpalin, Elka Miller, Ingrid Larsen, Kamini Raghuram, Catherine Windrim, Nimrah Abbasi, Greg Ryan, Tim Van Mieghem, Shiri Shinar   +8 more
wiley   +1 more source

Pretreatment with oleuropein protects the neonatal brain from hypoxia-ischemia by inhibiting apoptosis and neuroinflammation. [PDF]

J Cereb Blood Flow Metab
Reyes-Corral M, Gil-González L, González-Díaz Á, Tovar-Luzón J, Ayuso MI, Lao-Pérez M, Montaner J, de la Puerta R, Fernández-Torres R, Ybot-González P.   +9 more
europepmc   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Genistein-3'-sodium sulfonate enhances neurological function in neonatal rats with hypoxia-ischemia during the recovery period. [PDF]

Heliyon
Shuang L, Liu G, Huang Y, Xie T, Lin H, Liu R, Xue J, Huang Z, Jiang L.   +8 more
europepmc   +1 more source

Nomogram integrating MRI radiomics and white matter hyperintensity grading for predicting overall survival in patients with non‐small cell lung cancer and brain metastases receiving whole‐brain radiotherapy

Precision Radiation Oncology, EarlyView.
A prognostic nomogram integrating radiomic features and white matter hyperintensity (WMH) grading was developed to enable individualized survival prediction in patients with brain metastases (BMs). Integration of these imaging biomarkers into the clinical model enhanced predictive performance, indicating their incremental prognostic value for BM ...
Jianan Ni, Yuefeng Lu, Haoli Xu, Xuni Xu, Mengjing Zhao, Yingnan Xue, Gang Li, Yuxia Duan   +7 more
wiley   +1 more source