Results 81 to 90 of about 432,269 (136)

GFAP mRNA expression in mice after hypoxia-ischemia, assessed by quantitative rt-PCR.

open access: yes, 2013
Cortex from wild-type mice exposed to hypoxia-ischemia on P9, examined by quantitative rt-PCR immediately after (n = 6), 6 h (n = 4), 24 h (n = 3), 3d (n = 4), 7d (n = 4), and 21d (n = 4) after hypoxia-ischemia.
Maryam Faiz (365377)   +9 more
core   +1 more source

When the gatekeeper falls: developmental vulnerability of the thalamic reticular nucleus in neonatal and pediatric hypoxic-ischemic brain injury

open access: yesFrontiers in Systems Neuroscience
The thalamic reticular nucleus orchestrates thalamocortical oscillations and sensory gating. Its early development features a unique confluence of depolarizing GABA signaling, immature chloride regulation, and transient electrical coupling via connexin ...
Kuangfu Hsiao, Kuangfu Hsiao
doaj   +1 more source

Effects of hypoxia and ischemia on autoregulation in postnatal intestine

open access: yes, 1991
Pressure-flow autoregulation was quantified within in vitro intestine from 3- and 35-day-old swine before and after lowering arterial PO2 (hypoxia) or lowering baseline blood flow by means of norepinephrine infusion (ischemia).
P. T. Nowicki   +2 more
core   +1 more source

Hemin as a protective agent in an in vitro model of hypoxia/reoxygenation-induced injury

open access: yesSAGE Open Medicine
Objective: Ischemia-reperfusion injury exacerbates myocardial damage and affects the prognosis of patients with ST-elevation myocardial infarction. This study investigates the potential cytoprotective effects of hemin in an in vitro cardiomyocyte model ...
Zuoyan Wang, Wei Liu
doaj   +1 more source

LncRNA GABPB1-IT1 is upregulated in ischemia-induced acute kidney injury and downregulates miR-204-5p to promote hypoxia-induced human renal proximal tubular epithelial cell apoptosis

open access: yesKidney & Blood Pressure Research
Introduction: The present study investigated the role of long non-coding RNA (lncRNA) GABPB1-IT1 in ischemia-induced acute kidney injury (AKI). Methods: The expression of GABPB1-IT1 in plasma of patients with ischemia-induced AKI and healthy controls ...
Fang Feng, Ru Zhang, Lihong Long
doaj   +1 more source

Preparation of Nanoparticles Loaded with Membrane-Impermeable Peptide AC3-I and Its Protective Effect on Myocardial Ischemia and Reperfusion

open access: yesPharmaceutics
Purpose: It is well known that inhibition of Ca2+/calmodulin-dependent protein kinase II (CaMKII) provides cardiac protection in cases of myocardial ischemia–reperfusion injury.
Yi Liu   +5 more
doaj   +1 more source

Hypoxic and ischemic effects on gene and protein expression levels of paracrine factors by human olfactory mucosa mesenchymal-like stem cells

open access: yesJournal of Neurorestoratology, 2016
Ting Yuan,1* Yi Zhuo,1* Chaying Su,2 Xuan Li,1 Da Duan,1 Lite Ge,1 Pei Wu,1 Hao Wang,1 Yujia Deng,1 Ming Lu1 1Department of Neurosurgery, Second Affiliated Hospital of Hunan Normal University (163 Hospital of the People’s Liberation Army), Changsha,
Yuan T   +9 more
doaj  

A comparison of hepatic ischemia/hypoxia-reperfusion injury models

open access: yes
A number of hepatic ischemia/hypoxia–reperfusion models have been described. This study characterised the functional and structural changes induced by the most commonly used in vivo and in situ models for hypoxia/ischemia-reperfusion in the rat liver.
Arab, Hossein-Ali   +5 more
core  

Hypoxia–ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter

open access: yes, 2006
Ischemia is implicated in periventricular white matter injury (PWMI), a lesion associated with cerebral palsy. PWMI features selective damage to early cells of the oligodendrocyte lineage, a phenomenon associated with glutamate receptor activation.
Robert J. Kayton (7595006)   +6 more
core   +1 more source

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