Results 61 to 70 of about 432,269 (136)

Inflammatory gene profiling in the developing mouse brain after hypoxia-ischemia

, 2004
Brain ischemia triggers an inflammatory reaction that progresses for days to weeks and seems to have a role in secondary progression of injury. Inflammation induces a complex pattern of signaling molecules with partly contradictory actions, and the ...
Hagberg, Henrik,, Mallard, Carina,, Hedtjärn, Maj,   +2 more
core   +2 more sources

A comparison between chemical and gas hypoxia as models of global ischemia in zebrafish (Danio rerio)

Animal Models and Experimental Medicine, 2020
Background Zebrafish models for neurovascular diseases offer new methods for elucidation of molecular pathways to tissue damage. External fertilization and high fecundity provide opportunities for transgenics and other forms of genetic manipulation that ...
Kaitlyn M. Marino, Emani R. Silva, James A. Windelborn   +2 more
doaj   +1 more source

Behavioral performance of rats following neonatal hypoxia-ischemia.

, 1986
The behavioral performance of rats subjected in the neonatal period to hypoxia-ischemia at either 37 degrees C or 21 degrees C was compared to that of sham-ligated animals.
J Kolonich, S K Yagel, C L Woods, R S Young   +3 more
core   +1 more source

O-GlcNAcylation of YAP1 promotes lung transplant ischemia-reperfusion injury via binding to HIF1α transcription factor and activating autophagy and mitophagy

Cell Death and Disease
Lung transplant ischemia-reperfusion injury poses a significant challenge in transplantation medicine, often causing severe complications and poor patient outcomes.
Shaohua Dai, Xuemei Wan, Lingchun Xia, Lei Xu, Chunfan Xie, Guohui Wang, Jian Tang   +6 more
doaj   +1 more source

Detrimental Role of Corticotropin-Releasing Factor on the Decrease of CA1 Field Potential Induced by In Vitro Ischemia in Rat Hippocampal Slices

Journal of Pharmacological Sciences, 2004
This experiment was designed to test the hypothesis that endogenous corticotropin-releasing factor (CRF) contributes to the neurodegenerative process following an ischemic insult.
Yoshifumi Kagamiishi, Tsuneyuki Yamamoto, Shigenori Watanabe   +2 more
doaj   +1 more source

Effects of intermittent versus chronic hypoxia on myocardial ischemic tolerance

, 2011
Hypoxia, or low supply of oxygen with respect to need, represents a critical risk factor that augments severity and impairs outcome of myocardial ischemia. However, systemic hypoxia is sometimes a cardioprotective rather than risk factor. Three different
Samaja M., Veicsteinas A., Milano G.
core   +1 more source

Role of cation gradients in hypercontracture of myocytes during simulated ischemia and reperfusion [PDF]

, 1993
We examined the relationship between transsarcolemmal cation gradients and hypercontracture of cardiac myocytes in ischemia and reperfusion using adult rat ventricular myocytes superfused with buffer mimicking normal or ischemic extracellular fluid ...
J. P. Navas, Marsh, J. D., R. A. Kelly, J. D. Marsh, Krämer, Bernhard K., Kelly, R. A., Nishida, M., T. W. Smith, Smith, T. W., M. Nishida, B. Kraemer, Borzak, S., S. Borzak, Navas, J. P.   +13 more
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Hypoxia-ischemia and retinal ganglion cell damage

, 2008
Charanjit Kaur1, Wallace S Foulds2, Eng-Ang Ling11Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; 2Singapore Eye Research Institute, SingaporeAbstract: Retinal hypoxia is the potentially blinding ...
Eng-Ang Ling, Wallace S Foulds, Charanjit Kaur   +2 more
core  

Neuroprotection by selective nitric oxide synthase inhibition at 24 hours after perinatal hypoxia-ischemia

, 2002
Background and Purpose— Perinatal hypoxia-ischemia is a major cause of neonatal morbidity and mortality. Until now no established neuroprotective intervention after perinatal hypoxia-ischemia has been available.
Tweel, van den, E., Nicolaij, K., Zhu, C., Kops, N., Blomgren, K., Peeters-Scholte, C., Bär, D., Bel, van, F., Groenendaal, F., Buul-Offers, van, S., Koster, J., Veldhuis, W.B., Hagberg, H.   +12 more
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Effects of Acute Systemic Hypoxia and Hypercapnia on Brain Damage in a Rat Model of Hypoxia-Ischemia. [PDF]

, 2016
Therapeutic hypercapnia has the potential for neuroprotection after global cerebral ischemia. Here we further investigated the effects of different degrees of acute systemic hypoxia in combination with hypercapnia on brain damage in a rat model of ...
Xianhai Fang (3373421), Xianhai Fang, Nan Wang (21935), Xuezhong Zhang, Tao Tao (19313), Xuezhong Zhang (3373427), Jing Tan, Qi Wang (22418), Nan Wang, Wanchao Yang, Wanchao Yang (3373424), Tao Tao, Qi Wang, Jing Tan (2230783), Wenzhi Li (617452), Wenzhi Li, Zhang Xuezhong, Wang Nan, Tan Jing, Li Wenzhi, Wang Qi, Fang Xianhai, Yang Wanchao   +22 more
core   +1 more source