Results 51 to 60 of about 432,269 (136)
PLoS ONE, 2012 Perinatal hypoxia-ischemia is a major cause of acute mortality in newborns and cognitive and motor impairments in children. Cerebral hypoxia-ischemia leads to excitotoxicity and necrotic and apoptotic cell death, in which mitochondria play a major role ...
Cláudia S F Queiroga +5 more
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The Role of Endothelin in Mediating Ischemia/Hypoxia-Induced Atrial Natriuretic Peptide Release
, 2015 The aim of the present study was to investigate the putative role of endothelin (ET) in mediating ischemia/hypoxia-induced ANP release utilizing exogenous ET-1 or ET receptor antagonists (BQ-123 or Bosentan).
Oliver, J M, Zhang, Yi, Horowitz, John D
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Data in Brief, 2018 The data contain body weights, plasma free fatty acids concentrations and cardiac uncoupling protein-3 protein levels for wild-type and mdx mice. The data provide heart rates, left ventricular contractile functions, coronary flow, phosphocreatine ...
Wen Zhang +4 more
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Hypoxia-induced signaling in angiogenesis : role of mTOR, HIF and Angiotensin II [PDF]
, 2007 This thesis includes the work of four different projects I have been following during my time as a PhD student; (1) the characterization of mTOR-associated signaling and endothelial cell proliferation in response to hypoxia, and (2) identification of ...
Petrimpol, Marco Renato
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Effects of intermittent versus chronic hypoxia on myocardial ischemic tolerance
, 2013 Hypoxia, or low supply of oxygen with respect to need, represents a critical risk factor that augments severity and impairs outcome of myocardial ischemia. However, systemic hypoxia is sometimes a cardioprotective rather than risk factor. Three different
Samaja M., Veicsteinas A., Milano G.
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Molecular Genetics & Genomic MedicineBackground This study aimed to screen and identify core hypoxia‐ischemia‐related genes associated with myocardial infarction (MI). Method Two transcriptomic datasets, GSE97320 and GSE48060, were retrieved from the Gene Expression Omnibus (GEO) database ...
Longsheng Zhang, Ning Liang
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Mouse renal 4T1 cell engraftment as a model to study the influence of hypoxia in breast cancer progression [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To develop a mouse model to study the influence of hypoxia in breast cancer progression and metastasis. METHODS: The 4T1 cell line was used to engraft the kidneys of female BALB/c mice.
Heriton Marcelo Ribeiro Antonio +5 more
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Pre- and Perinatal Ischemia-Hypoxia, the Ischemia-Hypoxia Response Pathway, and ADHD Risk [PDF]
, 2016 This review focuses on how measured pre- and perinatal environmental and (epi)genetic risk factors are interrelated and potentially influence one, of many, common developmental pathway towards ADHD. Consistent with the Developmental Origins of Health and
Schmidt-Kastner, Rainald +4 more
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Lipopolysaccharide and hypoxia/ischemia induced IL-2 expression by microglia in neonatal brain
, 2008 Using a model of perinatal brain lesions induced by lipopolysaccharide and hypoxia/ischemia, we hypothesized that interleukin-2 (IL-2), a neurotoxic cytokine, was enhanced within injured brains.
Kadhim, Hazim +5 more
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Global gene expression in the immature brain after hypoxia-ischemia
, 2004 Ischemia induces a complex response of differentially expressed genes in the brain. In order to understand the specific mechanisms of injury in the developing brain, it is important to obtain information on global changes in the transcriptome after ...
Hagberg, Henrik, +4 more
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