Results 31 to 40 of about 123,337 (240)

Effect of hypoxic preconditioning on brain genomic response before and following ischemia in the adult mouse: Identification of potential neuroprotective candidates for stroke

open access: yesNeurobiology of Disease, 2006
The aim of the present study is to better understand oxygen-sensitive adaptative pathways underlying the hypoxic preconditioning-induced protection of the brain against ischemia.
Yang Tang   +6 more
doaj   +1 more source

Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care [PDF]

open access: yes, 2012
Author can archive publisher's pdf. Free via Creative Commons: CC-BENCHTOBEDSIDE-2.0.
Nandra, KK, Patel, NSA, Thiemermann, C
core   +1 more source

Tetrahydrobiopterin in antenatal brain hypoxia-ischemia-induced motor impairments and cerebral palsy

open access: yesRedox Biology, 2017
Antenatal brain hypoxia-ischemia, which occurs in cerebral palsy, is considered a significant cause of motor impairments in children. The mechanisms by which antenatal hypoxia-ischemia causes brain injury and motor deficits still need to be elucidated ...
Jeannette Vasquez-Vivar   +4 more
doaj   +1 more source

PCSK9 Promotes Hypoxia-Induced EC Pyroptosis by Regulating Smac Mitochondrion-Cytoplasm Translocation in Critical Limb Ischemia

open access: yesJACC: Basic to Translational Science, 2023
Summary: Hypoxia-induced endothelial cell death and impaired angiogenesis are the main pathophysiological features of critical limb ischemia. Mechanistically, proprotein convertase subtilisin/kexin type 9 (PCSK9) promoted Smac translocation from ...
Meixin Zhang, MM   +9 more
doaj   +1 more source

Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy. [PDF]

open access: yes, 2017
Global patterns of brain injury correlate with motor, cognitive, and language outcomes in survivors of neonatal encephalopathy (NE). However, it is still unclear whether local changes in brain structure predict specific deficits.
Barkovich, A James   +9 more
core   +2 more sources

Plasticity in the Neonatal Brain following Hypoxic-Ischaemic Injury [PDF]

open access: yes, 2016
Hypoxic-ischaemic damage to the developing brain is a leading cause of child death, with high mortality and morbidity, including cerebral palsy, epilepsy, and cognitive disabilities.
Hristova, M, Rocha-Ferreira, E
core   +7 more sources

Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter [PDF]

open access: yes, 2015
Remote ischemic postconditioning (RIPostC) is a promising therapeutic intervention whereby brief episodes of ischemia/reperfusion of one organ (limb) mitigate damage in another organ (brain) that has experienced severe hypoxia-ischemia.
Alonso-Alconada, Daniel   +19 more
core   +2 more sources

Tannic Acid Improves Renal Function Recovery after Renal Warm Ischemia–Reperfusion in a Rat Model

open access: yesBiomolecules, 2020
Background and purpose: Ischemia−reperfusion injury is encountered in numerous processes such as cardiovascular diseases or kidney transplantation; however, the latter involves cold ischemia, different from the warm ischemia found in vascular ...
Louise Alechinsky   +10 more
doaj   +1 more source

Neuronal vulnerability to fetal hypoxia-reoxygenation injury and motor deficit development relies on regional brain tetrahydrobiopterin levels

open access: yesRedox Biology, 2020
Hypertonia is pathognomonic of cerebral palsy (CP), often caused by brain injury before birth. To understand the early driving events of hypertonia, we utilized magnetic resonance imaging (MRI) assessment of early critical brain injury in rabbit fetuses (
Jeannette Vasquez-Vivar   +6 more
doaj   +1 more source

Role of Antioxidants in Neonatal Hypoxic–Ischemic Brain Injury: New Therapeutic Approaches [PDF]

open access: yes, 2017
Hypoxic-ischemic brain damage is an alarming health and economic problem in spite of the advances in neonatal care. It can cause mortality or detrimental neurological disorders such as cerebral palsy, motor impairment and cognitive deficits in neonates ...
Arteaga Cabeza, Olatz   +5 more
core   +3 more sources

Home - About - Disclaimer - Privacy